English
Related papers

Related papers: Enumeration of RNA complexes via random matrix the…

200 papers

We give recurrence relations for the enumeration of symmetric elements within four classes of arc diagrams corresponding to certain involutions and set partitions whose blocks contain no consecutive integers. These arc diagrams are…

Combinatorics · Mathematics 2023-04-19 Juan B. Gil , Luis E. Lopez

We analyze a microscopic RNA model, which includes two widely used models as limiting cases, namely it contains terms for bond as well as for stacking energies. We numerically investigate possible changes in the qualitative and quantitative…

Quantitative Methods · Quantitative Biology 2009-11-10 Bernd Burghardt , Alexander K. Hartmann

The topology of many real complex networks has been conjectured to be embedded in hidden metric spaces, where distances between nodes encode their likelihood of being connected. Besides of providing a natural geometrical interpretation of…

Physics and Society · Physics 2017-01-23 Antoine Allard , M. Ángeles Serrano , Guillermo García-Pérez , Marián Boguñá

Nucleic acid sequence design via codon optimization is a fundamental task with applications across synthetic biology, mRNA therapeutics, and vaccine design. Given a target protein, it is a major open challenge to navigate the…

Quantitative Methods · Quantitative Biology 2026-04-22 Mark Fornace , Christina Wuyan Wang , Michael Lindsey

We solve the random energy model when the energies of the configurations take only integer values. In the thermodynamic limit, the average overlaps remain size dependent and oscillate as the system size increases. While the extensive part…

Disordered Systems and Neural Networks · Physics 2022-06-22 Bernard Derrida , Peter Mottishaw

RNA design is the search for a sequence or set of sequences that will fold into predefined structures, also known as the inverse problem of RNA folding. While numerous RNA design methods have been invented to find sequences capable of…

Biomolecules · Quantitative Biology 2024-08-13 Tianshuo Zhou , Wei Yu Tang , David H. Mathews , Liang Huang

The combinatorics of RNA plays a central role in biology. Mathematical biologists have several commonly-used models for RNA: words in a fixed alphabet (representing the primary sequence of nucleotides) and plane trees (representing the…

Combinatorics · Mathematics 2017-06-23 Frances Black , Elizabeth Drellich , Julianna Tymoczko

We consider the inverse-folding problem for RNA secondary structures: for a given (pseudo-knot-free) secondary structure find a sequence that has that structure as its ground state. If such a sequence exists, the structure is called…

Biological Physics · Physics 2015-06-26 Bernd Burghardt , Alexander K. Hartmann

An efficient numerical framework is presented for modeling viscoelasticity and permanent set of polymers. It is based on the hereditary integral form of transient network theory, in which polymer chains belong to distinct networks each with…

Computational Engineering, Finance, and Science · Computer Science 2025-06-27 Stephen T. Castonguay , Joshua B. Fernandes , Michael A. Puso , Sylvie Aubry

In this paper, we establish a connection between the formalism of $\mathcal{R}$-transforms for non-Hermitian random matrices and the framework of spherical integrals, using the replica method. This connection was previously proved in the…

Disordered Systems and Neural Networks · Physics 2026-05-15 Pierre Bousseyroux , Marc Potters

Random contractions (sub-unitary random matrices) appear naturally when considering quantized chaotic maps within a general theory of open linear stationary systems with discrete time. We analyze statistical properties of complex…

Chaotic Dynamics · Physics 2009-10-31 Yan V. Fyodorov , H. -J. Sommmers

We introduce a family of polynomials, which arise in three distinct ways: in the large $N$ expansion of a matrix integral, as a weighted enumeration of factorisations of permutations, and via the topological recursion. More explicitly, we…

Combinatorics · Mathematics 2025-07-02 Xavier Coulter , Norman Do , Ellena Moskovsky

Simulated nucleotide sequences are widely used in theoretical and empirical molecular evolution studies. Conventional simulators generally use fixed parameter time-homogeneous Markov model for sequence evolution. In this work, we use the…

Populations and Evolution · Quantitative Biology 2009-12-14 Sheng Guo , Li-San Wang , Junhyong Kim

Given a chain complex with the only modification that each cell of the complex has a probability distribution assigned. We will call this complex - a random complex and what should be understood in practice, is that we have a classical…

Algebraic Topology · Mathematics 2016-11-25 Todor Todorov

We derive exact matrix integral representations for different sums over partitions. The characteristic feature of all obtained matrix models is the presence of logarithmic (or, vice versa, exponential) terms in the potential. Our derivation…

High Energy Physics - Theory · Physics 2011-07-19 A. Alexandrov

The evolution of the genome has led to very sophisticated and complex regulation. Because of the abundance of non-coding RNA (ncRNA) in the cell, different species will promiscuously associate with each other, suggesting collective dynamics…

Molecular Networks · Quantitative Biology 2018-05-16 J. M. Deutsch

Consider a random word $X^n=(X_1,\ldots ,X_n)$ in an alphabet consisting of $4$ letters, with the letters viewed either as $A$, $U$, $G$ and $C$ (i.e., nucleotides in an RNA sequence) or $\alpha$, $\bar{\alpha}$, $\beta$ and $\bar{\beta}$…

Group Theory · Mathematics 2022-01-20 Siddhartha Gadgil , Manjunath Krishnapur

We investigate tensor products of random matrices, and show that independence of entries leads asymptotically to $\varepsilon$-free independence, a mixture of classical and free independence studied by M{\l}otkowski and by Speicher and…

Operator Algebras · Mathematics 2021-03-24 Ian Charlesworth , Benoît Collins

This work concerns finite free complexes over commutative noetherian rings, in particular over group algebras of elementary abelian groups. The main contribution is the construction of complexes such that the total rank of their underlying…

Commutative Algebra · Mathematics 2018-05-11 Srikanth B. Iyengar , Mark E. Walker

We present the diagrammatic technique for calculating the free energy of the matrix eigenvalue model (the model with arbitrary power $\beta$ by the Vandermonde determinant) to all orders of 1/N expansion in the case where the limiting…

Mathematical Physics · Physics 2010-02-03 Leonid Chekhov , Bertrand Eynard