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Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Problem decomposition plays a vital role when applying cooperative coevolution (CC) to large scale global optimization problems. However, most learning-based decomposition algorithms either only apply to additively separable problems or…

Neural and Evolutionary Computing · Computer Science 2021-01-20 An Chen , Zhigang Ren , Muyi Wang , Yongsheng Liang , Hanqing Liu , Wenhao Du

One of the possible objectives when designing experiments is to build or formulate a model for predicting future observations. When the primary objective is prediction, some typical approaches in the planning phase are to use…

Methodology · Statistics 2021-10-04 Trent Lemkus , Philip Ramsey , Christopher Gotwalt , Maria Weese

Decision support systems often rely on solving complex optimization problems that may require to estimate uncertain parameters beforehand. Recent studies have shown how using traditionally trained estimators for this task can lead to…

Machine Learning · Computer Science 2025-12-19 Gaetano Signorelli , Michele Lombardi

Spatial prediction refers to the estimation of unobserved values from spatially distributed observations. Although recent advances have improved the capacity to model diverse observation types, adoption in practice remains limited in…

Machine Learning · Statistics 2025-10-10 Yuta Shikuri , Hironori Fujisawa

Classical analysis of variance requires that model terms be labeled as fixed or random and typically culminate by comparing variability from each batch (factor) to variability from errors; without a standard methodology to assess the…

Methodology · Statistics 2012-07-17 Steven Geinitz , Reinhard Furrer , Stephan R. Sain

Generalizing causal estimates in randomized experiments to a broader target population is essential for guiding decisions by policymakers and practitioners in the social and biomedical sciences. While recent papers developed various…

Methodology · Statistics 2021-11-03 Melody Huang , Naoki Egami , Erin Hartman , Luke Miratrix

Pretrained VLMs exhibit strong zero-shot classification capabilities, but their predictions degrade significantly under common image corruptions. To improve robustness, many test-time adaptation (TTA) methods adopt positive data…

Machine Learning · Computer Science 2025-11-14 Ruxi Deng , Wenxuan Bao , Tianxin Wei , Jingrui He

In many real-world applications, optimization problems evolve continuously over time and are often subject to stochastic noise. We consider a stochastic time-varying optimization problem in which the objective function $f(x;t)$ changes…

Optimization and Control · Mathematics 2025-12-18 Tomoya Kamijima , Naoki Marumo , Akiko Takeda

The advantages of adaptive experiments have led to their rapid adoption in economics, other fields, as well as among practitioners. However, adaptive experiments pose challenges for causal inference. This note suggests a BOLS (batched…

Econometrics · Economics 2025-12-12 Jan Kemper , Davud Rostam-Afschar

Trial level surrogates are useful tools for improving the speed and cost effectiveness of trials, but surrogates that have not been properly evaluated can cause misleading results. The evaluation procedure is often contextual and depends on…

Methodology · Statistics 2022-08-23 Michael C Sachs , Erin E Gabriel , Alessio Crippa , Michael J Daniels

Modern statistical applications often involve minimizing an objective function that may be nonsmooth and/or nonconvex. This paper focuses on a broad Bregman-surrogate algorithm framework including the local linear approximation, mirror…

Optimization and Control · Mathematics 2021-12-20 Yiyuan She , Zhifeng Wang , Jiuwu Jin

We propose a new ensemble prediction method, Random Subset Averaging (RSA), tailored for settings with many covariates, particularly in the presence of strong correlations. RSA constructs candidate models via binomial random subset strategy…

Methodology · Statistics 2025-12-30 Wenhao Cui , Jie Hu

The novel weak-value-amplification (WVA) scheme of precision metrology is deeply rooted in the quantum nature of destructive interference between the pre- and post-selection states. And, an alternative version, termed as joint WVA (JWVA),…

Quantum Physics · Physics 2023-09-26 Jialin Li , Yazhi Niu , Xinyi Wang , Lupei Qin , Xin-Qi Li

We study the problem of model selection in causal inference, specifically for conditional average treatment effect (CATE) estimation. Unlike machine learning, there is no perfect analogue of cross-validation for model selection as we do not…

Machine Learning · Computer Science 2024-04-30 Divyat Mahajan , Ioannis Mitliagkas , Brady Neal , Vasilis Syrgkanis

Motivated by Supervised Opinion Analysis, we propose a novel framework devoted to Structured Output Learning with Abstention (SOLA). The structure prediction model is able to abstain from predicting some labels in the structured output at a…

Machine Learning · Computer Science 2019-01-16 Alexandre Garcia , Slim Essid , Chloé Clavel , Florence d'Alché-Buc

Batch effects represent a major confounder in genomic diagnostics. In copy number variant (CNV) detection from NGS, many algorithms compare read depth between test samples and a reference sample, assuming they are process-matched. When this…

Genomics · Quantitative Biology 2026-01-16 Austin Talbot , Yue Ke

The technique of data augmentation (DA) is often used in machine learning for regularization purposes to better generalize under i.i.d. settings. In this work, we present a unifying framework with topics in causal inference to make a case…

Machine Learning · Computer Science 2026-02-02 Uzair Akbar , Niki Kilbertus , Hao Shen , Krikamol Muandet , Bo Dai

Machine learning surrogates are increasingly used in engineering to accelerate costly simulations, yet distribution shifts between training and deployment often cause severe performance degradation (e.g., unseen geometries or…

Machine Learning · Computer Science 2026-02-18 Anna Zimmel , Paul Setinek , Gianluca Galletti , Johannes Brandstetter , Werner Zellinger

To date, various neural methods have been proposed for causal effect estimation based on observational data, where a default assumption is the same distribution and availability of variables at both training and inference (i.e., runtime)…

Machine Learning · Computer Science 2023-06-26 Hechuan Wen , Tong Chen , Li Kheng Chai , Shazia Sadiq , Junbin Gao , Hongzhi Yin
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