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Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

Blood pressure monitoring is an essential component of hypertension management and in the prediction of associated comorbidities. Blood pressure is a dynamic vital sign with frequent changes throughout a given day. Capturing blood pressure…

Machine Learning · Computer Science 2020-07-29 Lida Zhang , Nathan C. Hurley , Bassem Ibrahim , Erica Spatz , Harlan M. Krumholz , Roozbeh Jafari , Bobak J. Mortazavi

Whole brain extraction, also known as skull stripping, is a process in neuroimaging in which non-brain tissue such as skull, eyeballs, skin, etc. are removed from neuroimages. Skull striping is a preliminary step in presurgical planning,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-05 Sara Ranjbar , Kyle W. Singleton , Lee Curtin , Cassandra R. Rickertsen , Lisa E. Paulson , Leland S. Hu , J. Ross Mitchell , Kristin R. Swanson

Developing an accurate and reliable injury predictor is central to the biomechanical studies of traumatic brain injury. State-of-the-art efforts continue to rely on empirical, scalar metrics based on kinematics or model-estimated tissue…

Quantitative Methods · Quantitative Biology 2018-05-28 Yunliang Cai , Shaoju Wu , Wei Zhao , Zhigang Li , Songbai Ji

Twenty cases of different brain pathology have been studied via MRI using an open resistive magnet with magnetic field strength of 0.2 Tesla. The relative signal intensity with respect to the repetition time (TR) at fixed echo time (TE)…

Medical Physics · Physics 2009-12-05 Indra Dev Sahu , Sheshkant Aryal , Shanta Lal Shrestha , Ram Kumar Ghimire

Objective: Traumatic brain injuries and damage are major causes of death and disability. We propose a 3D fully coupled electro-mechanical model of a nerve bundle to investigate the electrophysiological impairments due to trauma at the…

Biological Physics · Physics 2020-09-02 Ilaria Cinelli , Michel Destrade , Maeve Duffy , Peter McHugh

The paper presents a study of an inter-stimulus interval (ISI) influence on a tactile point-pressure stimulus-based brain-computer interface's (tpBCI) classification accuracy. A novel tactile pressure generating tpBCI stimulator is also…

Neurons and Cognition · Quantitative Biology 2016-11-17 Kensuke Shimizu , Shoji Makino , Tomasz M. Rutkowski

Vibration injury in the hand-arm system from hand-held machines is one of the most common occupational health injuries and causes severe and often chronic nerve and vascular injury to the operator. Machines emitting shock vibrations, e.g.,…

Signal Processing · Electrical Eng. & Systems 2022-11-17 Pontus Johannisson , Hans Lindell

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Depression is the most common psychological disorder and is considered as a leading cause of disability and suicide worldwide. An automated system capable of detecting signs of depression in human speech can contribute to ensuring timely…

Sound · Computer Science 2023-02-21 Mashrura Tasnim , Jekaterina Novikova

Flexible strain sensors are critical to several potential intelligent applications, such as human-machine interfaces, soft robotics, human motion detection, and safety monitoring of components. Stretchable functional materials are important…

Mild traumatic brain injury (mTBI) is a complex syndrome that affects up to 600 per 100,000 individuals, with a particular concentration among military personnel. About half of all mTBI patients experience a diverse array of chronic…

Despite rapid progress in building conversational AI agents, robustness is still largely untested. Small shifts in user behavior, such as being more impatient, incoherent, or skeptical, can cause sharp drops in agent performance, revealing…

Artificial Intelligence · Computer Science 2026-03-18 Muyu He , Anand Kumar , Tsach Mackey , Meghana Rajeev , James Zou , Nazneen Rajani

Human-Computer Interaction (HCI) is a multi-modal, interdisciplinary field focused on designing, studying, and improving the interactions between people and computer systems. This involves the design of systems that can recognize,…

Human-Computer Interaction · Computer Science 2025-08-15 Paul Schreiber , Beyza Cinar , Lennart Mackert , Maria Maleshkova

Short inversion time inversion recovery (STIR) MRI is widely used in clinical practice to identify and quantify inflammation in axial spondyloarthritis. However, assessment of STIR images is limited by the need for qualitative evaluation,…

Joint modeling of diffusion and relaxation has seen growing interest due to its potential to provide complementary information about tissue microstructure. For brain white matter, we designed an optimal diffusion-relaxometry MRI protocol…

Brain injuries are a major reason for mortality and morbidity following trauma in sports, work and traffic. Apart from the trauma at the site of impact (coup injury), other regions of the brain remote from the impact locations (non-coup)…

Quantitative Methods · Quantitative Biology 2020-12-02 Rajesh Kumar , Md Zubair , Sudipto Mukherjee , Jacobo Antona Makoshi

The heterogeneous micromechanical properties of biological tissues have profound implications across diverse medical and engineering domains. However, identifying full-field heterogeneous elastic properties of soft materials using…

Numerical Analysis · Mathematics 2025-07-09 Wensi Wu , Mitchell Daneker , Kevin T. Turner , Matthew A. Jolley , Lu Lu

Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hyper-elastic strain modelling of brain atrophy, during healthy…

Neurons and Cognition · Quantitative Biology 2021-08-19 Mariana Da Silva , Carole H. Sudre , Kara Garcia , Cher Bass , M. Jorge Cardoso , Emma C. Robinson

A large scale computational model of the basal ganglia (BG) network is proposed to describes movement disorder including deep brain stimulation (DBS). The model of this complex network considers four areas of the basal ganglia network: the…

Neurons and Cognition · Quantitative Biology 2021-03-15 Konstantinos Spiliotis , Jens Starke , Denise Franz , Angelika Richter , Rüdiger Köhling