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In the postgenome era many efforts have been dedicated to systematically elucidate the complex web of interacting genes and proteins. These efforts include experimental and computational methods. Microarray technology offers an opportunity…

Molecular Networks · Quantitative Biology 2009-08-04 L. Diambra

As machine learning tasks continue to evolve, the trend has been to gather larger datasets and train increasingly larger models. While this has led to advancements in accuracy, it has also escalated computational costs to unsustainable…

Machine Learning · Computer Science 2024-06-03 Mohammad Jafari , Yimeng Zhang , Yihua Zhang , Sijia Liu

The objective of this paper is to define an effective strategy for building an ensemble of Genetic Programming (GP) models. Ensemble methods are widely used in machine learning due to their features: they average out biases, they reduce the…

Neural and Evolutionary Computing · Computer Science 2019-06-14 Mauro Castelli , Ivo Gonçalves , Luca Manzoni , Leonardo Vanneschi

Selectivity estimation - the problem of estimating the result size of queries - is a fundamental problem in databases. Accurate estimation of query selectivity involving multiple correlated attributes is especially challenging. Poor…

Databases · Computer Science 2019-06-19 Shohedul Hasan , Saravanan Thirumuruganathan , Jees Augustine , Nick Koudas , Gautam Das

In drug discovery, highly automated high-throughput laboratories are used to screen a large number of compounds in search of effective drugs. These experiments are expensive, so one might hope to reduce their cost by only experimenting on a…

Machine Learning · Computer Science 2025-04-15 Ihor Neporozhnii , Julien Roy , Emmanuel Bengio , Jason Hartford

Major complications arise from the recent increase in the amount of high-dimensional data, including high computational costs and memory requirements. Feature selection, which identifies the most relevant and informative attributes of a…

Incorporating feature selection into a classification or regression method often carries a number of advantages. In this paper we formalize feature selection specifically from a discriminative perspective of improving…

Machine Learning · Computer Science 2013-01-18 Tony S. Jebara , Tommi S. Jaakkola

Machine learning problems involving sparse datasets may benefit from the use of convolutional neural networks if the numbers of samples and features are very large. Such datasets are increasingly more frequently encountered in a variety of…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Baris Kanber

Recognition of objects with subtle differences has been used in many practical applications, such as car model recognition and maritime vessel identification. For discrimination of the objects in fine-grained detail, we focus on deep…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Kaan Karaman , Erhan Gundogdu , Aykut Koc , A. Aydin Alatan

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

It is impossible today to pretend that the practice of machine learning is always compatible with the idea that training and testing data follow the same distribution. Several authors have recently used ensemble techniques to show how…

Machine Learning · Computer Science 2025-03-03 Jianyu Zhang , Léon Bottou

Stratifying cancer patients based on their gene expression levels allows improving diagnosis, survival analysis and treatment planning. However, such data is extremely highly dimensional as it contains expression values for over 20000 genes…

As discussed in previous studies, the efficacy of evolutionary or reinforcement learning algorithms for continuous control optimization can be enhanced by including a neural module dedicated to feature extraction trained through…

Machine Learning · Computer Science 2021-06-09 Nicola Milano , Stefano Nolfi

While variable selection is essential to optimize the learning complexity by prioritizing features, automating the selection process is preferred since it requires laborious efforts with intensive analysis otherwise. However, it is not an…

Machine Learning · Computer Science 2019-10-29 Makiya Nakashima , Alex Sim , Youngsoo Kim , Jonghyun Kim , Jinoh Kim

Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of…

Quantitative Methods · Quantitative Biology 2017-05-23 Peng Yang

Machine learning has gained widespread attention as a powerful tool to identify structure in complex, high-dimensional data. However, these techniques are ostensibly inapplicable for experimental systems where data is scarce or expensive to…

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

In the field of functional genomics, the analysis of gene expression profiles through Machine and Deep Learning is increasingly providing meaningful insight into a number of diseases. The paper proposes a novel algorithm to perform Feature…

Genomics · Quantitative Biology 2023-03-31 Carlo Adornetto , Gianluigi Greco

Discovery of diagnostic and prognostic molecular markers is important and actively pursued the research field in cancer research. For complex diseases, this process is often performed using Machine Learning. The current study compares two…

Genomics · Quantitative Biology 2020-04-30 Aneta Polewko-Klim , Witold R. Rudnicki

Probabilistic mixture models have been widely used for different machine learning and pattern recognition tasks such as clustering, dimensionality reduction, and classification. In this paper, we focus on trying to solve the most common…

Machine Learning · Computer Science 2020-04-08 Gustavo A Valencia-Zapata , Daniel Mejia , Gerhard Klimeck , Michael Zentner , Okan Ersoy
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