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Mathematical modeling at the level of the full cardiovascular system requires the numerical approximation of solutions to a one-dimensional nonlinear hyperbolic system describing flow in a single vessel. This model is often simulated by…

Computational Physics · Physics 2015-04-22 Sebastian Acosta , Charles Puelz , Beatrice Riviere , Daniel J. Penny , Craig G. Rusin

Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…

Fluid Dynamics · Physics 2021-06-15 Giulia Bertaglia , Valerio Caleffi , Alessandro Valiani

We present well-balanced, high-order, semi-discrete numerical schemes for one-dimensional blood flow models with discontinuous mechanical properties and algebraic source terms representing friction and gravity. While discontinuities in…

Numerical Analysis · Mathematics 2025-08-29 Ernesto Pimentel-García , Lucas O. Müller , Carlos Parés

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

Quantitative Methods · Quantitative Biology 2025-08-27 Daehyun Kim , Jeffrey Tithof

In this paper, a multiscale constitutive framework for one-dimensional blood flow modeling is presented and discussed. By analyzing the asymptotic limits of the proposed model, it is shown that different types of blood propagation phenomena…

Numerical Analysis · Mathematics 2023-12-13 Giulia Bertaglia , Lorenzo Pareschi

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

The kinetic analyses of many-particle soft matter often employ many simulation studies of various physical phenomena which supplement the experimental limitations or compliment the theoretical findings of the study. Such simulations are…

Plasma Physics · Physics 2024-05-28 Allen Lobo , Vinod Kumar Sayal

In the last years, medical computer simulation has seen a great growth in several scientific branches, from modelling to numerical methods, going through computer science. The main goals of this incipient discipline are testing hypotheses…

Fluid Dynamics · Physics 2017-10-20 Cristóbal Rodero Gómez

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

We are interested in simulating blood flow in arteries with variable elasticity with a one dimensional model. We present a well-balanced finite volume scheme based on the recent developments in shallow water equations context. We thus get a…

Numerical Analysis · Mathematics 2012-04-10 Olivier Delestre , Pierre-Yves Lagrée

We consider a one-dimensional nonlocal hyperbolic model introduced to describe the formation and movement of self-organizing collectives of animals in homogeneous 1D environments. Previous research has shown that this model exhibits a large…

Numerical Analysis · Mathematics 2023-09-13 Thanh Trung Le , Raluca Eftimie

A noteworthy aspect in blood flow modeling is the definition of the mechanical interaction between the fluid flow and the biological structure that contains it, namely the vessel wall. It has been demonstrated that the addition of a viscous…

Fluid Dynamics · Physics 2022-06-14 Francesco Piccioli , Giulia Bertaglia , Alessandro Valiani , Valerio Caleffi

In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…

Tissues and Organs · Quantitative Biology 2022-10-10 Marvin Fritz , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth , Chengyue Wu

One-dimensional blood flow models take the general form of nonlinear hyperbolic systems but differ greatly in their formulation. One class of models considers the physically conserved quantities of mass and momentum, while another class…

Fluid Dynamics · Physics 2016-04-19 Charles Puelz , Suncica Canic , Beatrice Riviere , Craig G. Rusin

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Numerical simulation of viscoelastic flows is challenging because of the hyperbolic nature of viscoelastic constitutive equations. Despite their superior accuracy and efficiency, pseudo-spectral methods require the introduction of…

Fluid Dynamics · Physics 2020-10-20 Lu Zhu , Li Xi

We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…

We are interested in simulating blood flow in arteries with a one dimensional model. Thanks to recent developments in the analysis of hyperbolic system of conservation laws (in the Saint-Venant/ shallow water equations context) we will…

Numerical Analysis · Mathematics 2013-04-24 Olivier Delestre , Pierre-Yves Lagrée

Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…

We present a new model and a novel loosely coupled partitioned numerical scheme modeling fluid-structure interaction (FSI) in blood flow allowing non-zero longitudinal displacement. Arterial walls are modeled by a {linearly viscoelastic,…

Numerical Analysis · Mathematics 2015-06-05 Martina Bukac , Suncica Canic , Roland Glowinski , Josip Tambaca , Annalisa Quaini
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