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German text, english abstract: Mortality in gynecologic cancers, including cervical, ovarian, vaginal and vulvar cancers, is more than 6% internationally [1]. In many countries external radiotherapy is supplemented by brachytherapy with…

Medical Physics · Physics 2018-03-13 Andre Mastmeyer

In 2010, gynecologic malignancies were the 4th leading cause of death in U.S. women and for patients with extensive primary or recurrent disease, treatment with interstitial brachytherapy may be an option. However, brachytherapy requires…

Systems and Control · Computer Science 2014-04-25 Xiaojun Chen , Jan Egger

In this contribution, an image-guided therapy system supporting gynecologic radiation therapy is introduced. The overall workflow of the presented system starts with the arrival of the patient and ends with follow-up examinations by imaging…

Computational Engineering, Finance, and Science · Computer Science 2013-09-24 Jan Egger

A biopsy is the only diagnostic procedure for accurate histological confirmation of breast cancer. When sonographic placement is not feasible, a Magnetic Resonance Imaging(MRI)-guided biopsy is often preferred. The lack of real-time imaging…

Cervical cancer presents a significant global health challenge, necessitating advanced diagnostic and prognostic approaches for effective treatment. This paper investigates the potential of employing multi-modal medical imaging at various…

Medical Physics · Physics 2024-08-27 Haotian Feng , Emi Yoshida , Ke Sheng

Among all types of cancer, gynecological malignancies belong to the 4th most frequent type of cancer among women. Besides chemotherapy and external beam radiation, brachytherapy is the standard procedure for the treatment of these…

Computer Vision and Pattern Recognition · Computer Science 2016-08-24 Tobias Lüddemann , Jan Egger

Brachytherapy for localized prostate cancer consists in destroying cancer by introducing iodine radioactive seeds into the gland through hollow needles. The planning of the position of the seeds and their introduction into the prostate is…

Prostate brachytherapy involves implanting radioactive seeds (I125 for instance) permanently in the gland for the treatment of localized prostate cancers, e.g., cT1c-T2a N0 M0 with good prognostic factors. Treatment planning and seed…

In this work, we aim to predict the survival time (ST) of glioblastoma (GBM) patients undergoing different treatments based on preoperative magnetic resonance (MR) scans. The personalized and precise treatment planning can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Xiaofeng Liu , Nadya Shusharina , Helen A Shih , C. -C. Jay Kuo , Georges El Fakhri , Jonghye Woo

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

High dose rate brachytherapy (HDR-BT) is an appealing treatment option for superficial cancers that permits the delivery of higher local doses than other radiation modalities without a significant increase in toxicity. In order for HDR-BT…

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiration limits its accuracy. Recently, 3D imaging from a single X-ray projection has received extensive attention as a promising approach…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Miao Zhu , Qiming Fu , Bo Liu , Mengxi Zhang , Bojian Li , Xiaoyan Luo , Fugen Zhou

Brachytherapy involves bringing a radioactive source near tumor tissue using implanted needles. Image-guided brachytherapy planning requires amongst others, the reconstruction of the needles. Manually annotating these needles on patient…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Vangelis Kostoulas , Arthur Guijt , Ellen M. Kerkhof , Bradley R. Pieters , Peter A. N. Bosman , Tanja Alderliesten

Breast cancer remains the most commonly diagnosed malignancy among women in the developed world. Early detection through mammography screening plays a pivotal role in reducing mortality rates. While computer-aided diagnosis (CAD) systems…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Magnetic Resonance Imaging (MRI) is an important diagnostic tool for precise detection of various pathologies. Magnetic Resonance (MR) is more preferred than Computed Tomography (CT) due to the high resolution in MR images which help in…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Pranay Manocha , Snehal Bhasme , Tanvi Gupta , BK Panigrahi , Tapan K. Gandhi

Cervical cancer is one of the leading causes of death in women, and brachytherapy is currently the primary treatment method. However, it is important to precisely define the extent of paracervical tissue invasion to improve cancer diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Jjahao Zhang , Yin Gu , Deyu Sun , Yuhua Gao , Ming Gao , Ming Cui , Teng Zhang , He Ma

High dose-rate brachytherapy (HDRBT) is widely used for gynecological cancer treatment. Although commercial treatment planning systems (TPSs) have inverse optimization modules, it takes several iterations to adjust planning objectives to…

