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Noninvasive brain stimulation can activate neurons in the brain but requires power electronics with exceptionally high power in the mega-volt-ampere and high frequencies in the kilohertz range. Whereas oscillator circuits offered only one…

Medical Physics · Physics 2025-03-11 Jinshui Zhang , Angel Peterchev , Stefan Goetz

Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

Neurons and Cognition · Quantitative Biology 2009-06-12 Eugenio Urdapilleta , Ines Samengo

In recent years, numerous research efforts have been dedicated towards developing efficient implantable devices for brain stimulation. However, there are limitations and challenges with the current technologies. Firstly, the stimulation of…

Fluctuation analysis is a method which allows measurement of the single channel current of ion channels even when it is too small to be resolved directly with the patch clamp technique. This is the case for voltage-gated Ca2+ channels…

Neurons and Cognition · Quantitative Biology 2017-12-13 Christian Scheppach , Hugh P. C. Robinson

Optical flow, inspired by the mechanisms of biological visual systems, calculates spatial motion vectors within visual scenes that are necessary for enabling robotics to excel in complex and dynamic working environments. However, current…

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

The spectrotemporal receptive field (STRF) provides a versatile and integrated, spectral and temporal, functional characterization of single cells in primary auditory cortex (AI). In this paper, we explore the origin of, and relationship…

Neurons and Cognition · Quantitative Biology 2007-05-23 David J. Klein , Jonathan Z. Simon , Didier A. Depireux , Shihab A. Shamma

Neuromorphic computing promises to transform AI systems by enabling them to perceive, respond to, and adapt swiftly and accurately to dynamic data and user interactions. However, traditional silicon-based and hybrid electronic technologies…

Optics · Physics 2025-07-09 Robert Otupiri , Ripalta Stabile

We study external, electrical perturbations and their responses in the brain dynamic network of the \textit{Caenorhabditis elegans} soil worm, given by the connectome of its large somatic nervous system. Our analysis is inspired by a…

Neurons and Cognition · Quantitative Biology 2016-02-17 Chris G. Antonopoulos

In the mammalian suprachiasmatic nucleus (SCN), a population of noisy cell-autonomous oscillators synchronizes to generate robust circadian rhythms at the organism-level. Within these cells two isoforms of Cryptochrome, Cry1 and Cry2,…

Molecular Networks · Quantitative Biology 2015-02-24 John H. Abel , Lukas A. Widmer , Peter C. St. John , Jörg Stelling , Francis J. Doyle

Thalamic relay cells fire action potentials that transmit information from retina to cortex. The amount of information that spike trains encode is usually estimated from the precision of spike timing with respect to the stimulus. Sensory…

In a generic neuron model, we present the linear response theory for the firing rate in response to both time dependent input currents and noise amplitudes. In both cases the signal transmission is strongly attenuated for frequencies above…

Biological Physics · Physics 2007-05-23 Bjoern Naundorf , Theo Geisel , Fred Wolf

Stochastic Resonance (SR) describes a phenomenon where an additive noise (stochastic carrier-wave) enhances the signal transmission in a nonlinear system. In the nervous system, nonlinear properties are present from the level of single ion…

Signal Processing · Electrical Eng. & Systems 2023-10-09 Weronika Potok , Onno van der Groen , Sahana Sivachelvam , Marc Bächinger , Flavio Fröhlich , Laszlo B. Kish , Nicole Wenderoth

Frequency- and time-domain Brillouin scattering spectroscopy are powerful tools to read out the mechanical properties of complex systems in material and life sciences. Indeed, coherent acoustic phonons in the time-domain method offer…

Optics · Physics 2023-01-06 Ayumu Ishijima , Shinga Okabe , Ichiro Sakuma , Keiichi Nakagawa

Drawing inspiration from the notion of cognitive incongruence associated with Stroop's famous experiment, from musical principles, and from the observation that music consumption on an individual basis is becoming increasingly ubiquitous,…

Audio and Speech Processing · Electrical Eng. & Systems 2018-11-19 Ishwarya Ananthabhotla , Joseph A. Paradiso

Given a population of interconnected input-output agents repeatedly exposed to independent random inputs, we talk of correlated variability when agents' outputs are variable (i.e., they change randomly at each input repetition) but…

Quantitative Methods · Quantitative Biology 2021-10-15 Marcela Ordorica Arango , Alessio Franci

Similar activity patterns may arise from model neural networks with distinct coupling properties and individual unit dynamics. These similar patterns may, however, respond differently to parameter variations and, specifically, to tuning of…

Neurons and Cognition · Quantitative Biology 2023-06-16 Zhuojun Yu , Jonathan E. Rubin , Peter J. Thomas

Understanding the time evolution of physical systems is crucial to revealing fundamental characteristics that are hidden in frequency domain. In optical science, high-quality resonance cavities and enhanced interactions with matters are at…

Optics · Physics 2021-09-22 Yingheng Tang , Jichao Fan , Xinwei Li , Jianzhu Ma , Minghao Qi , Cunxi Yu , Weilu Gao

Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Neurons and Cognition · Quantitative Biology 2017-12-18 Clemens Korndörfer , Ekkehard Ullner , Jordi García-Ojalvo , Gordon Pipa

Navigating multiple tasks$\unicode{x2014}$for instance in succession as in continual or lifelong learning, or in distributions as in meta or multi-task learning$\unicode{x2014}$requires some notion of adaptation. Evolution over timescales…

Machine Learning · Computer Science 2024-11-20 Sebastian Lee , Samuel Liebana , Claudia Clopath , Will Dabney
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