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We study macroevolutionary dynamics by extending microevolutionary competition models to long time scales. It has been shown that for a general class of competition models, gradual evolutionary change in continuous phenotypes (evolutionary…

Populations and Evolution · Quantitative Biology 2017-02-14 Michael Doebeli , Iaroslav Ispolatov

In large clonal populations, several clones generally compete which results in complex evolutionary and ecological dynamics: experiments show successive selective sweeps of favorable mutations as well as long-term coexistence of multiple…

Populations and Evolution · Quantitative Biology 2019-03-29 Sylvain Billiard , Charline Smadi

We consider the dynamics of a periodic chain of N coupled overdamped particles under the influence of noise, in the limit of large N. Each particle is subjected to a bistable local potential, to a linear coupling with its nearest…

Probability · Mathematics 2007-10-16 Nils Berglund , Bastien Fernandez , Barbara Gentz

Kingman's coalescent is a random tree that arises from classical population genetic models such as the Moran model. The individuals alive in these models correspond to the leaves in the tree and the following two laws of large numbers…

Probability · Mathematics 2014-06-24 Andrej Depperschmidt , Peter Pfaffelhuber , Annika Scheuringer

Positive selection distorts the structure of genealogies and hence alters patterns of genetic variation within a population. Most analyses of these distortions focus on the signatures of hitchhiking due to hard or soft selective sweeps at a…

Populations and Evolution · Quantitative Biology 2012-08-17 Michael M. Desai , Aleksandra M. Walczak , Daniel S. Fisher

In considering evolution of transcribed regions, regulatory modules, and other genomic loci of interest, we are often faced with a situation in which the number of allelic states greatly exceeds the population size. In this limit, the…

Populations and Evolution · Quantitative Biology 2016-07-27 Pavel Khromov , Constantin D. Malliaris , Alexandre V. Morozov

Neural population equations such as neural mass or field models are widely used to study brain activity on a large scale. However, the relation of these models to the properties of single neurons is unclear. Here we derive an equation for…

Neurons and Cognition · Quantitative Biology 2017-04-24 Tilo Schwalger , Moritz Deger , Wulfram Gerstner

The Ancestral Selection Graph (ASG) is an important genealogical process which extends the well-known Kingman coalescent to incorporate natural selection. We show that the number of lineages of the ASG with and without mutation is…

Probability · Mathematics 2020-12-23 Philip A. Hanson , Paul A. Jenkins , Jere Koskela , Dario Spanò

Heterogeneities in environmental conditions often induce corresponding heterogeneities in the distribution of species. In the extreme case of a localized patch of increased growth rates, reproducing populations can become strongly…

Populations and Evolution · Quantitative Biology 2013-01-17 Lukas Geyrhofer , Oskar Hallatschek

We study a model of a population with individuals sampled from different species. The Yule-$\Lambda$ nested coalescent describes the genealogy of the sample when each species merges with another randomly chosen species with a constant rate…

Probability · Mathematics 2024-01-05 Toni Gui

A model is proposed of an infinite population of entities immigrating to a noncompact habitat, in which the newcomers are repelled by the already existing population. The evolution of such a population is described at micro- and mesoscopic…

Dynamical Systems · Mathematics 2018-08-14 Yuri Kozitsky

We consider a stochastic individual-based model of adaptive dynamics for an asexually reproducing population with mutation, with linear birth and death rates, as well as a density-dependent competition. To depict repeating changes of the…

Populations and Evolution · Quantitative Biology 2025-05-28 Manuel Esser , Anna Kraut

Pervasive natural selection can strongly influence observed patterns of genetic variation, but these effects remain poorly understood when multiple selected variants segregate in nearby regions of the genome. Classical population genetics…

Populations and Evolution · Quantitative Biology 2013-06-06 Benjamin H. Good , Aleksandra M. Walczak , Richard A. Neher , Michael M. Desai

We study the dynamics of a population subject to selective pressures, evolving either on RNA neutral networks or in toy fitness landscapes. We discuss the spread and the neutrality of the population in the steady state. Different limits…

Populations and Evolution · Quantitative Biology 2009-11-13 Sumedha , Olivier C Martin , Luca Peliti

I discuss the so-called stochastic individual based model of adaptive dynamics and in particular how different scaling limits can be obtained by taking limits of large populations, small mutation rate, and small effect of single mutations…

Populations and Evolution · Quantitative Biology 2021-07-06 Anton Bovier

We study a one-dimensional spatial population model where the population sizes at each site are chosen according to a translation invariant and ergodic distribution and are uniformly bounded away from 0 and infinity. We suppose that the…

Probability · Mathematics 2019-06-14 Raphaël Forien

Coalescence processes have received a lot of attention in the context of conditional branching processes with fixed population size and non-overlapping generations. Here we focus on similar problems in the context of the standard…

Probability · Mathematics 2017-09-25 Nicolas Grosjean , Thierry Huillet

We consider a model of a population of fixed size $N$ undergoing selection. Each individual acquires beneficial mutations at rate $\mu_N$, and each beneficial mutation increases the individual's fitness by $s_N$. Each individual dies at…

Probability · Mathematics 2015-07-03 Jason Schweinsberg

The genetic diversity of a species is shaped by its recent evolutionary history and can be used to infer demographic events or selective sweeps. Most inference methods are based on the null hypothesis that natural selection is a weak or…

Populations and Evolution · Quantitative Biology 2013-03-05 Richard A. Neher , Oskar Hallatschek

This article is concerned with the long time behavior of neutral genetic population models, with fixed population size. We design an explicit, finite, exact, genealogical tree based representation of stationary populations that holds both…

Probability · Mathematics 2007-05-23 Pierre Del Moral , Laurent Miclo , Frédéric Patras , Sylvain Rubenthaler