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Phylogenetic diversity (PD) depends on sampling intensity, which complicates the comparison of PD between samples of different depth. One approach to dealing with differing sample depth for a given diversity statistic is to rarefy, which…

Populations and Evolution · Quantitative Biology 2015-03-20 David A. Nipperess , Frederick A. Matsen

In a letter published in Molecular Biology Evolution [10], Chen and Zhang argue that the variation of the mutation rate along the Escherichia coli genome that we recently reported [3] cannot be evolutionarily optimised. To support this…

Genomics · Quantitative Biology 2013-05-09 Inigo Martincorena , Nicholas M. Luscombe

More than any other species, humans form social ties to individuals who are neither kin nor mates, and these ties tend to be with similar people. Here, we show that this similarity extends to genotypes. Across the whole genome, friends'…

Genomics · Quantitative Biology 2014-12-05 Nicholas A. Christakis , James H. Fowler

Differential evolution (DE) algorithm with a small population size is called Micro-DE (MDE). A small population size decreases the computational complexity but also reduces the exploration ability of DE by limiting the population diversity.…

Neural and Evolutionary Computing · Computer Science 2017-09-22 Hojjat Salehinejad , Shahryar Rahnamayan , Hamid R. Tizhoosh

In evolutionary processes, population structure has a substantial effect on natural selection. Here, we analyze how motion of individuals affects constant selection in structured populations. Motion is relevant because it leads to changes…

Populations and Evolution · Quantitative Biology 2017-10-10 Madison S. Krieger , Alex McAvoy , Martin A. Nowak

The compact genetic algorithm is an Estimation of Distribution Algorithm for binary optimisation problems. Unlike the standard Genetic Algorithm, no cross-over or mutation is involved. Instead, the compact Genetic Algorithm uses a virtual…

Neural and Evolutionary Computing · Computer Science 2017-08-08 Simon M. Lucas , Jialin Liu , Diego Pérez-Liébana

Chromosomal crossovers play a crucial role in meiotic cell division, as they ensure proper chromosome segregation and increase genetic variability. Experiments have consistently revealed two key observations across species: (i) the number…

Biological Physics · Physics 2025-09-12 Marcel Ernst , Riccardo Rossetto , David Zwicker

We are interested in modelling Darwinian evolution, resulting from the interplay of phenotypic variation and natural selection through ecological interactions. Our models are rooted in the microscopic, stochastic description of a population…

Probability · Mathematics 2016-08-16 Nicolas Champagnat , Régis Ferrière , Sylvie Méléard

In genetic drift of small population, it is well known that even when the ratio of alleles is 0.5, specific genes are fixed in or disappear from the population. It seems the reason why inbreeding is avoided. On the other hand, this…

Populations and Evolution · Quantitative Biology 2018-05-08 Hiroshi Isshiki

The advent of modern genome sequencing techniques allows for a more stringent test of the neutrality hypothesis of Darwinian evolution, where all individuals have the same fitness. Using the individual based model of Wright and Fisher, we…

Populations and Evolution · Quantitative Biology 2017-02-01 Bahram Houchmandzadeh

Modern biological tools have made it possible to unequivocally demonstrate the deep relationship among species in terms of genes and basic molecular mechanisms. In addition, results from genetic, physical and physiological approaches…

Populations and Evolution · Quantitative Biology 2019-03-11 Jacques H. Daniel

How self-incompatibility systems are maintained in plant populations is still a debated issue. Theoretical models predict that self-incompatibility systems break down according to the intensity of inbreeding depression and number of…

Populations and Evolution · Quantitative Biology 2012-02-02 Miguel Navascués , Solenn Stoeckel , Stephanie Mariette

Linked beneficial and deleterious mutations are known to decrease the fixation probability of a favorable mutation in large asexual populations. While the hindering effect of strongly deleterious mutations on adaptive evolution has been…

Populations and Evolution · Quantitative Biology 2022-03-22 Kavita Jain

Lexicase selection and novelty search, two parent selection methods used in evolutionary computation, emphasize exploring widely in the search space more than traditional methods such as tournament selection. However, lexicase selection is…

Neural and Evolutionary Computing · Computer Science 2019-07-04 Lia Jundt , Thomas Helmuth

Consider a genetic locus carrying a strongly beneficial allele which has recently fixed in a large population. As strongly beneficial alleles fix quickly, sequence diversity at partially linked neutral loci is reduced. This phenomenon is…

Populations and Evolution · Quantitative Biology 2007-05-23 P. Pfaffelhuber , A. Studeny

When a population inhabits an inhomogeneous environment, the fitness value of traits can vary with the position in the environment. Gene flow caused by random mating can nevertheless prevent that a sexually reproducing population splits…

Populations and Evolution · Quantitative Biology 2011-05-05 Susanne Schindler , Olaf Breidbach , Juergen Jost

Consider a branching process with a homogeneous reproduction law. Sampling a single cell uniformly from the population at a time $T > 0$ and looking along the sampled cell's ancestral lineage, we find that the reproduction law is…

Populations and Evolution · Quantitative Biology 2022-05-30 David Cheek , Samuel G. G. Johnston

Diversity is an important factor in evolutionary algorithms to prevent premature convergence towards a single local optimum. In order to maintain diversity throughout the process of evolution, various means exist in literature. We analyze…

Neural and Evolutionary Computing · Computer Science 2018-10-31 Thomas Gabor , Lenz Belzner , Claudia Linnhoff-Popien

Transcription factor binding sites vary in their specificity, both within and between species. Binding specificity has a strong impact on the evolution of gene expression, because it determines how easily regulatory interactions are gained…

Populations and Evolution · Quantitative Biology 2013-12-30 Alexander J. Stewart , Joshua B. Plotkin

The current state-of-the-art of population synthesis is reviewed. The field is currently undergoing major revisions with the recognition of several key processes as new critical ingredients. Stochastic effects can artificially enhance or…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-03 Claus Leitherer , Sylvia Ekstrom
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