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We present a novel approach to model ultrafast time-dependent nonlinear optical polarization sensitive signals emitted from randomly-oriented molecules. By projecting the laboratory-frame analyzer polarization axis into the molecular frame…

Chemical Physics · Physics 2025-07-17 R. L. Thurston , N. Shivaram , Th. Weber , L. Z. Tan , D. S. Slaughter

In multicellular organisms, epithelial cells form layers separating compartments responsible for different physiological functions. At the early stage of epithelial layer formation, each cell of an aggregate defines an inner and an outer…

Cell Behavior · Quantitative Biology 2010-02-09 A. Veglio , A. Gamba , M. Nicodemi , F. Bussolino , G. Serini

We review the mathematical formalism underlying the modelling of stochasticity in biological systems. Beginning with a description of the system in terms of its basic constituents, we derive the mesoscopic equations governing the dynamics…

Populations and Evolution · Quantitative Biology 2012-11-05 Alan J. McKane , Tommaso Biancalani , Tim Rogers

The polarisation of cells and tissues is fundamental for tissue morphogenesis during biological development and regeneration. A deeper understanding of biological polarity pattern formation can be gained from the consideration of pattern…

Cell Behavior · Quantitative Biology 2017-10-23 Karl B. Hoffmann , Anja Voss-Böhme , Jochen C. Rink , Lutz Brusch

Cell polarization underlies many cellular processes, such as differentiation, migration, and budding. Many living cells, such as budding yeast and fission yeast, use cytoskeletal structures to actively transport proteins to one location on…

Biological Physics · Physics 2022-06-22 Harmen Wierenga , Pieter Rein ten Wolde

It has already been shown that microlensing can give rise to a non-zero variable polarisation signal. Here we use realistic simulations to demonstrate the additional information that can be gained from polarimetric observations of lensing…

Astrophysics · Physics 2009-10-30 A. M. Newsam , J. F. L. Simmons , M. A. Hendry , I. J. Coleman

We develop a simple computational model for cell boundary evolution in plastic deformation. We study the cell boundary size distribution and cell boundary misorientation distribution that experimentally have been found to have scaling forms…

Materials Science · Physics 2013-05-29 James P. Sethna , Valerie R. Coffman , Eugene Demler

The dynamics of single cell migration on flat surfaces is usually modeled by a Langevin-like problem consisting of ballistic motion for short periods and random walk. for long periods. Conversely, recent studies have revealed a previously…

Cell polarization is a critical process that separates molecular species into two distinct regions in prokaryotic and eukaryotic cells, guiding biological processes such as cell division and cell differentiation. Although several underlying…

Molecular Networks · Quantitative Biology 2025-01-28 Yixuan Chen , Guoye Guan , Lei-Han Tang , Chao Tang

The population of radio pulsars is observed to demonstrate certain polarization properties not explained by the conventional picture of pulsar polarization, namely frequency evolution of polarization, deviations of the linear polarization…

High Energy Astrophysical Phenomena · Physics 2023-08-02 Lucy Oswald , Aris Karastergiou , Simon Johnston

The skin forms an efficient barrier against the environment, and rapid cutaneous wound healing after injury is therefore essential. Healing of the uppermost layer of the skin, the epidermis, involves collective migration of keratinocytes,…

Cell Behavior · Quantitative Biology 2015-07-31 Matthias Jörg Fuhr , Michael Meyer , Eric Fehr , Gilles Ponzio , Sabine Werner , Hans Jürgen Herrmann

The calcium transport in biological systems is modelled as a reaction-diffusion process. Nonlinear calcium waves are then simulated using a stochastic cellular automaton whose rules are derived from the corresponding coupled partial…

Pattern Formation and Solitons · Physics 2010-03-30 Xin-She Yang

An electromagnetic pair-creation cascade seeded by an electron or a photon in an intense plane wave interacts in a complicated way with the external field. Many simulations neglect the vector nature of photons by including their interaction…

High Energy Physics - Phenomenology · Physics 2013-04-29 B. King , N. Elkina , H. Ruhl

Cell polarization plays a central role in the development of complex organisms. It has been recently shown that cell polarization may follow from the proximity to a phase separation instability in a bistable network of chemical reactions.…

Statistical Mechanics · Physics 2009-03-24 A. Gamba , I. Kolokolov , V. Lebedev , G. Ortenzi

The hormone auxin is actively transported throughout plants via protein machineries including the dedicated transporter known as PIN. The associated transport is ordered with nearby cells driving auxin flux in similar directions. Here we…

Tissues and Organs · Quantitative Biology 2016-04-12 Silvia Grigolon , Peter Sollich , Olivier C. Martin

In this perspective, we discuss where and how accounting for electronic many-body polarization affects the accuracy of classical molecular dynamics simulations of biomolecules.While the effects of electronic polarization are highly…

Chemical Physics · Physics 2021-03-29 Josef Melcr , Jean-Philip Piquemal

We present a novel analysis method for measurements of polarization transferred in $A(\vec{e},e'\vec{N})$ experiments, which can be applied to other kinds of polarization measurements as well. In this method the polarization transfer…

Nuclear Theory · Physics 2018-08-15 D. Izraeli , I. Mardor , E. O. Cohen , M. Duer , T. Y. Izraeli , I. Korover , J. Lichtenstadt , E. Piasetzky

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

Cell Behavior · Quantitative Biology 2018-08-02 Christèle Etchegaray , Nicolas Meunier

We present and analyse a model for cell signalling processes in biological tissues. The model includes diffusion and nonlinear reactions on the cell surfaces, and both inter- and intracellular signalling. Using techniques from the theory of…

Analysis of PDEs · Mathematics 2020-03-12 Mariya Ptashnyk , Chandrasekhar Venkataraman

Recent experiments suggest that the interplay between cells and the mechanics of their substrate gives rise to a diversity of morphological and migrational behaviors. Here, we develop a Cellular Potts Model of polarizing cells on a…