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Deep sequencing has enabled the investigation of a wide range of environmental microbial ecosystems, but the high memory requirements for {\em de novo} assembly of short-read shotgun sequencing data from these complex populations are an…

Genomics · Quantitative Biology 2015-06-03 Jason Pell , Arend Hintze , Rosangela Canino-Koning , Adina Howe , James M. Tiedje , C. Titus Brown

The de Bruijn graph plays an important role in bioinformatics, especially in the context of de novo assembly. However, the representation of the de Bruijn graph in memory is a computational bottleneck for many assemblers. Recent papers…

Quantitative Methods · Quantitative Biology 2014-10-07 Rayan Chikhi , Antoine Limasset , Shaun Jackman , Jared Simpson , Paul Medvedev

De Bruijn graph is one of the most important data structures used in de-novo genome assembly algorithms, especially for NGS data. There is a growing need for parallel data structures and algorithms due to the increasing number of cores in…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-08 Daniel Górniak , Robert Nowak

This paper presents new alternatives to the well-known Bloom filter data structure. The Bloom filter, a compact data structure supporting set insertion and membership queries, has found wide application in databases, storage systems, and…

Massively parallel DNA sequencing technologies are revolutionizing genomics research. Billions of short reads generated at low costs can be assembled for reconstructing the whole genomes. Unfortunately, the large memory footprint of the…

Data Structures and Algorithms · Computer Science 2012-07-17 Yang Li , Pegah Kamousi , Fangqiu Han , Shengqi Yang , Xifeng Yan , Subhash Suri

A Bloom filter is a method for reducing the space (memory) required for representing a set by allowing a small error probability. In this paper we consider a \emph{Sliding Bloom Filter}: a data structure that, given a stream of elements,…

Data Structures and Algorithms · Computer Science 2013-10-10 Moni Naor , Eylon Yogev

Recently, Marcus et al. (Bioinformatics 2014) proposed to use a compressed de Bruijn graph to describe the relationship between the genomes of many individuals/strains of the same or closely related species. They devised an $O(n \log g)$…

Data Structures and Algorithms · Computer Science 2016-02-11 Timo Beller , Enno Ohlebusch

de Bruijn graph-based algorithms are one of the two most widely used approaches for de novo genome assembly. A major limitation of this approach is the large computational memory space requirement to construct the de Bruijn graph, which…

Data Structures and Algorithms · Computer Science 2011-07-11 Chengxi Ye , Zhanshan Sam Ma , Charles H. Cannon , Mihai Pop , Douglas W. Yu

Bloom filters are widely used data structures that compactly represent sets of elements. Querying a Bloom filter reveals if an element is not included in the underlying set or is included with a certain error rate. This membership testing…

Databases · Computer Science 2022-08-08 Angjela Davitkova , Damjan Gjurovski , Sebastian Michel

This paper presents a novel method for efficient image retrieval, based on a simple and effective hashing of CNN features and the use of an indexing structure based on Bloom filters. These filters are used as gatekeepers for the database of…

Multimedia · Computer Science 2016-05-04 Andrea Salvi , Simone Ercoli , Marco Bertini , Alberto Del Bimbo

Bloom filters are a fundamental data structure for approximate membership queries, with applications ranging from data analytics to databases and genomics. Several variants have been proposed to accommodate parallel architectures. GPUs,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-12-18 Daniel Jünger , Kevin Kristensen , Yunsong Wang , Xiangyao Yu , Bertil Schmidt

The merging of succinct data structures is a well established technique for the space efficient construction of large succinct indexes. In the first part of the paper we propose a new algorithm for merging succinct representations of de…

Data Structures and Algorithms · Computer Science 2021-07-13 Lavinia Egidi , Felipe A. Louza , Giovanni Manzini

We propose a new algorithm for merging succinct representations of de Bruijn graphs introduced in [Bowe et al. WABI 2012]. Our algorithm is based on the lightweight BWT merging approach by Holt and McMillan [Bionformatics 2014, ACM-BCB…

Data Structures and Algorithms · Computer Science 2020-09-10 Lavinia Egidi , Felipe A. Louza , Giovanni Manzini

Motivation: Second generation sequencing technology makes it feasible for many researches to obtain enough sequence reads to attempt the de novo assembly of higher eukaryotes (including mammals). De novo assembly not only provides a tool…

Genomics · Quantitative Biology 2010-08-17 Thomas C Conway , Andrew J Bromage

We present a method that uses a Bloom filter transform to preprocess data for machine learning. Each sample is encoded into a compact bit-array representation using hash-based encoding, producing a fixed-length feature space that reduces…

Machine Learning · Computer Science 2026-05-11 John Cartmell , Mihaela Cardei , Ionut Cardei

A Bloom Filter is a probabilistic data structure designed to check, rapidly and memory-efficiently, whether an element is present in a set. It has been vastly used in various computing areas and several variants, allowing deletions, dynamic…

Data Structures and Algorithms · Computer Science 2023-06-13 Ana Rodrigues , Ariel Shtul , Carlos Baquero , Paulo Sérgio Almeida

The formal version of our work has been published in BMC Bioinformatics and can be found here: http://www.biomedcentral.com/1471-2105/13/S6/S1 Motivation: To tackle the problem of huge memory usage associated with de Bruijn graph-based…

Data Structures and Algorithms · Computer Science 2013-01-10 Chengxi Ye , Charles H. Cannon , Zhanshan Sam Ma , Douglas W. Yu , Mihai Pop

A Bloom filter is a memory-efficient data structure for approximate membership queries used in numerous fields of computer science. Recently, learned Bloom filters that achieve better memory efficiency using machine learning models have…

Data Structures and Algorithms · Computer Science 2023-10-31 Atsuki Sato , Yusuke Matsui

De Bruijn graphs are essential for sequencing data analysis and must be efficiently constructed and stored for large-scale population studies. They also need to be dynamic to allow updates such as adding or removing edges and nodes.…

Data Structures and Algorithms · Computer Science 2024-06-19 Riccardo Nigrelli

Applications involving telecommunication call data records, web pages, online transactions, medical records, stock markets, climate warning systems, etc., necessitate efficient management and processing of such massively exponential amount…

Information Retrieval · Computer Science 2012-12-18 Suman K. Bera , Sourav Dutta , Ankur Narang , Souvik Bhattacherjee
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