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Existing hemolysis algorithms are often constructed for laminar flows that expose red blood cells to a constant rate of shear. It remains an open question whether such models are applicable to turbulent flows, where there is a significant…

Fluid Dynamics · Physics 2023-12-18 Grant Rydquist , Mahdi Esmaily

We study segregation of a binary mixture of similarly charged particles under shear using particle-based simulations. We simulate particle dynamics using a discrete-element model including electrostatic interactions and find that particles…

Computational Physics · Physics 2017-05-12 R. Yoshimatsu , N. A. M. Araújo , T. Shinbrot , H. J. Herrmann

Blood exhibits a heterogeneous nature of hematocrit, velocity, and effective viscosity in microcapillaries. Microvascular bifurcations have a significant influence on the distribution of the blood cells and blood flow behavior. This paper…

Biological Physics · Physics 2016-02-24 Tong Wang , Uwitije Rongin , Zhongwen Xing

The flow behavior of blood in microvessels is directly associated with tissue perfusion and oxygen delivery. Current efforts on modeling blood flow have primarily focused on the flow properties of blood with red blood cells (RBCs) having a…

Soft Condensed Matter · Physics 2024-06-03 Wei Chien , Gerhard Gompper , Dmitry A. Fedosov

The study of vesicles under flow, a model system for red blood cells (RBCs), is an essential step in understanding various intricate dynamics exhibited by RBCs in vivo and in vitro. Quantitative 3D analyses of vesicles under flow are…

Soft Condensed Matter · Physics 2009-12-24 Thierry Biben , Alexander Farutin , Chaouqi Misbah

The geometry of blood vessels strongly affects hemostasis and thrombosis through red blood cell (RBC) dynamics and platelet margination. Growing platelet aggregates, in turn, reshape the local vessel wall topography, leading to a strongly…

Fluid Dynamics · Physics 2026-04-08 Eleonora Pero , Giovanna Tomaiuolo , Stefano Guido , Claire Denham , Timm Krueger

We introduce a novel approach to reveal ordering fluctuations in sheared dense suspensions, using line scanning in a combined rheometer and laser scanning confocal microscope. We validate the technique with a moderately dense suspension,…

Soft Condensed Matter · Physics 2022-11-04 Joia M. Miller , Daniel L. Blair , Jeffrey S. Urbach

The effect of oscillatory shear flows on turbulent transport of passive scalar fields is studied by numerical computations based on the results provided by E. Kim [\emph{Physics of Plasmas}, {\bf 13}, 022308, 2006]. Turbulent diffusion is…

Plasma Physics · Physics 2009-11-13 A. P. L. Newton , E. Kim

The deformability of human red blood cells (RBCs), which comprise almost 99% of the cells in whole blood, is largely related not only to pathophysiological blood flow but also to the levels of intracellular compounds. Therefore, statistical…

We investigate the shear thinning of red blood cell - dextran suspensions. Microscopic images show that at low polymer concentration, aggregation increases with increasing concentration until it reaches a maximum and then decreases again to…

Soft Condensed Matter · Physics 2015-10-13 Daniel Flormann , Katharina Schirra , Thomas Podgorski , Christian Wagner

We use a custom shear cell coupled to an optical microscope to investigate at the particle level the yielding transition in concentrated emulsions subjected to an oscillatory shear deformation. By performing experiments lasting thousands of…

Soft Condensed Matter · Physics 2014-08-27 E. D. Knowlton , D. J. Pine , L. Cipelletti

We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) for different volume fractions in a wall-bounded, effectively inertialess, small amplitude oscillatory shear (SAOS) flow for a wide range of applied…

Fluid Dynamics · Physics 2024-04-08 Naoki Takeishi , Marco Edoardo Rosti , Naoto Yokoyama , Luca Brandt

We study deformability-based sorting of same-size RBCs via DLD using an in-house integral equation solver. Our goal is to quantitatively characterize the physical mechanisms that enable the cell separation. To this end, we systematically…

Computational Physics · Physics 2018-11-30 Gokberk Kabacaoglu , George Biros

Red blood cells (RBCs) are the major component of blood and the flow of blood is dictated by that of RBCs. We employ vesicles, which consist of closed bilayer membranes enclosing a fluid, as a model system to study the behavior of RBCs…

Chaotic Dynamics · Physics 2015-06-22 Othmane Aouane , Marine Thiebaud , Abdelilah Benyoussef , Christian Wagner , Chaouqi Misbah

Measurements of wall shear-stress fluctuations on very long timescales ($\ge$ 1900 free-fall time units) are reported for turbulent Rayleigh-Benard (RB) convection in air at the heated bottom plate of a RB cell, 2.5 m in diameter and 2.5 m…

Fluid Dynamics · Physics 2019-01-23 Christoph Bruecker , Ronald Du Puits

We study a lattice model for the spreading of fluid films, which are a few molecular layers thick, in narrow channels with inert lateral walls. We focus on systems connected to two particle reservoirs at different chemical potentials,…

Statistical Mechanics · Physics 2009-11-13 C. Dotti , A. Gambassi , M. N. Popescu , S. Dietrich

The statistical properties of velocity gradients in a wall-bounded turbulent channel flow are discussed on the basis of three-dimensional direct numerical simulations. Our analysis is concentrated on the trend of the statistical properties…

Fluid Dynamics · Physics 2015-05-14 Thomas Boeck , Dmitry Krasnov , Joerg Schumacher

Due to their morphology, the dynamics of bacteria suspended in media can exhibit complex behaviors. In the presence of a shear, swimming bacteria experience a drift perpendicular to the shear plane. This drift, termed rheotaxis, is studied…

Red blood cells (RBCs) are an essential component of blood. A method to include the particulate nature of blood is introduced here with the goal of studying circulation in large-scale realistic vessels. The method uses a combination of the…

Medical Physics · Physics 2011-07-26 Simone Melchionna

We study a simple model of shear banding in which the flow-induced phase is destabilised by coupling between flow and microstructure (wormlike micellar length). By varying the strength of the instability and the applied shear rate, we find…

Soft Condensed Matter · Physics 2007-05-23 Suzanne Fielding , Peter Olmsted