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Dendrites have voltage-gated ion channels which aid in production of action potentials. Thus dendrites are not just passive conductors of information, but actively act on the incoming input. Here we assume Hodgkin-Huxley formulations of…

Neurons and Cognition · Quantitative Biology 2013-09-23 Asha Gopinathan , Joseph Mathew

The cable equation is a second order, parabolic, partial differential equation that describes the evolution of voltage in the dendrite of a neuron. Here we look at the various ways in which lambda(space constant/ variable space…

Neurons and Cognition · Quantitative Biology 2013-09-10 Asha Gopinathan

The cable model is widely used in several fields of science to describe the propagation of signals. A relevant medical and biological example is the anomalous subdiffusion in spiny neuronal dendrites observed in several studies of the last…

Biological Physics · Physics 2017-06-28 Silvia Vitali , Francesco Mainardi

Dendritic processing is now considered to be important in pre-processing of signals coming into a cell. Dendrites are involved in both propagation and backpropagation of signals. In a cylindrical dendrite, signals moving in either direction…

Neurons and Cognition · Quantitative Biology 2013-09-30 Asha Gopinathan , Joseph Mathew

Progress toward characterization of structural and biophysical properties of neural dendrites together with recent findings emphasizing their role in neural computation, has propelled growing interest in refining existing theoretical models…

Mathematical Physics · Physics 2014-05-13 Juan M. Romero , Carlos Trenado

We propose an extension of the cable equation by introducing a Caputo time fractional derivative. The fundamental solutions of the most common boundary problems are derived analitically via Laplace Transform, and result be written in terms…

Biological Physics · Physics 2017-05-19 Silvia Vitali , Gastone Castellani , Francesco Mainardi

We study solutions to a recently proposed neural field model in which dendrites are modelled as a continuum of vertical fibres stemming from a somatic layer. Since voltage propagates along the dendritic direction via a cable equation with…

Analysis of PDEs · Mathematics 2024-06-25 Daniele Avitabile , Nikolai V. Chemetov , Pedro M. Lima

Different experimental studies have reported anomalous diffusion in brain tissues and notably this anomalous diffusion is expressed through fractional derivatives. Axons are important to understand neurodegenerative diseases such as…

Neurons and Cognition · Quantitative Biology 2017-09-27 Erick J. López-Sánchez , Juan M. Romero , Huitzilin Yépez-Martínez

Neurons are spatially extended structures that receive and process inputs on their dendrites. It is generally accepted that neuronal computations arise from the active integration of synaptic inputs along a dendrite between the input…

Neurons and Cognition · Quantitative Biology 2013-09-11 Willem A. M. Wybo , Klaus M. Stiefel , Benjamin Torben-Nielsen

This paper presents a numerically exact cable finite element model for static nonlinear analysis of cable structures. The model derives the exact expression of the tension field using the geometrically exact beam theory coupled with the…

Computational Engineering, Finance, and Science · Computer Science 2025-05-20 Wenxiong Li , Qikun Huang , Suiyin Chen

Mesoscopic systems and large molecules are often modeled by graphs of one-dimensional wires, connected at vertices. In this paper we discuss the solutions of the Schr\"odinger equation on such graphs, which have been named "quantum…

Mesoscale and Nanoscale Physics · Physics 2020-04-01 Amnon Aharony , Ora Entin-Wohlman

Signal propagation in neuronal dendrites represents the basis for interneuron communication and information processing in the brain. Here we take into account charge inhomogeneities arising in the vicinity of ion channels in cytoplasm and…

Neurons and Cognition · Quantitative Biology 2013-12-25 Ivan A. Lazarevich , Victor B. Kazantsev

We introduce suitable coordinate systems for pipes and their variants that allow us to transform partial differential equations (PDEs) on the pipe surfaces or in the solid pipes into computational domains with fixed limits/ranges. Such a…

Numerical Analysis · Mathematics 2025-09-09 Shuaifei Hu , Yujian Jiao , Desong Kong , Li-Lian Wang

A single neuron receives an extensive array of synaptic inputs through its dendrites, raising the fundamental question of how these inputs undergo integration and summation, culminating in the initiation of spikes in the soma. Experimental…

Neurons and Cognition · Quantitative Biology 2025-04-30 Yuanhong Tang , Shanshan Jia , Tiejun Huang , Zhaofei Yu , Jian K. Liu

The cable-trench problem is defined as a linear combination of the shortest path and the minimum spanning tree problem. In particular, the goal is to find a spanning tree that simultaneously minimizes its total length and the total path…

Optimization and Control · Mathematics 2023-12-22 Lara Löhken , Michael Stiglmayr

Intracellular recordings of cortical neurons in vivo display intense subthreshold membrane potential (Vm) activity. The power spectral density (PSD) of the Vm displays a power-law structure at high frequencies (>50 Hz) with a slope of about…

Neurons and Cognition · Quantitative Biology 2009-11-13 Claude Bedard , Alain Destexhe

We apply two families of novel fractional $\theta$-methods, the FBT-$\theta$ and FBN-$\theta$ methods developed by the authors in previous work, to the fractional Cable model, in which the time direction is approximated by the fractional…

Numerical Analysis · Mathematics 2020-06-11 Baoli Yin , Yang Liu , Hong Li , Zhimin Zhang

The neural network method of solving differential equations is used to approximate the electric potential and corresponding electric field in the slit-well microfluidic device. The device's geometry is non-convex, making this a challenging…

Computational Physics · Physics 2020-07-29 Martin Magill , Andrew M. Nagel , Hendrick W. de Haan

This paper presents a spike-based model which employs neurons with functionally distinct dendritic compartments for classifying high dimensional binary patterns. The synaptic inputs arriving on each dendritic subunit are nonlinearly…

Neural and Evolutionary Computing · Computer Science 2014-11-26 Shaista Hussain , Shih-Chii Liu , Arindam Basu

The aim of this paper is the derivation of structure preserving schemes for the solution of the EPDiff equation, with particular emphasis on the two dimensional case. We develop three different schemes based on the Discrete Variational…

Analysis of PDEs · Mathematics 2016-04-26 Stig Larsson , Takayasu Matsuo , Klas Modin , Matteo Molteni
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