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Mathematical models are crucial for optimizing and controlling chemical processes, yet they often face significant limitations in terms of computational time, algorithm complexity, and development costs. Hybrid models, which combine…

Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. These models can…

Machine Learning · Computer Science 2019-08-06 Qingzhu Gao , Humberto Gonzalez , Parvez Ahammad

The causal assumptions, the study design and the data are the elements required for scientific inference in empirical research. The research is adequately communicated only if all of these elements and their relations are described…

Methodology · Statistics 2015-05-01 Juha Karvanen

An algorithm for automated construction of a sparse Bayesian network given an unstructured probabilistic model and causal domain information from an expert has been developed and implemented. The goal is to obtain a network that explicitly…

Artificial Intelligence · Computer Science 2013-04-08 Sampath Srinivas , Stuart Russell , Alice M. Agogino

This paper outlines a methodology for analyzing the representational support for knowledge-based decision-modeling in a broad domain. A relevant set of inference patterns and knowledge types are identified. By comparing the analysis results…

Artificial Intelligence · Computer Science 2013-03-26 Tze-Yun Leong

Estimating and disentangling epistemic uncertainty, uncertainty that is reducible with more training data, and aleatoric uncertainty, uncertainty that is inherent to the task at hand, is critically important when applying machine learning…

Machine Learning · Computer Science 2024-11-08 Matthew A. Chan , Maria J. Molina , Christopher A. Metzler

For decades, researchers in fields, such as the natural and social sciences, have been verifying causal relationships and investigating hypotheses that are now well-established or understood as truth. These causal mechanisms are properties…

Machine Learning · Computer Science 2019-12-02 Trent Kyono , Mihaela van der Schaar

We present a hierarchical neuro-symbolic control framework that tightly couples a classical symbolic planner with a transformer-based policy to address long-horizon decision-making under uncertainty. At the high level, the planner assembles…

Artificial Intelligence · Computer Science 2025-05-30 Ali Baheri , Cecilia O. Alm

Discovering causal structures with latent variables from observational data is a fundamental challenge in causal discovery. Existing methods often rely on constraint-based, iterative discrete searches, limiting their scalability to large…

Machine Learning · Computer Science 2024-12-02 Parjanya Prashant , Ignavier Ng , Kun Zhang , Biwei Huang

Consider the problem of imputing missing values in a dataset. One the one hand, conventional approaches using iterative imputation benefit from the simplicity and customizability of learning conditional distributions directly, but suffer…

Machine Learning · Statistics 2022-06-17 Daniel Jarrett , Bogdan Cebere , Tennison Liu , Alicia Curth , Mihaela van der Schaar

We present a deep transformation model for probabilistic regression. Deep learning is known for outstandingly accurate predictions on complex data but in regression tasks, it is predominantly used to just predict a single number. This…

Machine Learning · Statistics 2020-04-02 Beate Sick , Torsten Hothorn , Oliver Dürr

Finding a set of nested partitions of a dataset is useful to uncover relevant structure at different scales, and is often dealt with a data-dependent methodology. In this paper, we introduce a general two-step methodology for model-based…

Computation · Statistics 2021-04-22 Etienne Côme , Nicolas Jouvin , Pierre Latouche , Charles Bouveyron

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

We develop a qualitative model of decision making with two aims: to describe how people make simple decisions and to enable computer programs to do the same. Current approaches based on Planning or Decisions Theory either ignore uncertainty…

Artificial Intelligence · Computer Science 2013-02-18 Blai Bonet , Hector Geffner

Local decision rules are commonly understood to be more explainable, due to the local nature of the patterns involved. With numerical optimization methods such as gradient boosting, ensembles of local decision rules can gain good predictive…

Machine Learning · Computer Science 2025-08-27 Xin Du , Subramanian Ramamoorthy , Wouter Duivesteijn , Jin Tian , Mykola Pechenizkiy

Decision Focused Learning has emerged as a critical paradigm for integrating machine learning with downstream optimisation. Despite its promise, existing methodologies predominantly rely on probabilistic models and focus narrowly on task…

Machine Learning · Computer Science 2025-03-21 Keivan Shariatmadar , Neil Yorke-Smith , Ahmad Osman , Fabio Cuzzolin , Hans Hallez , David Moens

One of the most difficult aspects of modeling complex dilemmas in decision-analytic terms is composing a diagram of relevance relations from a set of domain concepts. Decision models in domains such as medicine, however, exhibit certain…

Artificial Intelligence · Computer Science 2013-03-08 John W. Egar , Mark A. Musen

Dynamical models of cognition play an increasingly important role in driving theoretical and experimental research in psychology. Therefore, parameter estimation, model analysis and comparison of dynamical models are of essential…

The increasing polarization in democratic societies is an emergent outcome of political opinion dynamics. Yet, the fundamental mechanisms behind the formation of political opinions, from individual beliefs to collective consensus, remain…

Social and Information Networks · Computer Science 2025-04-04 Valeria Widler , Barbara Kaminska , Andre C. R. Martins , Ivan Puga-Gonzalez

In the drug discovery process, where experiments can be costly and time-consuming, computational models that predict drug-target interactions are valuable tools to accelerate the development of new therapeutic agents. Estimating the…

Machine Learning · Computer Science 2024-07-22 Hannah Rosa Friesacher , Ola Engkvist , Lewis Mervin , Yves Moreau , Adam Arany
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