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Important insights towards the explainability of neural networks reside in the characteristics of their decision boundaries. In this work, we borrow tools from the field of adversarial robustness, and propose a new perspective that relates…

Machine Learning · Computer Science 2020-10-16 Guillermo Ortiz-Jimenez , Apostolos Modas , Seyed-Mohsen Moosavi-Dezfooli , Pascal Frossard

The determination and classification of fixed points of large Boolean networks is addressed in terms of constraint satisfaction problem. We develop a general simplification scheme that, removing all those variables and functions belonging…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Correale , M. Leone , A. Pagnani , M. Weigt , R. Zecchina

We consider the following question on the relationship between the asymptotic behaviours of asynchronous dynamics of Boolean networks and their regulatory structures: does the presence of a cyclic attractor imply the existence of a local…

Discrete Mathematics · Computer Science 2018-10-23 Elisa Tonello , Etienne Farcot , Claudine Chaouiya

Identification of attractors, that is, stable states and sustained oscillations, is an important step in the analysis of Boolean models and exploration of potential variants. We describe an approach to the search for asynchronous cyclic…

Discrete Mathematics · Computer Science 2024-03-29 Elisa Tonello , Loïc Paulevé

We study Boolean networks which are simple spatial models of the highly conserved Delta-Notch system. The models assume the inhibition of Delta in each cell by Notch in the same cell, and the activation of Notch in presence of Delta in…

Discrete Mathematics · Computer Science 2020-07-31 Elisa Tonello , Heike Siebert

Given a Boolean network BN and a subset A of attractors of BN, we study the problem of identifying a minimal subset C of vertices of BN, such that the dynamics of BN can reach from a state s in any attractor As in A to any attractor At in A…

Systems and Control · Computer Science 2018-06-29 Soumya Paul , Jun Pang , Cui Su

This paper studies the mathematical properties of collectively canalizing Boolean functions, a class of functions that has arisen from applications in systems biology. Boolean networks are an increasingly popular modeling framework for…

Discrete Mathematics · Computer Science 2023-06-07 Claus Kadelka , Benjamin Keilty , Reinhard Laubenbacher

This paper addresses the problem of finding cycles in the state transition graphs of synchronous Boolean networks. Synchronous Boolean networks are a class of deterministic finite state machines which are used for the modeling of gene…

Molecular Networks · Quantitative Biology 2009-01-29 Elena Dubrova , Maxim Teslenko

Chaotic functions are characterized by sensitivity to initial conditions, transitivity, and regularity. Providing new functions with such properties is a real challenge. This work shows that one can associate with any Boolean network a…

Discrete Mathematics · Computer Science 2011-12-08 J. M. Bahi , J. -F. Couchot , C. Guyeux , A. Richard

A key ingredient of current models proposed to capture the topological evolution of complex networks is the hypothesis that highly connected nodes increase their connectivity faster than their less connected peers, a phenomenon called…

Statistical Mechanics · Physics 2009-11-07 H. Jeong , Z. Neda , A. -L. Barabasi

A Boolean network (BN) with $n$ components is a discrete dynamical system described by the successive iterations of a function $f:\{0,1\}^n \to \{0,1\}^n$. This model finds applications in biology, where fixed points play a central role.…

Combinatorics · Mathematics 2022-02-10 Florian Bridoux , Amélia Durbec , Kévin Perrot , Adrien Richard

We study the intrinsic properties of attractors in the Boolean dynamics in complex network with scale-free topology, comparing with those of the so-called random Kauffman networks. We have numerically investigated the frozen and relevant…

Disordered Systems and Neural Networks · Physics 2007-08-21 Shu-ichi Kinoshita , Kazumoto Iguchi , Hiroaki S. Yamada

The Ott-Antonsen (OA) ansatz [Chaos 18, 037113 (2008), Chaos 19, 023117 (2009)] has been widely used to describe large systems of coupled phase oscillators. If the coupling is sinusoidal and if the phase dynamics does not depend on the…

Chaotic Dynamics · Physics 2023-04-20 Bastian Pietras , Andreas Daffertshofer

Logical models have been successfully used to describe regulatory and signaling networks without requiring quantitative data. However, existing data is insufficient to adequately define a unique model, rendering the parametrization of a…

Discrete Mathematics · Computer Science 2019-01-24 José E. R. Cury , Pedro T. Monteiro , Claudine Chaouiya

Boolean networks (BNs) are important models for gene regulatory networks and many other biological systems. In this paper, we study the minimal controllability problem of threshold and XOR BNs with degree constraints. Firstly, we derive…

Systems and Control · Electrical Eng. & Systems 2025-09-22 Christopher H. Fok , Liangjie Sun , Tatsuya Akutsu , Wai-Ki Ching

This study investigates the suitability of the annealed approximation in high-dimensional systems characterized by dense networks with quenched link disorder, employing models of coupled oscillators. We demonstrate that dynamic equations…

Statistical Mechanics · Physics 2024-03-25 Jaegon Um , Hyunsuk Hong , Hyunggyu Park

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

Artificial neurons with arbitrarily complex internal structure are introduced. The neurons can be described in terms of a set of internal variables, a set activation functions which describe the time evolution of these variables and a set…

Neural and Evolutionary Computing · Computer Science 2007-05-23 G. A. Kohring

We describe systems using Kauffman and similar networks. They are directed funct ioning networks consisting of finite number of nodes with finite number of discr ete states evaluated in synchronous mode of discrete time. In this paper we…

Disordered Systems and Neural Networks · Physics 2009-11-13 Andrzej Gecow

Gene regulatory networks can be successfully modeled as Boolean networks. A much discussed hypothesis says that such model networks reproduce empirical findings the best if they are tuned to operate at criticality, i.e. at the borderline…

Molecular Networks · Quantitative Biology 2016-10-12 Pablo Villegas , José Ruiz-Franco , Jorge Hidalgo , Miguel A. Muñoz
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