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We present a new method for high-resolution nanoscale magnetic resonance imaging (nano-MRI) that combines the high spin sensitivity of nanowire-based magnetic resonance detection with high spectral resolution nuclear magnetic resonance…

Mesoscale and Nanoscale Physics · Physics 2018-03-07 William Rose , Holger Haas , Angela Q. Chen , Nari Jeon , Lincoln J. Lauhon , David G. Cory , Raffi Budakian

We report the use of a silicon nanowire mechanical oscillator as a low-temperature nuclear magnetic resonance force sensor to detect the statistical polarization of 1H spins in polystyrene. Under operating conditions, the nanowire…

Other Condensed Matter · Physics 2015-05-30 John M. Nichol , Eric R. Hemesath , Lincoln J. Lauhon , Raffi Budakian

Optically-detected magnetic resonance using Nitrogen Vacancy (NV) color centres in diamond is a leading modality for nanoscale magnetic field imaging, as it provides single electron spin sensitivity, three-dimensional resolution better than…

Mesoscale and Nanoscale Physics · Physics 2015-10-28 K. Arai , C. Belthangady , H. Zhang , N. Bar-Gill , S. J. DeVience , P. Cappellaro , A. Yacoby , R. L. Walsworth

When probing nuclear spins in materials on the nanometer scale, random fluctuations of the spin polarization will exceed the mean Boltzmann polarization for sample volumes below about (100nm)^3. In this work, we use magnetic resonance force…

Mesoscale and Nanoscale Physics · Physics 2008-01-14 C. L. Degen , M. Poggio , H. J. Mamin , D. Rugar

Soon after the first measurements of nuclear magnetic resonance (NMR) in a condensed matter system, Bloch predicted the presence of statistical fluctuations proportional to $1/\sqrt{N}$ in the polarization of an ensemble of $N$ spins. First…

Mesoscale and Nanoscale Physics · Physics 2013-10-07 P. Peddibhotla , F. Xue , H. I. T. Hauge , S. Assali , E. P. A. M. Bakkers , M. Poggio

Dynamic nuclear polarization (DNP) has revolutionized the field of NMR spectroscopy, expanding its reach and capabilities to investigate diverse materials, biomolecules, and complex dynamic processes. Bringing high-efficiency DNP to the…

Mesoscale and Nanoscale Physics · Physics 2024-02-27 Sahand Tabatabaei , Pritam Priyadarsi , Namanish Singh , Pardis Sahafi , Daniel Tay , Andrew Jordan , Raffi Budakian

We report a method for accelerated nanoscale nuclear magnetic resonance imaging by detecting several signals in parallel. Our technique relies on phase multiplexing, where the signals from different nuclear spin ensembles are encoded in the…

Mesoscale and Nanoscale Physics · Physics 2015-08-11 B. A. Moores , A. Eichler , Y. Tao , H. Takahashi , P. Navaretti , C. L. Degen

Magnetic spin resonance is a key non-invasive sensing and imaging technique across the life-, material- and fundamental sciences with further medical and commercial applications. Recent advances using paramagnetic color centers enable…

Mesoscale and Nanoscale Physics · Physics 2018-07-24 Florestan Ziem , Marwa Garsi , Helmut Fedder , Jörg Wrachtrup

Achieving atomic resolution is the ultimate limit of magnetic resonance imaging (MRI), and attaining this capability offers enormous technological and scientific opportunities, from drug development to understanding the dynamics in…

Magnetic Resonance Imaging (MRI) can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due…

Mesoscale and Nanoscale Physics · Physics 2010-11-03 C. A. Meriles , L. Jiang , G. Goldstein , J. S. Hodges , J. R. Maze , M. D. Lukin , P. Cappellaro

Nanoscale magnetic resonance imaging (nanoMRI) aims at obtaining structure at the single molecule level. Most of the techniques for effecting a nanoMRI gradient use small permanent magnets. Here, we present a switchable magnetic field…

Mesoscale and Nanoscale Physics · Physics 2025-03-12 Leora Schein-Lubomirsky , Yarden Mazor , Rainer Stöhr , Andrej Denisenko , Amit Finkler

Nuclear magnetic resonance (NMR) imaging with nanometer resolution requires new detection techniques with sensitivity well beyond the capability of conventional inductive detection. Here, we demonstrate two dimensional imaging of $^1$H NMR…

Mesoscale and Nanoscale Physics · Physics 2015-06-19 D. Rugar , H. J. Mamin , M. H. Sherwood , M. Kim , C. T. Rettner , K. Ohno , D. D. Awschalom

Magnetic resonance imaging, based on the manipulation and detection of nuclear spins, is a powerful imaging technique that typically operates on the scale of millimeters to microns. Using magnetic resonance force microscopy, we have…

Other Condensed Matter · Physics 2007-06-27 H. J. Mamin , M. Poggio , C. L. Degen , D. Rugar

We measure the statistical polarization of quadrupolar nuclear spins in a sub-micrometer (0.6 um^3) particle of GaAs using magnetic resonance force microscopy. The crystalline sample is cut out of a GaAs wafer and attached to a…

Mesoscale and Nanoscale Physics · Physics 2016-11-25 Fei Xue , D. P. Weber , P. Peddibhotla , M. Poggio

Two-dimensional Nuclear Magnetic Resonance (NMR) is essential in molecular structure determination. The Nitrogen-Vacancy (NV) center in diamond has been proposed and developed as an outstanding quantum sensor to realize NMR in nanoscale. In…

The implementation of nuclear magnetic resonance (NMR) at the nanoscale is a major challenge, as conventional systems require relatively large ensembles of spins and limit resolution to mesoscopic scales. New approaches based on quantum…

Optically active spin defects in solids offer promising platforms to investigate nuclear spin clusters with high sensitivity and atomic-site resolution. To leverage near-surface defects for molecular structure analysis in chemical and…

Nuclear magnetic resonance spectroscopy with solid-state spin sensors is a promising pathway for the detection of nuclear spins at the micro- and nanoscale. Although many nanoscale experiments rely on a single sensor spin for the detection…

Mechanical resonators operating in the high-frequency regime have become a versatile platform for fundamental and applied quantum research. Their exceptional properties, such as low mass and high quality factor, make them also very…

Mesoscale and Nanoscale Physics · Physics 2023-11-29 Diego A. Visani , Letizia Catalini , Christian L. Degen , Alexander Eichler , Javier del Pino

Nuclear magnetic resonance (NMR) spectroscopy provides unparalleled access to molecular structure and dynamics but is traditionally limited by weak signal strength, requiring large sample volumes and high magnetic fields. Here, we…

Applied Physics · Physics 2026-04-29 Dileep Singh , Riley W. Hooper , Christoph Findler , Utsab Banerjee , Dominik B. Bucher
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