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Glioblastoma multiform carries a dismal prognosis with poor response to gold standard treatment. Innovative data analysis methods have been developed to characterize tumor genomic expression with histologic features. In a clinical setting,…

Quantitative Methods · Quantitative Biology 2020-03-06 Emily Diller , Jason Parker

Finding, identifying and segmenting suspicious cancer metastasized lymph nodes from 3D multi-modality imaging is a clinical task of paramount importance. In radiotherapy, they are referred to as Lymph Node Gross Tumor Volume (GTVLN).…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Zhuotun Zhu , Dakai Jin , Ke Yan , Tsung-Ying Ho , Xianghua Ye , Dazhou Guo , Chun-Hung Chao , Jing Xiao , Alan Yuille , Le Lu

In this article, we present a graph-based method using a cubic template for volumetric segmentation of vertebrae in magnetic resonance imaging (MRI) acquisitions. The user can define the degree of deviation from a regular cube via a…

Computer Vision and Pattern Recognition · Computer Science 2015-06-19 Robert Schwarzenberg , Bernd Freisleben , Christopher Nimsky , Jan Egger

Glioblastoma Multiforme (GBM) is a highly aggressive brain tumour with limited therapeutic options and poor prognosis. This study presents a mathematical framework to investigate the efficacy of immunotherapy strategies based on cytotoxic…

Populations and Evolution · Quantitative Biology 2025-12-23 Francesca Ballatore , Lorenzo Scolaris , Chiara Giverso

This article presents an evaluation of biliary tract segmentation methods used for 3D reconstruction, which may be very usefull in various critical interventions, such as endoscopic retrograde cholangiopancreatography (ERCP), using the 3D…

Glioma is a common type of brain tumor, and accurate detection of it plays a vital role in the diagnosis and treatment process. Despite advances in medical image analyzing, accurate tumor segmentation in brain magnetic resonance (MR) images…

Image and Video Processing · Electrical Eng. & Systems 2020-02-27 Fateme Mostafaie , Reihaneh Teimouri , Zahra Nabizadeh , Nader Karimi , Shadrokh Samavi

Automated segmentation tools often encounter accuracy and adaptability issues when applied to images of different pathology. The purpose of this study is to explore the feasibility of building a workflow to efficiently route images to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Peilong Wang , Timothy L. Kline , Andy D. Missert , Cole J. Cook , Matthew R. Callstrom , Alex Chan , Robert P. Hartman , Zachary S. Kelm , Panagiotis Korfiatis

This paper presents a generic framework for the numerical simulation of transformation-diffusion processes in complex volume geometric shapes. This work follows a previous one devoted to the simulation of microbial degradation of organic…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Monga Olivier , Hecht Frédéric , Moto Serge , Klai Mouad , Mbe Bruno , Dias Jorge , Garnier Patricia , Pot Valérie

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Xiaoyu Shi , Shurong Chai , Yinhao Li , Jingliang Cheng , Jie Bai , Guohua Zhao , Yen-Wei Chen

In this paper we consider the influence of intercellular communication on the development and progression of Glioblastoma Multiforme (GBM), a grade IV malignant glioma which is defined by an interplay Grow i.e. self renewal and Go i.e.…

Neurons and Cognition · Quantitative Biology 2021-05-03 Hamdan Awan , Andreani Odysseos , Niovi Nicolaou , Sasitharan Balasubramaniam

Accurate brain tumor segmentation is crucial for neuro-oncology diagnosis and treatment planning. Deep learning methods have made significant progress, but automatic segmentation still faces challenges, including tumor morphological…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Mingda Zhang

In this work, we aim to predict the survival time (ST) of glioblastoma (GBM) patients undergoing different treatments based on preoperative magnetic resonance (MR) scans. The personalized and precise treatment planning can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Xiaofeng Liu , Nadya Shusharina , Helen A Shih , C. -C. Jay Kuo , Georges El Fakhri , Jonghye Woo

Pediatric brain tumors, particularly gliomas, represent a significant cause of cancer related mortality in children with complex infiltrative growth patterns that complicate treatment. Early, accurate segmentation of these tumors in…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Harish Thangaraj , Diya Katariya , Eshaan Joshi , Sangeetha N

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Gliomas, the most prevalent primary brain tumors, require precise segmentation for diagnosis and treatment planning. However, this task poses significant challenges, particularly in the African population, were limited access to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Mohannad Barakat , Noha Magdy , Jjuuko George William , Ethel Phiri , Raymond Confidence , Dong Zhang , Udunna C Anazodo

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Andrei Iantsen

Our objective is the calibration of mathematical tumor growth models from a single multiparametric scan. The target problem is the analysis of preoperative Glioblastoma (GBM) scans. To this end, we present a fully automatic tumor-growth…

Medical Physics · Physics 2020-01-28 Klaudius Scheufele , Shashank Subramanian , George Biros

Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ramy A. Zeineldin , Mohamed E. Karar , Oliver Burgert , Franziska Mathis-Ullrich

Volumetric biomedical microscopy has the potential to increase the diagnostic information extracted from clinical tissue specimens and improve the diagnostic accuracy of both human pathologists and computational pathology models.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Cheng Jiang , Alexander Gedeon , Yiwei Lyu , Eric Landgraf , Yufeng Zhang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Honglak Lee , Todd Hollon

Glioblastoma Multiforme (GBM) is a malignant brain cancer forming around 48% of al brain and Central Nervous System (CNS) cancers. It is estimated that annually over 13,000 deaths occur in the US due to GBM, making it crucial to have early…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Sauman Das