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The high fraction of published results that turn out to be incorrect is a major concern of today's science. This paper contributes to the understanding of this problem in two independent directions. First, Johnson's recent claim that…

Applications · Statistics 2014-11-07 Jean-Christophe Mourrat

P-hacking poses challenges to traditional hypothesis testing. In this paper, we propose a robust method for the one-sample significance test that can protect against p-hacking from sample manipulation. Precisely, assuming a sequential…

Statistics Theory · Mathematics 2025-02-18 Xifeng Li , Shuzhen Yang , Jianfeng Yao

In scientific inference problems, the underlying statistical modeling assumptions have a crucial impact on the end results. There exist, however, only a few automatic means for validating these fundamental modelling assumptions. The…

Methodology · Statistics 2019-05-21 Andreas Svensson , Dave Zachariah , Petre Stoica , Thomas B. Schön

A definition for the statistical significance by constructing a correlation between the normal distribution integral probability and the p-value observed in an experiment is proposed, which is suitable for both counting experiment and…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Yongsheng Zhu

In High-Energy Physics experiments it is often necessary to evaluate the global statistical significance of apparent resonances observed in invariant mass spectra. One approach to determining significance is to use simulated events to find…

Data Analysis, Statistics and Probability · Physics 2023-12-29 Kelly J Yi , Leonard G Spiegel , Zhen Hu

This work is motivated by learning the individualized minimal clinically important difference, a vital concept to assess clinical importance in various biomedical studies. We formulate the scientific question into a high-dimensional…

Methodology · Statistics 2023-03-28 Huijie Feng , Jingyi Duan , Yang Ning , Jiwei Zhao

Given a multiple testing situation, the null hypotheses that appear to have sufficiently low probabilities of truth may be rejected using a simple, nonparametric method of decision theory. This applies not only to posterior levels of…

Probability · Mathematics 2025-10-20 David R. Bickel

Practical problems with missing data are common, and statistical methods have been developed concerning the validity and/or efficiency of statistical procedures. On a central focus, there have been longstanding interests on the mechanism…

Methodology · Statistics 2020-03-26 Rui Duan , C. Jason Liang , Pamela Shaw , Cheng Yong Tang , Yong Chen

A {\it pure significance test} (PST) tests a simple null hypothesis $H_f:Y\sim f$ {\it without specifying an alternative hypothesis} by rejecting $H_f$ for {\it small} values of $f(Y)$. When the sample space supports a proper uniform pmf…

Statistics Theory · Mathematics 2024-04-23 Michael D. Perlman

Significance testing aims to determine whether a proposition about the population distribution is the truth or not given observations. However, traditional significance testing often needs to derive the distribution of the testing…

Machine Learning · Statistics 2024-01-25 Zehua Liu , Zimeng Li , Jingyuan Wang , Yue He

When statisticians quarrel about hypothesis testing, the debate usually focus on which method is the correct one. The fundamental question of whether we should test hypothesis at all tends to be forgotten. This lack of debate has its roots…

Other Statistics · Statistics 2016-11-22 André C. R. Martins

There is a general agreement that it is important to consider the practical relevance of an effect in addition to its statistical significance, yet a formal definition of practical relevance is still pending and shall be provided within…

Methodology · Statistics 2021-10-20 Patrick Schwaferts , Thomas Augustin

I present a critique of the methods used in a typical paper. This leads to three broad conclusions about the conventional use of statistical methods. First, results are often reported in an unnecessarily obscure manner. Second, the null…

Applications · Statistics 2013-03-05 Michael Wood

Recent works have extended notions of feature importance to semantic concepts that are inherently interpretable to the users interacting with a black-box predictive model. Yet, precise statistical guarantees, such as false positive rate and…

Machine Learning · Statistics 2024-10-08 Jacopo Teneggi , Jeremias Sulam

A statistical test based on the geometric mean is proposed to determine if a predictive model should be rejected or not, when the quantity of interest is a strictly positive continuous random variable. A simulation study is performed to…

Methodology · Statistics 2015-10-27 Arturo Erdely

To properly estimate signal significance while accounting for both statistical and systematic uncertainties, we conducted a study to analyze the impact of typical systematic uncertainties, such as background shape, signal shape, and the…

Data Analysis, Statistics and Probability · Physics 2023-12-19 Yi Ding , Weiming Song , Kai Zhu

Importance sampling approximates expectations with respect to a target measure by using samples from a proposal measure. The performance of the method over large classes of test functions depends heavily on the closeness between both…

Computation · Statistics 2016-09-01 Daniel Sanz-Alonso

A researcher is interested in what sample size is needed to get the required significance of the same test, assuming exactly the same situation that was in the study with the non-significant result. We propose a simple solution to the…

Methodology · Statistics 2022-10-31 I. Novikov , I. Tessler , A. Yakirevich

In science and medicine, model interpretations may be reported as discoveries of natural phenomena or used to guide patient treatments. In such high-stakes tasks, false discoveries may lead investigators astray. These applications would…

Machine Learning · Statistics 2020-08-18 Collin Burns , Jesse Thomason , Wesley Tansey

A definition for the statistical significance of a signal in an experiment is proposed by establishing a correlation between the observed p-value and the normal distribution integral probability, which is suitable for both counting…

Data Analysis, Statistics and Probability · Physics 2009-02-20 Yong-Sheng Zhu