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Evolutionary games on graphs play an important role in the study of evolution of cooperation in applied biology. Using rigorous mathematical concepts from a dynamical systems and graph theoretical point of view, we formalize the notions of…

Dynamical Systems · Mathematics 2014-11-18 Jeremias Epperlein , Stefan Siegmund , Petr Stehlík

Directed evolution as a widely-used engineering strategy faces obstacles in finding desired mutants from the massive size of candidate modifications. While deep learning methods learn protein contexts to establish feasible searching space,…

Quantitative Methods · Quantitative Biology 2023-04-18 Bingxin Zhou , Outongyi Lv , Kai Yi , Xinye Xiong , Pan Tan , Liang Hong , Yu Guang Wang

Graphs are fundamental mathematical structures used in various fields to represent data, signals and processes. In this paper, we propose a novel framework for learning/estimating graphs from data. The proposed framework includes (i)…

Machine Learning · Computer Science 2017-07-07 Hilmi E. Egilmez , Eduardo Pavez , Antonio Ortega

Inspired by recent works on evolutionary graph theory, an area of growing interest in mathematical and computational biology, we present the first known examples of undirected structures acting as suppressors of selection for any fitness…

Populations and Evolution · Quantitative Biology 2017-11-01 Fernando Alcalde Cuesta , Pablo González Sequeiros , Álvaro Lozano Rojo

Uncertainty estimation in deep models is essential in many real-world applications and has benefited from developments over the last several years. Recent evidence suggests that existing solutions dependent on simple Gaussian formulations…

Machine Learning · Computer Science 2022-05-11 Jurijs Nazarovs , Ronak R. Mehta , Vishnu Suresh Lokhande , Vikas Singh

There is a rising need for computational models that can complementarily leverage data of different modalities while investigating associations between subjects for population-based disease analysis. Despite the success of convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Yongxiang Huang , Albert C. S. Chung

he greatest weakness of evolutionary algorithms, widely used today, is the premature convergence due to the loss of population diversity over generations. To overcome this problem, several algorithms have been proposed, such as the…

Neural and Evolutionary Computing · Computer Science 2019-08-22 Asmaa Ghoumari , Amir Nakib

Evolutionary graph theory models the effects of natural selection and random drift on structured populations of competing mutant and non-mutant individuals. Recent studies have found that fixation times in such systems often have…

Populations and Evolution · Quantitative Biology 2019-07-31 David Hathcock , Steven H. Strogatz

Evolution occurs in populations of reproducing individuals. It is well known that population structure can affect evolutionary dynamics. Traditionally, natural selection is studied between mutants that differ in reproductive rate, but are…

Populations and Evolution · Quantitative Biology 2021-11-23 Josef Tkadlec , Kamran Kaveh , Krishnendu Chatterjee , Martin A. Nowak

Community detection is an important tool for analyzing the social graph of mobile phone users. The problem of finding communities in static graphs has been widely studied. However, since mobile social networks evolve over time, static graph…

Social and Information Networks · Computer Science 2013-12-04 Carlos Sarraute , Gervasio Calderon

We focus on evolution equations on co-evolving, infinite, graphs and establish a rigorous link with a class of nonlinear continuity equations, whose vector fields depend on the graphs considered. More precisely, weak solutions of the…

Analysis of PDEs · Mathematics 2025-04-15 José Antonio Carrillo , Antonio Esposito , László Mikolás

Graphs are fundamental data structures which concisely capture the relational structure in many important real-world domains, such as knowledge graphs, physical and social interactions, language, and chemistry. Here we introduce a powerful…

Machine Learning · Computer Science 2018-03-12 Yujia Li , Oriol Vinyals , Chris Dyer , Razvan Pascanu , Peter Battaglia

We study two of the simple rules on finite graphs under the death-birth updating and the imitation updating discovered by Ohtsuki, Hauert, Lieberman and Nowak [Nature 441 (2006) 502-505]. Each rule specifies a payoff-ratio cutoff point for…

Probability · Mathematics 2015-03-19 Yu-Ting Chen

Fitting a graphical model to a collection of random variables given sample observations is a challenging task if the observed variables are influenced by latent variables, which can induce significant confounding statistical dependencies…

Machine Learning · Statistics 2020-10-20 Armeen Taeb , Parikshit Shah , Venkat Chandrasekaran

Evolutionary dynamics have been traditionally studied in the context of homogeneous populations, mainly described my the Moran process. Recently, this approach has been generalized in \cite{LHN} by arranging individuals on the nodes of a…

Discrete Mathematics · Computer Science 2012-06-22 George B. Mertzios , Sotiris Nikoletseas , Christoforos Raptopoulos , Paul G. Spirakis

We develop approximate estimation methods for exponential random graph models (ERGMs), whose likelihood is proportional to an intractable normalizing constant. The usual approach approximates this constant with Monte Carlo simulations,…

Methodology · Statistics 2023-01-11 Angelo Mele , Lingjiong Zhu

Graphs with diverse structural characteristics play a central role in modelling and optimization tasks. The ability to generate different types of graphs that exhibit shared properties is likewise essential for algorithm selection and…

Neural and Evolutionary Computing · Computer Science 2026-03-31 Hendrik Richter , Frank Neumann

We consider the classic Moran process modeling the spread of genetic mutations, as extended to structured populations by Lieberman et al.\ (Nature, 2005). In this process, individuals are the vertices of a connected graph $G$. Initially,…

Discrete Mathematics · Computer Science 2016-11-08 George Giakkoupis

We study the influence of complex graphs on the metastability and fixation properties of a set of evolutionary processes. In the framework of evolutionary game theory, where the fitness and selection are frequency-dependent and vary with…

Statistical Mechanics · Physics 2012-11-01 Michael Assaf , Mauro Mobilia

Natural selection and random drift are competing phenomena for explaining the evolution of populations. Combining a highly fit mutant with a population structure that improves the odds that the mutant spreads through the whole population…

Populations and Evolution · Quantitative Biology 2009-08-14 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza