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Evolutionary modeling applications are the best way to provide full information to support in-depth understanding of evaluation of organisms. These applications mainly depend on identifying the evolutionary history of existing organisms and…

Computational Engineering, Finance, and Science · Computer Science 2018-06-01 Sara Shehab , Sameh Abdulah , Arabi E. Keshk

We theorize that phylogenetic profiles provide a quantitative method that can relate the structural and functional properties of proteins, as well as their evolutionary relationships. A key feature of phylogenetic profiles is the…

Quantitative Methods · Quantitative Biology 2009-11-04 Yoojin Hong , Jaewoo Kang , Dongwon Lee , Randen L. Patterson , Damian B. van Rossum

High-utility sequential pattern mining is an emerging topic in the field of Knowledge Discovery in Databases. It consists of discovering subsequences having a high utility (importance) in sequences, referred to as high-utility sequential…

State-space models (SSMs) have recently attention as an efficient alternative to computationally expensive attention-based models for sequence modeling. They rely on linear recurrences to integrate information over time, enabling fast…

Machine Learning · Computer Science 2026-01-01 Mahdi Karami , Ali Behrouz , Peilin Zhong , Razvan Pascanu , Vahab Mirrokni

In sequence-based predictions, conventionally an input sequence is represented by a multiple sequence alignment (MSA) or a representation derived from MSA, such as a position-specific scoring matrix. Recently, inspired by the development in…

Quantitative Methods · Quantitative Biology 2021-10-18 Nabil Ibtehaz , Daisuke Kihara

In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Meilong Xu , Xiaoling Hu , Shahira Abousamra , Chen Li , Chao Chen

Multivariate time series forecasting with hierarchical structure is widely used in real-world applications, e.g., sales predictions for the geographical hierarchy formed by cities, states, and countries. The hierarchical time series (HTS)…

Machine Learning · Computer Science 2023-10-10 Fan Zhou , Chen Pan , Lintao Ma , Yu Liu , Shiyu Wang , James Zhang , Xinxin Zhu , Xuanwei Hu , Yunhua Hu , Yangfei Zheng , Lei Lei , Yun Hu

We introduce a new heuristic for the multiple alignment of a set of sequences. The heuristic is based on a set cover of the residue alphabet of the sequences, and also on the determination of a significant set of blocks comprising…

Quantitative Methods · Quantitative Biology 2007-05-23 A. H. L. Porto , V. C. Barbosa

Multiple sequence alignment (MSA) data play a crucial role in the study of protein mutations, with contact prediction being a notable application. Existing methods are often model-based or algorithmic and typically do not incorporate…

Methodology · Statistics 2026-01-23 Fan Yang , Zhao Ren , Wen Zhou , Kejue Jia , Robert Jernigan

Trajectory analysis is not only about obtaining movement data, but it is also of paramount importance in understanding the pattern in which an object moves through space and time, as well as in predicting its next move. Due to the…

Machine Learning · Computer Science 2025-06-26 Chanuka Don Samarasinghage , Dhruv Gulabani

This paper introduces a novel framework for enhancing Random Forest classifiers by integrating probabilistic feature sampling and hyperparameter tuning via Simulated Annealing. The proposed framework exhibits substantial advancements in…

Machine Learning · Computer Science 2025-11-12 Kowshik Balasubramanian , Andre Williams , Ismail Butun

Modern genomic analyses increasingly rely on pangenomes, that is, representations of the genome of entire populations. The simplest representation of a pangenome is a set of individual genome sequences. Compared to e.g. sequence graphs,…

Genomics · Quantitative Biology 2025-11-25 Jannik Olbrich , Enno Ohlebusch

In recent years, multi-view multi-label learning (MVML) has attracted extensive attention due to its close alignment to real-world scenarios. Information-theoretic methods have gained prominence for learning nonlinear correlations. However,…

Machine Learning · Computer Science 2026-03-04 Cheng Peng , Yonghao Li , Wanfu Gao , Jie Wen , Weiping Ding

Developing an MR sequence is challenging and remains largely constrained by human intuition. Recently, AI-driven approaches have been proposed; however, most require an initial sequence for parameter optimization or extensive training…

Artificial Intelligence · Computer Science 2026-04-17 Rokgi Hong , Hongjun An , Sooyeon Ji , Jongho Lee

The automatic assignment of species information to the corresponding genes in a research article is a critically important step in the gene normalization task, whereby a gene mention is normalized and linked to a database record or…

Computation and Language · Computer Science 2022-10-17 Ling Luo , Chih-Hsuan Wei , Po-Ting Lai , Qingyu Chen , Rezarta Islamaj Doğan , Zhiyong Lu

Attention mechanism in sequence-to-sequence models is designed to model the alignments between acoustic features and output tokens in speech recognition. However, attention weights produced by models trained end to end do not always…

Audio and Speech Processing · Electrical Eng. & Systems 2022-04-27 Gene-Ping Yang , Hao Tang

Placing signal templates (grid points) as efficiently as possible to cover a multi-dimensional parameter space is crucial in computing-intensive matched-filtering searches for gravitational waves, but also in similar searches in other…

Instrumentation and Methods for Astrophysics · Physics 2015-06-23 Henning Fehrmann , Holger J. Pletsch

A valuable step in the modeling of multiscale dynamical systems in fields such as computational chemistry, biology, materials science and more, is the representative sampling of the phase space over long timescales of interest; this task is…

Machine Learning · Computer Science 2023-12-29 Ellis R. Crabtree , Juan M. Bello-Rivas , Ioannis G. Kevrekidis

Multivariate time series alignment is critical for ensuring coherent analysis across variables, but missing values and timestamp inconsistencies make this task highly challenging. Existing approaches often rely on prior imputation, which…

Databases · Computer Science 2025-12-23 Ding Jia , Jingyu Zhu , Yu Sun , Aoqian Zhang , Shaoxu Song , Haiwei Zhang , Xiaojie Yuan

We introduce a novel ensemble approach for feature selection based on hierarchical stacking for non-stationarity and/or a limited number of samples with a large number of features. Our approach exploits the co-dependency between features…

Machine Learning · Computer Science 2024-10-08 Aysin Tumay , Mustafa E. Aydin , Ali T. Koc , Suleyman S. Kozat