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Effective multicellularity requires both cooperation and competition between constituent cells. Cooperation involves sacrificing individual fitness in favor of that of the community, but excessive cooperation makes the community susceptible…

Populations and Evolution · Quantitative Biology 2022-11-21 Thomas C. T. Michaels , L. Mahadevan

Life is a complex biological phenomenon represented by numerous chemical, physical and biological processes performed by a biothermodynamic system/cell/organism. Both living organisms and inanimate objects are subject to aging, a biological…

Other Quantitative Biology · Quantitative Biology 2018-01-25 Marko Popovic

The capacity to adapt can greatly influence the success of systems that need to compensate for damaged parts, learn how to achieve robust performance in new environments, or exploit novel opportunities that originate from new technological…

Adaptation and Self-Organizing Systems · Physics 2011-12-15 James Whitacre , Axel Bender

We suggest to simulate evolution of complex organisms constrained by the sole requirement of robustness in their expression patterns. This scenario is illustrated by evolving discrete logical networks with epigenetic properties. Evidence…

Statistical Mechanics · Physics 2007-05-23 Stefan Bornholdt , Kim Sneppen

The behavior of ecological systems mainly relies on the interactions between the species it involves. We consider the problem of inferring the species interaction network from abundance data. To be relevant, any network inference…

Applications · Statistics 2019-10-29 Raphaëlle Momal , Stéphane Robin , Christophe Ambroise

Large sets of genotypes give rise to the same phenotype because phenotypic expression is highly redundant. Accordingly, a population can accept mutations without altering its phenotype, as long as thegenotype mutates into another one on the…

Populations and Evolution · Quantitative Biology 2015-02-18 Susanna Manrubia , José A. Cuesta

Complex networks are ubiquitous: a cell, the human brain, a group of people and the Internet are all examples of interconnected many-body systems characterized by macroscopic properties that cannot be trivially deduced from those of their…

Human diseases spread over networks of contacts between individuals and a substantial body of recent research has focused on the dynamics of the spreading process. Here we examine a model of two competing diseases spreading over the same…

Physics and Society · Physics 2015-03-19 Brian Karrer , M. E. J. Newman

Complex systems, in many different scientific sectors, show coarse-grain properties with simple growth laws with respect to fundamental microscopic algorithms. We propose a classification scheme of growth laws which includes human aging,…

Biological Physics · Physics 2012-07-17 P. Castorina , P. Blanchard

Aging, understood as the tendency to remain in a given state the longer the persistence time in that state, plays a crucial role in the dynamics of complex systems. In this paper, we explore the influence of aging on coevolution models,…

Physics and Society · Physics 2025-10-27 Byungjoon Min , Maxi San Miguel

The presence of burstiness in temporal social networks, revealed by a power law form of the waiting time distribution of consecutive interactions, is expected to produce aging effects in the corresponding time-integrated network. Here we…

Physics and Society · Physics 2015-04-24 Antoine Moinet , Michele Starnini , Romualdo Pastor-Satorras

The adaptive and innate branches of the vertebrate immune system work in close collaboration to protect organisms from harmful pathogens. As an organism ages its immune system undergoes immunosenescence, characterized by declined…

Tissues and Organs · Quantitative Biology 2020-08-28 Eric W. Jones , Jiming Sheng , Jean M. Carlson , Shenshen Wang

Mutualistic interactions, which are beneficial for both interacting species, are recurrently present in ecosystems. Observations of natural systems showed that, if we draw mutualistic relationships as binary links between species, the…

Physics and Society · Physics 2019-08-21 Clàudia Payrató Borrás , Laura Hernández , Yamir Moreno

Many complex systems--from social and communication networks to biological networks and the Internet--are thought to exhibit scale-free structure. However, prevailing explanations rely on the constant addition of new nodes, an assumption…

Adaptation and Self-Organizing Systems · Physics 2022-11-10 Christopher W. Lynn , Caroline M. Holmes , Stephanie E. Palmer

We represent a process of learning by using bit strings, where 1-bits represent the knowledge acquired by individuals. Two ways of learning are considered: individual learning by trial-and-error; and social learning by copying knowledge…

Populations and Evolution · Quantitative Biology 2007-05-23 Armando Ticona Bustillos , Paulo Murilo C. de Oliveira

Subgraphs and cycles are often used to characterize the local properties of complex networks. Here we show that the subgraph structure of real networks is highly time dependent: as the network grows, the density of some subgraphs remains…

Disordered Systems and Neural Networks · Physics 2009-11-11 Alexei Vazquez , Joao G. Oliveira , Albert-Laszlo Barabasi

Local perturbations of individual metabolic reactions may result in different levels of lethality, depending on their roles in metabolism and the size of subsequent cascades induced by their failure. Moreover, essentiality of individual…

Molecular Networks · Quantitative Biology 2019-03-27 P. Kim , K. Han , D. -S. Lee , B. Kahng

We study the evolution of networks when the creation and decay of links are based on the position of nodes in the network measured by their centrality. We show that the same network dynamics arises under various centrality measures, and…

Physics and Society · Physics 2013-05-29 Michael D. Koenig , Claudio J. Tessone

In a complex network, different groups of nodes may have existed for different amounts of time. To detect the evolutionary history of a network is of great importance. We present a general method based on spectral analysis to address this…

Physics and Society · Physics 2012-02-21 Zhu Guimei , Yang Huijie , Yang Rui , Ren Jie , Li Baowen , Lai Ying-Cheng

How multicellular life forms evolved out from unicellular ones constitutes a major problem in our understanding of the evolution of our biosphere. A recent set of experiments involving yeast cell populations has shown that selection for…

Populations and Evolution · Quantitative Biology 2015-11-10 Salva Duran-Nebreda , Ricard V. Solé