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Cardiovascular disease is the primary cause of death globally, necessitating early identification, precise risk classification, and dependable decision-support technologies. The advent of large language models (LLMs) provides new zero-shot…

Background: The concept of combinatorial biomarkers was conceived around 2010: it was noticed that simple biomarkers are often inadequate for recognizing and characterizing complex diseases. Methods: Here we present an algorithmic search…

Neurons and Cognition · Quantitative Biology 2013-12-09 Balazs Szalkai , Vince K. Grolmusz , Vince I. Grolmusz , Coalition Against Major Diseases

Background: Selecting feature genes to predict phenotypes is one of the typical tasks in analyzing genomics data. Though many general-purpose algorithms were developed for prediction, dealing with highly correlated genes in the prediction…

Applications · Statistics 2022-04-11 Li Xing , Songwan Joun , Kurt Mackay , Mary Lesperance , Xuekui Zhang

Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Sricharan Vijayarangan , Balamurali Murugesan , Vignesh R , Preejith SP , Jayaraj Joseph , Mohansankar Sivaprakasam

ICU mortality scoring systems attempt to predict patient mortality using predictive models with various clinical predictors. Examples of such systems are APACHE, SAPS and MPM. However, most such scoring systems do not actively look for and…

Neural and Evolutionary Computing · Computer Science 2016-04-25 Chee Chun Gan , Gerard Learmonth

We review some of the latest approaches to analysing cardiac electrophysiology data using machine learning and predictive modelling. Cardiac arrhythmias, particularly atrial fibrillation, are a major global healthcare challenge. Treatment…

Cardiovascular disease (CVD) remains a critical global health concern, demanding reliable and interpretable predictive models for early risk assessment. This study presents a large-scale analysis using the Heart Disease Health Indicators…

Machine Learning · Computer Science 2025-11-05 Md Abrar Hasnat , Md Jobayer , Md. Mehedi Hasan Shawon , Md. Golam Rabiul Alam

Ischemic heart disease (IHD), particularly in its chronic stable form, is a subtle pathology due to its silent behavior before developing in unstable angina, myocardial infarction or sudden cardiac death. Machine learning techniques applied…

Signal Processing · Electrical Eng. & Systems 2020-11-20 Giulia Silveri , Marco Merlo , Luca Restivo , Gianfranco Sinagra , Agostino Accardo

From a fresh data science perspective, this thesis discusses the prediction of coronary artery disease based on genetic variations at the DNA base pair level, called Single-Nucleotide Polymorphisms (SNPs), collected from the Ontario Heart…

Machine Learning · Computer Science 2014-02-04 Hubert Haoyang Duan

Metabolomic data can potentially enable accurate, non-invasive and low-cost prediction of coronary artery disease. Regression-based analytical approaches however might fail to fully account for interactions between metabolites, rely on a…

Many people are currently suffering from heart diseases that can lead to untimely death. The most common heart abnormality is arrhythmia, which is simply irregular beating of the heart. A prediction system for the early intervention and…

Signal Processing · Electrical Eng. & Systems 2018-06-22 Aboul Ella Hassanien , Moataz Kilany , Essam H. Houssein

Heart diseases are the main international cause of human defunction. According to the WHO, nearly 18 million people decease each year because of heart diseases. Also considering the increase of medical data, much pressure is put on the…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Andrés Bell-Navas , Nourelhouda Groun , María Villalba-Orero , Enrique Lara-Pezzi , Jesús Garicano-Mena , Soledad Le Clainche

Disease gene prioritization assigns scores to genes or proteins according to their likely relevance for a given disease based on a provided set of seed genes. Here, we describe a new algorithm for disease gene prioritization based on…

Quantum Physics · Physics 2023-11-10 Harto Saarinen , Mark Goldsmith , Rui-Sheng Wang , Joseph Loscalzo , Sabrina Maniscalco

We intend to create a new risk assessment methodology that combines the best characteristics of both risk score and machine learning models. More specifically, we aim to develop a method that, besides having a good performance, offers a…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

Despite extensive research during the last decades, coronary artery disease (CAD) remains the number one cause of death, responsible for near 50% of global mortality. A main reason for this is that CAD has a complex inheritance and etiology…

Quantitative Methods · Quantitative Biology 2016-05-12 Hassan Foroughi Asl

Premature coronary artery disease (PCAD) refers to the early onset of the disease, usually before the age of 55 for men and 65 for women. Coronary Artery Disease (CAD) develops when coronary arteries, the major blood vessels supplying the…

Cardiac magnetic resonance imaging improves on diagnosis of cardiovascular diseases by providing images at high spatiotemporal resolution. Manual evaluation of these time-series, however, is expensive and prone to biased and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 Fabian Isensee , Paul Jaeger , Peter M. Full , Ivo Wolf , Sandy Engelhardt , Klaus H. Maier-Hein

Rare diseases are very difficult to identify among large number of other possible diagnoses. Better availability of patient data and improvement in machine learning algorithms empower us to tackle this problem computationally. In this…

Machine Learning · Computer Science 2016-09-07 Ravi Garg , Shu Dong , Sanjiv Shah , Siddhartha R Jonnalagadda

Cardiovascular diseases are the most common cause of mortality worldwide. Detection of atrial fibrillation (AF) in the asymptomatic stage can help prevent strokes. It also improves clinical decision making through the delivery of suitable…

Signal Processing · Electrical Eng. & Systems 2020-02-14 Faezeh Nejati Hatamian , Nishant Ravikumar , Sulaiman Vesal , Felix P. Kemeth , Matthias Struck , Andreas Maier

Aiming at the latest particle swarm optimization algorithm, this paper proposes an improved Transformer model to improve the accuracy of heart disease prediction and provide a new algorithm idea. We first use three mainstream machine…

Artificial Intelligence · Computer Science 2025-01-08 Jingyuan Yi , Peiyang Yu , Tianyi Huang , Zeqiu Xu
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