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We study the interaction of lipid bilayers with short chain alcohols using molecular dynamics on different length scales. We use detailed atomistic modeling and modeling on the length scale where an alcohol is just an amphiphilic dimer. Our…

Biological Physics · Physics 2015-06-26 Allison N. Dickey , Roland Faller

Using integral equation theory of liquids to a binary mixed fluid lipid membrane, we study the membrane-mediated interactions between the macroions and the redistribution of neutral and charged lipids due to binding macroions. We find that…

Soft Condensed Matter · Physics 2015-06-25 Xia-qing Shi , Yu-qiang Ma

We investigate the properties of membranes under tension by Monte-Carlo simulations of a generic coarse-grained model for lipid bilayers. We give a comprising overview of the behavior of several membrane characteristics, such as the area…

Biological Physics · Physics 2010-03-17 Jörg Neder , Beate West , Peter Nielaba , Friederike Schmid

We study a continuum model of the lipid bilayer based on minimizing the free energy of a mixture of water and lipid molecules. This paper extends previous work by Blom & Peletier (2004) in the following ways. (a) It formulates a more…

Soft Condensed Matter · Physics 2020-06-05 Phillip L. Wilson , Huaxiong Huang , Shu Takagi

It is well known that lipid membranes respond to a threshold transmembrane electric field through a reversible mechanism called electroporation, where hydrophilic water pores form across the membrane, an effect widely used in biological…

Soft Condensed Matter · Physics 2023-04-17 Di Jin , Yu Zhang , Jacob Klein

Biological membranes are complex, dynamic structures essential for cellular compartmentalization, signaling, and mechanical integrity. The molecular organization of eukaryotic membranes has been extensively studied, including the lipid…

Soft Condensed Matter · Physics 2025-08-05 Nicolo Tormena , Teuta Pilizota , Kislon Voïtchovsky

Using fluorescence microscopy we study the adsorption of single latex microparticles at a water/water interface between demixing aqueous solutions of polymers, generally known as a water-in-water emulsion. Similar microparticles at the…

Soft Condensed Matter · Physics 2018-05-23 Louis Keal , Carlos E. Colosqui , Hans Tromp , Cecile Monteux

Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding environment. When the membrane relaxes from a structural perturbation, the dynamics of…

Soft Condensed Matter · Physics 2015-07-27 R. J. Bingham , S. W. Smye , P. D. Olmsted

A variety of models for the membrane-mediated interaction of particles in lipid membranes, mostly well-established in theoretical physics, is reviewed from a mathematical perspective. We provide mathematically consistent formulations in a…

Analysis of PDEs · Mathematics 2016-06-29 Charles M. Elliott , Carsten Gräser , Graham Hobbs , Ralf Kornhuber , Maren-Wanda Wolf

We use a simple and efficient computer model to investigate the physical properties of bilayer membranes. The amphiphilic molecules are modeled as short rigid trimers with finite range pair interactions between them. The pair potentials…

Soft Condensed Matter · Physics 2009-11-10 Oded Farago

Lipid membranes, the barrier defining living cells and many of their sub-compartments, bind to a wide variety of nano- and micro-meter sized objects. In the presence of strong adhesive forces, membranes can strongly deform and wrap the…

Particles embedded in a fluctuating interface experience forces and torques mediated by the deformations and by the thermal fluctuations of the medium. Considering a system of two cylinders bound to a fluid membrane we show that the…

Soft Condensed Matter · Physics 2011-05-31 Pierre Gosselin , Hervé Mohrbach , Martin Michael Müller

Tension in lipid membranes is often controlled externally, by pulling on the boundary of the membrane or changing osmotic pressure across a curved membrane. But modifications of the tension can also be induced in an internal fashion, for…

Soft Condensed Matter · Physics 2015-05-20 Michael A. Lomholt , Bastien Loubet , John H. Ipsen

A phenomenological Landau elasticity for the shape, dilation, and lipid-tilt of bilayer membranes is developed. The shape mode couples with the sum of the monolayers' tilt, while the dilation mode couples with the difference of the…

Soft Condensed Matter · Physics 2009-10-31 J. -B. Fournier

Many cell functions require a concerted effort from multiple membrane proteins, for example, for signaling, cell division, and endocytosis. One contribution to their successful self-organization stems from the membrane deformations that…

Soft Condensed Matter · Physics 2023-06-21 Ali Azadbakht , Billie Meadowcroft , Juraj Májek , Anđela Šarić , Daniela J. Kraft

We investigate effective interactions between a colloidal particle, immersed in a binary mixture of smaller spheres, and a semipermeable membrane. The colloid is modeled as a big hard sphere and the membrane is represented as an infinitely…

Soft Condensed Matter · Physics 2007-05-23 Pawel Bryk

Coulomb drag experiments in which the inter-layer resistivity is measured are important as they provide information on the Coulomb interactions in bilayer systems. When the layer densities are low correlation effects become significant to…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 R. Asgari , B. Tanatar , B. Davoudi

We derived free energy functional of a bilayer lipid membrane from the first principles of elasticity theory. The model explicitly includes position-dependent mutual slide of monolayers and bending deformation. Our free energy functional of…

Soft Condensed Matter · Physics 2009-11-10 S. V. Baoukina , S. I. Mukhin

We consider how membrane fluctuations can modify the miscibility of lipid mixtures, that is to say how the phase diagram of a boundary-constrained membrane is modified when the membrane is allowed to fluctuate freely in the case of zero…

Soft Condensed Matter · Physics 2015-06-11 David S. Dean , V. Adrian Parsegian , R. Podgornik

We use computer simulations and a simple free energy model to study the response of a bilayer membrane to the application of a negative (compressive) mechanical tension. Such a tension destabilizes the long wavelength undulation modes of…

Soft Condensed Matter · Physics 2015-06-24 Yotam Y. Avital , Oded Farago