Medical Physics · Physics 2021-09-14 Huan Liu , Chang M Ma , Xun Jia , Chenyang Shen , Peter Klages , Kevin Albuquerque

The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-24 Spyridon Bakas , Mauricio Reyes , Andras Jakab , Stefan Bauer , Markus Rempfler , Alessandro Crimi , Russell Takeshi Shinohara , Christoph Berger , Sung Min Ha , Martin Rozycki , Marcel Prastawa , Esther Alberts , Jana Lipkova , John Freymann , Justin Kirby , Michel Bilello , Hassan Fathallah-Shaykh , Roland Wiest , Jan Kirschke , Benedikt Wiestler , Rivka Colen , Aikaterini Kotrotsou , Pamela Lamontagne , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Marc-Andre Weber , Abhishek Mahajan , Ujjwal Baid , Elizabeth Gerstner , Dongjin Kwon , Gagan Acharya , Manu Agarwal , Mahbubul Alam , Alberto Albiol , Antonio Albiol , Francisco J. Albiol , Varghese Alex , Nigel Allinson , Pedro H. A. Amorim , Abhijit Amrutkar , Ganesh Anand , Simon Andermatt , Tal Arbel , Pablo Arbelaez , Aaron Avery , Muneeza Azmat , Pranjal B. , W Bai , Subhashis Banerjee , Bill Barth , Thomas Batchelder , Kayhan Batmanghelich , Enzo Battistella , Andrew Beers , Mikhail Belyaev , Martin Bendszus , Eze Benson , Jose Bernal , Halandur Nagaraja Bharath , George Biros , Sotirios Bisdas , James Brown , Mariano Cabezas , Shilei Cao , Jorge M. Cardoso , Eric N Carver , Adrià Casamitjana , Laura Silvana Castillo , Marcel Catà , Philippe Cattin , Albert Cerigues , Vinicius S. Chagas , Siddhartha Chandra , Yi-Ju Chang , Shiyu Chang , Ken Chang , Joseph Chazalon , Shengcong Chen , Wei Chen , Jefferson W Chen , Zhaolin Chen , Kun Cheng , Ahana Roy Choudhury , Roger Chylla , Albert Clérigues , Steven Colleman , Ramiro German Rodriguez Colmeiro , Marc Combalia , Anthony Costa , Xiaomeng Cui , Zhenzhen Dai , Lutao Dai , Laura Alexandra Daza , Eric Deutsch , Changxing Ding , Chao Dong , Shidu Dong , Wojciech Dudzik , Zach Eaton-Rosen , Gary Egan , Guilherme Escudero , Théo Estienne , Richard Everson , Jonathan Fabrizio , Yong Fan , Longwei Fang , Xue Feng , Enzo Ferrante , Lucas Fidon , Martin Fischer , Andrew P. French , Naomi Fridman , Huan Fu , David Fuentes , Yaozong Gao , Evan Gates , David Gering , Amir Gholami , Willi Gierke , Ben Glocker , Mingming Gong , Sandra González-Villá , T. Grosges , Yuanfang Guan , Sheng Guo , Sudeep Gupta , Woo-Sup Han , Il Song Han , Konstantin Harmuth , Huiguang He , Aura Hernández-Sabaté , Evelyn Herrmann , Naveen Himthani , Winston Hsu , Cheyu Hsu , Xiaojun Hu , Xiaobin Hu , Yan Hu , Yifan Hu , Rui Hua , Teng-Yi Huang , Weilin Huang , Sabine Van Huffel , Quan Huo , Vivek HV , Khan M. Iftekharuddin , Fabian Isensee , Mobarakol Islam , Aaron S. Jackson , Sachin R. Jambawalikar , Andrew Jesson , Weijian Jian , Peter Jin , V Jeya Maria Jose , Alain Jungo , B Kainz , Konstantinos Kamnitsas , Po-Yu Kao , Ayush Karnawat , Thomas Kellermeier , Adel Kermi , Kurt Keutzer , Mohamed Tarek Khadir , Mahendra Khened , Philipp Kickingereder , Geena Kim , Nik King , Haley Knapp , Urspeter Knecht , Lisa Kohli , Deren Kong , Xiangmao Kong , Simon Koppers , Avinash Kori , Ganapathy Krishnamurthi , Egor Krivov , Piyush