English
Related papers

Related papers: Toggling a Genetic Switch Using Reinforcement Lear…

200 papers

A major goal in genomics is to properly capture the complex dynamical behaviors of gene regulatory networks (GRNs). This includes inferring the complex interactions between genes, which can be used for a wide range of genomics analyses,…

Molecular Networks · Quantitative Biology 2023-01-18 Mohammad Alali , Mahdi Imani

We study a genetic regulatory network model developed to demonstrate that genetic robustness can evolve through stabilizing selection for optimal phenotypes. We report preliminary results on whether such selection could result in a…

Molecular Networks · Quantitative Biology 2010-12-07 Volkan Sevim , Per Arne Rikvold

This paper concerns applications of genetic algorithms and genetic programming to tasks for which it is difficult to find a representation that does not map to a highly complex and discontinuous fitness landscape. In such cases the standard…

Neural and Evolutionary Computing · Computer Science 2016-05-06 Michal Gregor , Juraj Spalek

The well-known issue of reconstructing regulatory networks from gene expression measurements has been somewhat disrupted by the emergence and rapid development of single-cell data. Indeed, the traditional way of seeing a gene regulatory…

Molecular Networks · Quantitative Biology 2021-10-01 Ulysse Herbach

The characterisation of quantum networks is fundamental to understanding how energy and information propagates through complex systems, with applications in control, communication, error mitigation and energy transfer. In this work, we…

Quantum Physics · Physics 2025-09-19 Conall J. Campbell , Matthew Mackinnon , Mauro Paternostro , Diana A. Chisholm

Our premise is that autonomous vehicles must optimize communications and motion planning jointly. Specifically, a vehicle must adapt its motion plan staying cognizant of communications rate related constraints and adapt the use of…

Systems and Control · Computer Science 2018-07-31 Mayank K. Pal , Rupali Bhati , Anil Sharma , Sanjit K. Kaul , Saket Anand , P. B. Sujit

Reinforcement learning continuously optimizes decision-making based on real-time feedback reward signals through continuous interaction with the environment, demonstrating strong adaptive and self-learning capabilities. In recent years, it…

Robotics · Computer Science 2024-08-15 Zixiang Wang , Hao Yan , Yining Wang , Zhengjia Xu , Zhuoyue Wang , Zhizhong Wu

Through natural evolution, nervous systems of organisms formed near-optimal structures to express behavior. Here, we propose an effective way to create control agents, by \textit{re-purposing} the function of biological neural circuit…

Neural and Evolutionary Computing · Computer Science 2017-11-10 Mathias Lechner , Radu Grosu , Ramin M. Hasani

This paper proposes a robust control design method using reinforcement-learning for controlling partially-unknown dynamical systems under uncertain conditions. The method extends the optimal reinforcement-learning algorithm with a new…

Systems and Control · Electrical Eng. & Systems 2020-04-17 Phuong D. Ngo , Fred Godtliebsen

The problem of reinforcement learning is considered where the environment or the model undergoes a change. An algorithm is proposed that an agent can apply in such a problem to achieve the optimal long-time discounted reward. The algorithm…

Systems and Control · Electrical Eng. & Systems 2023-04-25 Wuxia Chen , Taposh Banerjee , Jemin George , Carl Busart

This paper studies the robustness of reinforcement learning algorithms to errors in the learning process. Specifically, we revisit the benchmark problem of discrete-time linear quadratic regulation (LQR) and study the long-standing open…

Optimization and Control · Mathematics 2021-03-16 Bo Pang , Zhong-Ping Jiang

As Evolutionary Dynamics moves from the realm of theory into application, algorithms are needed to move beyond simple models. Yet few such methods exist in the literature. Ecological and physiological factors are known to be central to…

Populations and Evolution · Quantitative Biology 2025-05-20 Bryce Allen Bagley , Navin Khoshnan , Claudia K Petritsch

In the field of Autonomous Driving, the system controlling the vehicle can be seen as an agent acting in a complex environment and thus naturally fits into the modern framework of Reinforcement Learning. However, learning to drive can be a…

Artificial Intelligence · Computer Science 2018-11-26 Patrick Klose , Rudolf Mester

Evolutionary strategies have recently been shown to achieve competing levels of performance for complex optimization problems in reinforcement learning. In such problems, one often needs to optimize an objective function subject to a set of…

Neural and Evolutionary Computing · Computer Science 2022-02-23 Youssef Diouane , Aurelien Lucchi , Vihang Patil

In this paper we investigate a neural network model in which weights between computational nodes are modified according to a local learning rule. To determine whether local learning rules are sufficient for learning, we encode the network…

Neural and Evolutionary Computing · Computer Science 2025-12-08 Jonathan Baxter

Genetic learning algorithms are widely used to control ultrafast optical pulse shapes for photo-induced quantum control of atoms and molecules. An unresolved issue is how to use the solutions found by these algorithms to learn about the…

Quantum Physics · Physics 2009-11-10 J. L. White , B. J. Pearson , P. H. Bucksbaum

Control theory has seen recently impactful applications in network science, especially in connections with applications in network medicine. A key topic of research is that of finding minimal external interventions that offer control over…

Molecular Networks · Quantitative Biology 2020-07-10 Victor-Bogdan Popescu , Krishna Kanhaiya , Iulian Năstac , Eugen Czeizler , Ion Petre

Reinforcement learning has emerged as a promising methodology for training robot controllers. However, most results have been limited to simulation due to the need for a large number of samples and the lack of automated-yet-safe data…

Robotics · Computer Science 2018-03-29 Kendall Lowrey , Svetoslav Kolev , Jeremy Dao , Aravind Rajeswaran , Emanuel Todorov

Autonomous agents often require multiple strategies to solve complex tasks, but determining when to switch between strategies remains challenging. This research introduces a reinforcement learning technique to learn switching thresholds…

Machine Learning · Computer Science 2025-12-09 Chris Tava

We develop a continuous-time reinforcement learning framework for a class of singular stochastic control problems without entropy regularization. The optimal singular control is characterized as the optimal singular control law, which is a…

Optimization and Control · Mathematics 2026-05-14 Zongxia Liang , Xiaodong Luo , Xiang Yu