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Seamless phase II/III trials have become a cornerstone of modern drug development, offering a means to accelerate evaluation while maintaining statistical rigor. However, most existing inference procedures are model-based, designed…

Methodology · Statistics 2025-12-17 Kun Yi , Lucy Xia

For linear regression models who are not exactly sparse in the sense that the coefficients of the insignificant variables are not exactly zero, the working models obtained by a variable selection are often biased. Even in sparse cases,…

Methodology · Statistics 2014-07-17 Lu Lin , Lixing Zhu , Yujie Gai

Existing regression models tend to fall short in both accuracy and uncertainty estimation when the label distribution is imbalanced. In this paper, we propose a probabilistic deep learning model, dubbed variational imbalanced regression…

Machine Learning · Computer Science 2024-11-12 Ziyan Wang , Hao Wang

Randomized smoothing is a widely adopted technique for optimizing nonsmooth objective functions. However, its efficiency analysis typically relies on global Lipschitz continuity, a condition rarely met in practical applications. To address…

Optimization and Control · Mathematics 2025-09-10 Jingfan Xia , Zhenwei Lin , Qi Deng

We present an adaptive smoother for linear state-space models with unknown process and measurement noise covariances. The proposed method utilizes the variational Bayes technique to perform approximate inference. The resulting smoother is…

Systems and Control · Computer Science 2023-07-19 Tohid Ardeshiri , Emre Özkan , Umut Orguner , Fredrik Gustafsson

We propose regularizing the empirical loss for semi-supervised learning by acting on both the input (data) space, and the weight (parameter) space. We show that the two are not equivalent, and in fact are complementary, one affecting the…

Machine Learning · Computer Science 2018-05-24 Safa Cicek , Stefano Soatto

We study a linear high-dimensional regression model in a semi-supervised setting, where for many observations only the vector of covariates $X$ is given with no response $Y$. We do not make any sparsity assumptions on the vector of…

Statistics Theory · Mathematics 2021-09-03 Ilan Livne , David Azriel , Yair Goldberg

Traditional inference in cointegrating regressions requires tuning parameter choices to estimate a long-run variance parameter. Even in case these choices are "optimal", the tests are severely size distorted. We propose a novel…

Econometrics · Economics 2025-10-10 Karsten Reichold , Carsten Jentsch

This paper considers statistical inference for the explained variance $\beta^{\intercal}\Sigma \beta$ under the high-dimensional linear model $Y=X\beta+\epsilon$ in the semi-supervised setting, where $\beta$ is the regression vector and…

Methodology · Statistics 2020-12-01 T. Tony Cai , Zijian Guo

This study introduces Variational Automatic Relevance Determination (VARD), a novel approach tailored for fitting sparse additive regression models in high-dimensional settings. VARD distinguishes itself by its ability to independently…

Methodology · Statistics 2024-11-04 Zihe Liu , Diptarka Saha , Feng Liang

We study general singular value shrinkage estimators in high-dimensional regression and classification, when the number of features and the sample size both grow proportionally to infinity. We allow models with general covariance matrices…

Statistics Theory · Mathematics 2020-04-01 Panagiotis Lolas

We consider Bayesian inverse problems arising in data assimilation for dynamical systems governed by partial and stochastic partial differential equations. The space-time dependent field is inferred jointly with static parameters of the…

Computation · Statistics 2026-03-20 Baptiste Simandoux , Nikolas Kantas , Dan Crisan

A basis expansion with regularization methods is much appealing to the flexible or robust nonlinear regression models for data with complex structures. When the underlying function has inhomogeneous smoothness, it is well known that…

Methodology · Statistics 2021-02-02 Daeju Kim , Shuichi Kawano , Yoshiyuki Ninomiya

Non-parametric inference for functional data over two-dimensional domains entails additional computational and statistical challenges, compared to the one-dimensional case. Separability of the covariance is commonly assumed to address these…

Methodology · Statistics 2021-03-19 Tomas Masak , Tomas Rubin , Victor Panaretos

It is well-known that the reparameterisation gradient estimator, which exhibits low variance in practice, is biased for non-differentiable models. This may compromise correctness of gradient-based optimisation methods such as stochastic…

Machine Learning · Computer Science 2024-02-21 Dominik Wagner , Basim Khajwal , C. -H. Luke Ong

The order of smoothness chosen in nonparametric estimation problems is critical. This choice balances the tradeoff between model parsimony and data overfitting. The most common approach used in this context is cross-validation. However,…

Methodology · Statistics 2015-10-13 Daniel Taylor-Rodriguez , Sujit Ghosh

We propose a new procedure for inference on optimal treatment regimes in the model-free setting, which does not require to specify an outcome regression model. Existing model-free estimators for optimal treatment regimes are usually not…

Methodology · Statistics 2020-07-06 Yunan Wu , Lan Wang

Recent studies have shown that many nonconvex machine learning problems satisfy a generalized-smooth condition that extends beyond traditional smooth nonconvex optimization. However, the existing algorithms are not fully adapted to such…

Optimization and Control · Mathematics 2025-10-03 Yufeng Yang , Erin Tripp , Yifan Sun , Shaofeng Zou , Yi Zhou

We consider applying stochastic approximation (SA) methods to solve nonsmooth variational inclusion problems. Existing studies have shown that the averaged iterates of SA methods exhibit asymptotic normality, with an optimal limiting…

Machine Learning · Statistics 2025-08-13 Liwei Jiang , Abhishek Roy , Krishna Balasubramanian , Damek Davis , Dmitriy Drusvyatskiy , Sen Na

We consider the problem of statistical inference for ranking data, specifically rank aggregation, under the assumption that samples are incomplete in the sense of not comprising all choice alternatives. In contrast to most existing methods,…

Machine Learning · Statistics 2017-12-05 Mohsen Ahmadi Fahandar , Eyke Hüllermeier , Inés Couso