Kumar , Kaisar Kushibar , Dmitrii Lachinov , Tryphon Lambrou , Joon Lee , Chengen Lee , Yuehchou Lee , M Lee , Szidonia Lefkovits , Laszlo Lefkovits , James Levitt , Tengfei Li , Hongwei Li , Wenqi Li , Hongyang Li , Xiaochuan Li , Yuexiang Li , Heng Li , Zhenye Li , Xiaoyu Li , Zeju Li , XiaoGang Li , Wenqi Li , Zheng-Shen Lin , Fengming Lin , Pietro Lio , Chang Liu , Boqiang Liu , Xiang Liu , Mingyuan Liu , Ju Liu , Luyan Liu , Xavier Llado , Marc Moreno Lopez , Pablo Ribalta Lorenzo , Zhentai Lu , Lin Luo , Zhigang Luo , Jun Ma , Kai Ma , Thomas Mackie , Anant Madabushi , Issam Mahmoudi , Klaus H. Maier-Hein , Pradipta Maji , CP Mammen , Andreas Mang , B. S. Manjunath , Michal Marcinkiewicz , S McDonagh , Stephen McKenna , Richard McKinley , Miriam Mehl , Sachin Mehta , Raghav Mehta , Raphael Meier , Christoph Meinel , Dorit Merhof , Craig Meyer , Robert Miller , Sushmita Mitra , Aliasgar Moiyadi , David Molina-Garcia , Miguel A. B. Monteiro , Grzegorz Mrukwa , Andriy Myronenko , Jakub Nalepa , Thuyen Ngo , Dong Nie , Holly Ning , Chen Niu , Nicholas K Nuechterlein , Eric Oermann , Arlindo Oliveira , Diego D. C. Oliveira , Arnau Oliver , Alexander F. I. Osman , Yu-Nian Ou , Sebastien Ourselin , Nikos Paragios , Moo Sung Park , Brad Paschke , J. Gregory Pauloski , Kamlesh Pawar , Nick Pawlowski , Linmin Pei , Suting Peng , Silvio M. Pereira , Julian Perez-Beteta , Victor M. Perez-Garcia , Simon Pezold , Bao Pham , Ashish Phophalia , Gemma Piella , G. N. Pillai , Marie Piraud , Maxim Pisov , Anmol Popli , Michael P. Pound , Reza Pourreza , Prateek Prasanna , Vesna Prkovska , Tony P. Pridmore , Santi Puch , Élodie Puybareau , Buyue Qian , Xu Qiao , Martin Rajchl , Swapnil Rane , Michael Rebsamen , Hongliang Ren , Xuhua Ren , Karthik Revanuru , Mina Rezaei , Oliver Rippel , Luis Carlos Rivera , Charlotte Robert , Bruce Rosen , Daniel Rueckert , Mohammed Safwan , Mostafa Salem , Joaquim Salvi , Irina Sanchez , Irina Sánchez , Heitor M. Santos , Emmett Sartor , Dawid Schellingerhout , Klaudius Scheufele , Matthew R. Scott , Artur A. Scussel , Sara Sedlar , Juan Pablo Serrano-Rubio , N. Jon Shah , Nameetha Shah , Mazhar Shaikh , B. Uma Shankar , Zeina Shboul , Haipeng Shen , Dinggang Shen , Linlin Shen , Haocheng Shen , Varun Shenoy , Feng Shi , Hyung Eun Shin , Hai Shu , Diana Sima , M Sinclair , Orjan Smedby , James M. Snyder , Mohammadreza Soltaninejad , Guidong Song , Mehul Soni , Jean Stawiaski , Shashank Subramanian , Li Sun , Roger Sun , Jiawei Sun , Kay Sun , Yu Sun , Guoxia Sun , Shuang Sun , Yannick R Suter , Laszlo Szilagyi , Sanjay Talbar , Dacheng Tao , Dacheng Tao , Zhongzhao Teng , Siddhesh Thakur , Meenakshi H Thakur , Sameer Tharakan , Pallavi Tiwari , Guillaume Tochon , Tuan Tran , Yuhsiang M. Tsai , Kuan-Lun Tseng , Tran Anh Tuan , Vadim Turlapov , Nicholas Tustison , Maria Vakalopoulou , Sergi Valverde , Rami Vanguri , Evgeny Vasiliev , Jonathan Ventura , Luis Vera , Tom Vercauteren , C. A. Verrastro , Lasitha Vidyaratne , Veronica Vilaplana , Ajeet Vivekanandan , Guotai Wang , Qian Wang , Chiatse J. 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