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Major advances have been made regarding the utilization of artificial intelligence in health care. In particular, deep learning approaches have been successfully applied for automated and assisted disease diagnosis and prognosis based on…

Methodology · Statistics 2020-03-24 Max Westphal , Antonia Zapf , Werner Brannath

Objective: Breast cancer screening is of great significance in contemporary women's health prevention. The existing machines embedded in the AI system do not reach the accuracy that clinicians hope. How to make intelligent systems more…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Jian Dai , Shuge Lei , Licong Dong , Xiaona Lin , Huabin Zhang , Desheng Sun , Kehong Yuan

Heart murmurs are a common manifestation of cardiovascular diseases and can provide crucial clues to early cardiac abnormalities. While most current research methods primarily focus on the accuracy of models, they often overlook other…

Sound · Computer Science 2024-05-08 Zixing Zhang , Tao Pang , Jing Han , Björn W. Schuller

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

Missing data are often dealt with multiple imputation. A crucial part of the multiple imputation process is selecting sensible models to generate plausible values for incomplete data. A method based on posterior predictive checking is…

Computation · Statistics 2026-05-14 Mingyang Cai , Stef van Buuren , Gerko Vink

Neural density estimators have proven remarkably powerful in performing efficient simulation-based Bayesian inference in various research domains. In particular, the BayesFlow framework uses a two-step approach to enable amortized parameter…

Methodology · Statistics 2022-11-10 Marvin Schmitt , Paul-Christian Bürkner , Ullrich Köthe , Stefan T. Radev

Recent research has found that diagnostic performance with Bayesian belief networks is often surprisingly insensitive to imprecision in the numerical probabilities. For example, the authors have recently completed an extensive study in…

Artificial Intelligence · Computer Science 2013-02-18 Max Henrion , Malcolm Pradhan , Brendan del Favero , Kurt Huang , Gregory M. Provan , Paul O'Rorke

Multiple organ failure (MOF) is a severe syndrome with a high mortality rate among Intensive Care Unit (ICU) patients. Early and precise detection is critical for clinicians to make timely decisions. An essential challenge in applying…

Machine Learning · Computer Science 2021-06-23 Xinlu Zhang , Yun Zhao , Rachael Callcut , Linda Petzold

Estimating probability of failure in aerospace systems is a critical requirement for flight certification and qualification. Failure probability estimation involves resolving tails of probability distribution, and Monte Carlo sampling…

Numerical Analysis · Mathematics 2022-09-22 S. Ashwin Renganathan , Vishwas Rao , Ionel M. Navon

The Noisy-Or model is convenient for describing a class of uncertain relationships in Bayesian networks [Pearl 1988]. Pearl describes the Noisy-Or model for Boolean variables. Here we generalize the model to nary input and output variables…

Artificial Intelligence · Computer Science 2013-03-08 Sampath Srinivas

This paper develops a multifidelity method that enables estimation of failure probabilities for expensive-to-evaluate models via information fusion and importance sampling. The presented general fusion method combines multiple probability…

Machine learning models offer the potential to understand diverse datasets in a data-driven way, powering insights into individual disease experiences and ensuring equitable healthcare. In this study, we explore Bayesian inference for…

Machine Learning · Computer Science 2023-11-23 Beatrice Taylor , Cameron Shand , Chris J. D. Hardy , Neil Oxtoby

Deep neural networks are known to be data-driven and label noise can have a marked impact on model performance. Recent studies have shown great robustness to classic image recognition even under a high noisy rate. In medical applications,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-23 Lie Ju , Xin Wang , Lin Wang , Dwarikanath Mahapatra , Xin Zhao , Mehrtash Harandi , Tom Drummond , Tongliang Liu , Zongyuan Ge

Measurement error in multinomial data is a well-known and well-studied inferential problem that is encountered in many fields, including engineering, biomedical and omics research, ecology, finance, official statistics, and social sciences.…

Methodology · Statistics 2024-10-15 Matthew D. Koslovsky , Andee Kaplan , Victoria A. Terranova , Mevin B. Hooten

Deep neural networks have been successful in diverse discriminative classification tasks, although, they are poorly calibrated often assigning high probability to misclassified predictions. Potential consequences could lead to…

Machine Learning · Statistics 2020-10-06 John Mitros , Arjun Pakrashi , Brian Mac Namee

Multi-modal ophthalmic image classification plays a key role in diagnosing eye diseases, as it integrates information from different sources to complement their respective performances. However, recent improvements have mainly focused on…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Ke Zou , Tian Lin , Zongbo Han , Meng Wang , Xuedong Yuan , Haoyu Chen , Changqing Zhang , Xiaojing Shen , Huazhu Fu

The noisy-or and its generalization noisy-max have been utilized to reduce the complexity of knowledge acquisition. In this paper, we present a new representation of noisy-max that allows for efficient inference in general Bayesian…

Artificial Intelligence · Computer Science 2013-01-30 Masami Takikawa , Bruce D'Ambrosio

Computational cardiovascular models are promising tools for clinical decision support, particularly in complex conditions, such as intraoperative hypotension (IOH). IOH arises from different mechanisms, making treatment selection…

Medical Physics · Physics 2025-09-19 Jan-Niklas Thiel , Marko Zlicar , Ulrich Steinseifer , Borut Kirn , Michael Neidlin

We derive fundamental bounds on the maximal achievable precision in multiparameter noisy quantum metrology, valid under the most general entanglement-assisted adaptive strategy, which are tighter than the bounds obtained by a direct use of…

Quantum Physics · Physics 2022-05-27 Francesco Albarelli , Rafal Demkowicz-Dobrzanski

Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Akshay Bhagwan Sonawane , Lena D. Swamikannan , Lakshman Tamil