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Boolean networks are a valuable class of discrete dynamical systems models, but they remain fundamentally limited by their inability to capture multi-way interactions in their components. To remedy this limitation, we propose a model of…

Dynamical Systems · Mathematics 2024-09-02 Kevin M. Stoltz , Cliff A. Joslyn

In this paper, we propose an approach for modeling and analysis of a number of phenomena of collective behavior. By collectives we mean multi-agent systems that transition from one state to another at discrete moments of time. The behavior…

Social and Information Networks · Computer Science 2015-06-23 Stepan Kochemazov , Alexander Semenov

To simplify the analysis of Boolean networks, a reduction in the number of components is often considered. A popular reduction method consists in eliminating components that are not autoregulated, using variable substitution. In this work,…

Discrete Mathematics · Computer Science 2024-03-27 Robert Schwieger , Elisa Tonello

Boolean networks constitute relevant mathematical models to study the behaviours of genetic and signalling networks. These networks define regulatory influences between molecular nodes, each being associated to a Boolean variable and a…

Discrete Mathematics · Computer Science 2025-06-24 José E. R. Cury , Patrícia Tenera Roxo , Vasco Manquinho , Claudine Chaouiya , Pedro T. Monteiro

A model of Boolean agents competing in a market is presented where each agent bases his action on information obtained from a small group of other agents. The agents play a competitive game that rewards those in the minority. After a long…

Statistical Mechanics · Physics 2009-10-31 Maya Paczuski , Kevin E. Bassler , Alvaro Corral

This paper is concerned with the reduction of a noisy synchronous Boolean network to a coarse-grained Markov chain with number of states being equal to the number of attractors of the original network.

Biological Physics · Physics 2009-12-21 F. Fourré , D. Baurain

Effective control of biological systems can often be achieved through the control of a surprisingly small number of distinct variables. We bring clarity to such results using the formalism of Boolean dynamical networks, analyzing the…

Molecular Networks · Quantitative Biology 2021-09-13 Enrico Borriello , Bryan C. Daniels

Boolean automata networks (aka Boolean networks) are space-time discrete dynamical systems, studied as a model of computation and as a representative model of natural phenomena. A collection of simple entities (the automata) update their…

Discrete Mathematics · Computer Science 2024-02-12 Kévin Perrot , Sylvain Sené , Léah Tapin

Logical models have been successfully used to describe regulatory and signaling networks without requiring quantitative data. However, existing data is insufficient to adequately define a unique model, rendering the parametrization of a…

Discrete Mathematics · Computer Science 2019-01-24 José E. R. Cury , Pedro T. Monteiro , Claudine Chaouiya

Random Boolean networks (RBNs) have been a popular model of genetic regulatory networks for more than four decades. However, most RBN studies have been made with random topologies, while real regulatory networks have been found to be…

Cellular Automata and Lattice Gases · Physics 2015-03-17 Rodrigo Poblanno-Balp , Carlos Gershenson

Boolean networks, inspired by gene regulatory networks, were developed to understand the complex behaviors observed in biological systems, with network attractors corresponding to biological phenotypes or cell types. In this article, we…

Molecular Networks · Quantitative Biology 2025-11-25 Venkata Sai Narayana Bavisetty , Matthew Wheeler , Reinhard Laubenbacher , Claus Kadelka

Boolean networks are dynamical models of disease development in which the activation levels of genes are represented by binary variables. Given a Boolean network, controls represent mutations or medical treatments that fix the activation…

Optimization and Control · Mathematics 2026-04-02 Kyungduk Moon , Kangbok Lee , Loïc Paulevé

A conjunctive Boolean network (CBN) is a finite state dynamical system, whose variables take values from a binary set, and the value update rule for each variable is a Boolean function consisting only of logic AND operations. We investigate…

Dynamical Systems · Mathematics 2019-07-11 Xudong Chen , Zuguang Gao , Tamer Başar

We consider the following question on the relationship between the asymptotic behaviours of asynchronous dynamics of Boolean networks and their regulatory structures: does the presence of a cyclic attractor imply the existence of a local…

Discrete Mathematics · Computer Science 2018-10-23 Elisa Tonello , Etienne Farcot , Claudine Chaouiya

The problem of reliability of the dynamics in biological regulatory networks is studied in the framework of a generalized Boolean network model with continuous timing and noise. Using well-known artificial genetic networks such as the…

Molecular Networks · Quantitative Biology 2008-05-28 Stefan Braunewell , Stefan Bornholdt

Dynamical systems theory and complexity science provide powerful tools for analysing artificial agents and robots. Furthermore, they have been recently proposed also as a source of design principles and guidelines. Boolean networks are a…

Artificial Intelligence · Computer Science 2015-03-18 Andrea Roli , Mattia Manfroni , Carlo Pinciroli , Mauro Birattari

We evaluate the probability that a Boolean network returns to an attractor after perturbing h nodes. We find that the return probability as function of h can display a variety of different behaviours, which yields insights into the…

Statistical Mechanics · Physics 2010-07-02 C. Fretter , B. Drossel

In this paper we consider a network of boolean agents that compete for a limited resource. The agents play the so called Generalized Minority Game where the capacity level is allowed to vary externally. We study the properties of such a…

Adaptation and Self-Organizing Systems · Physics 2009-11-10 Aram Galstyan , Kristina Lerman

We present a computational method for finding attractors (ergodic sets of states) of Boolean networks under asynchronous update. The approach is based on a systematic removal of state transitions to render the state transition graph…

Disordered Systems and Neural Networks · Physics 2010-08-24 Thomas Skodawessely , Konstantin Klemm

Biological systems operate under persistent noise, which can alter system states and induce transitions between attractors. Here, we study the attractor dynamics of Boolean networks focusing on the transitions between attractors induced by…

Molecular Networks · Quantitative Biology 2026-03-05 Byungjoon Min , Jeehye Choi , Reinhard Laubenbacher