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A deterministic multi-stage malaria model with a non-therapeutic control measure, the use of mosquito bednet is formulated and analyzed. The model basic reproduction number is derived, and analytical results show that the models equilibria…

Populations and Evolution · Quantitative Biology 2020-07-21 S. Y. Tchoumi , Y. T. Kouakep , D. J. Fotsa Mbogne , J. C. Kamgang , J. M. Tchuenche

In this study, we develop a multi criteria model to identify dengue outbreak periods. To validate the model, we performed a simulation using dengue transmission-related data in Sri Lanka's Western Province. Our results indicated that the…

Optimization and Control · Mathematics 2022-09-08 Piotr Jakubowski , Hasitha Erandi , Anuradha Mahasinghe , Sanjeewa Perera , Andrzej Ameljańczyk

Enlightened from the inverse consideration of the stable continuous-time dynamics evolution, the Variation Evolving Method (VEM) analogizes the optimal solution to the equilibrium point of an infinite-dimensional dynamic system and solves…

Systems and Control · Computer Science 2018-01-08 Sheng Zhang , Bo Liao , Fei Liao

We study a multi-agent system for the modeling maritime crime. The model involves three interacting populations of ships: commercial ships, pirate ships, and coast guard ships. Commercial ships follow commercial routes, are subject to…

Optimization and Control · Mathematics 2023-04-11 Gianluca Orlando

Dengue remains one of Brazil's major epidemiological challenges, marked by strong intra-urban inequalities and the influence of climatic and socio-environmental factors. This study analyzed confirmed dengue cases in Recife from 2015 to 2024…

We investigate a mathematical model in crop pest management, considering plant biomass, pest, and the effect of farming awareness. The pest population is divided into two compartments: susceptible pest and infected pest. We assume that the…

Optimization and Control · Mathematics 2021-03-30 Teklebirhan Abraha , Fahad Al Basir , Legesse Lemecha Obsu , Delfim F. M. Torres

We investigate a mathematical model in crop pest controlling, considering plant biomass, pest, and the effect of farming awareness. The pest population is divided into two compartments: susceptible pests and infected pests. We assume that…

Optimization and Control · Mathematics 2022-01-28 Teklebirhan Abraha , Fahad Al Basir , Legesse Lemecha Obsu , Delfim F. M. Torres

In this paper we make the first steps to bridge the gap between classic control theory and modern, network-based epidemic models. In particular, we apply nonlinear model predictive control (NMPC) to a pairwise ODE model which we use to…

Classical Analysis and ODEs · Mathematics 2014-02-11 Fanni Sélley , Ádám Besenyei , Istvan Z. Kiss , Péter L. Simon

A Caputo fractional-order mathematical model for the transmission dynamics of tuberculosis (TB) was recently proposed in [Math. Model. Nat. Phenom. 13 (2018), no. 1, Art. 9]. Here, a sensitivity analysis of that model is done, showing the…

Optimization and Control · Mathematics 2019-08-12 Silverio Rosa , Delfim F. M. Torres

Malaria is a life threatening disease, entirely preventable and treatable, provided the currently recommended interventions are properly implemented. These interventions include vector control through the use of insecticide-treated nets…

Optimization and Control · Mathematics 2013-08-01 Cristiana J. Silva , Delfim F. M. Torres

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

Optimization and Control · Mathematics 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

The paper presents an approach to studying optimal control problems in the space of nonnegative measures with dynamics given by a nonlocal balance law. This approach relies on transforming the balance law into a continuity equation in the…

Optimization and Control · Mathematics 2025-01-30 Nikolay Pogodaev , Maxim Staritsyn

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

Cell heterogeneity plays an important role in patient responses to drug treatments. In many cancers, it is associated with poor treatment outcomes. Many modern drug combination therapies aim to exploit cell heterogeneity, but determining…

Quantitative Methods · Quantitative Biology 2025-02-18 Simon F. Martina-Perez , Samuel W. S. Johnson , Rebecca M. Crossley , Jennifer C. Kasemeier , Paul M. Kulesa , Ruth E. Baker

Dengue incidence forecasting using hybrid models has been surging in the data rich world. Hybridization of statistical time series forecasting models and machine learning models are explored for dengue forecasting with different degrees of…

Populations and Evolution · Quantitative Biology 2023-12-27 I. Ghosh , S. Gupta , S. Rana

An impulsive model of augmentative biological control consisting of a general continuous predator-prey model in ordinary differential equations augmented by a discrete part describing periodic introductions of predators is considered. It is…

Optimization and Control · Mathematics 2009-09-29 Ludovic Mailleret , Frédéric Grognard

Optimal Control (OC) is the process of determining control and state trajectories for a dynamic system, over a period of time, in order to optimize a given performance index. With the increasing of variables and complexity, OC problems can…

Optimization and Control · Mathematics 2014-09-02 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

This paper introduces a novel concept for addressing non-convexity in the cost functions of distributed economic model predictive control (DEMPC) systems. Specifically, the proposed algorithm enables agents to self-organize into a hierarchy…

Systems and Control · Electrical Eng. & Systems 2020-10-21 Ali C. Kheirabadi , Ryozo Nagamune

We derive a framework to compute optimal controls for problems with states in the space of probability measures. Since many optimal control problems constrained by a system of ordinary differential equations (ODE) modelling interacting…

Optimization and Control · Mathematics 2020-09-23 Martin Burger , René Pinnau , Claudia Totzeck , Oliver Tse

In this study, we used a dataset of approximately 96,000 reported dengue cases from 2015 to 2024 in Recife, the capital of northeastern Brazil, all geocoded by neighborhood. The dataset was enriched with sociodemographic data from the…

Other Quantitative Biology · Quantitative Biology 2025-07-17 Marcílio Ferreira dos Santos , Andreza dos Santos Rodrigues de Melo