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Mass spectrometry provides a high-throughput way to identify proteins in biological samples. In a typical experiment, proteins in a sample are first broken into their constituent peptides. The resulting mixture of peptides is then subjected…

Applications · Statistics 2010-11-10 Qunhua Li , Michael J. MacCoss , Matthew Stephens

Spectral clustering is a popular method for community detection in network graphs: starting from a matrix representation of the graph, the nodes are clustered on a low dimensional projection obtained from a truncated spectral decomposition…

Machine Learning · Statistics 2022-08-10 Francesco Sanna Passino , Nicholas A. Heard , Patrick Rubin-Delanchy

We present an unsupervised data processing workflow that is specifically designed to obtain a fast conformational clustering of long molecular dynamics simulation trajectories. In this approach we combine two dimensionality reduction…

Chemical Physics · Physics 2023-08-09 Simon Hunkler , Kay Diederichs , Oleksandra Kukharenko , Christine Peter

Cluster analysis faces two problems in high dimensions: first, the `curse of dimensionality' that can lead to overfitting and poor generalization performance; and second, the sheer time taken for conventional algorithms to process large…

Quantitative Methods · Quantitative Biology 2013-09-12 Shabnam N. Kadir , Dan F. M. Goodman , Kenneth D. Harris

Spectral clustering has shown a superior performance in analyzing the cluster structure. However, its computational complexity limits its application in analyzing large-scale data. To address this problem, many low-rank matrix approximating…

Machine Learning · Computer Science 2020-07-23 Djallel Bouneffouf

We propose a Classification Via Clustering (CVC) algorithm which enables existing clustering methods to be efficiently employed in classification problems. In CVC, training and test data are co-clustered and class-cluster distributions are…

Computer Vision and Pattern Recognition · Computer Science 2014-09-29 Arif Mahmood , Ajmal S. Mian

We present a structural clustering algorithm for large-scale datasets of small labeled graphs, utilizing a frequent subgraph sampling strategy. A set of representatives provides an intuitive description of each cluster, supports the…

Databases · Computer Science 2016-10-03 Till Schäfer , Petra Mutzel

Clustering in image analysis is a central technique that allows to classify elements of an image. We describe a simple clustering technique that uses the method of similarity matrices. We expand upon recent results in spectral analysis for…

Statistics Theory · Mathematics 2022-03-23 Denis Gaidashev , Ralf Pihlström , Martin Ryner

Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

The huge amount of data acquired by high-throughput sequencing requires data reduction for effective analysis. Here we give a clustering algorithm for genome-wide open chromatin data using a new data reduction method. This method regards…

Genomics · Quantitative Biology 2024-10-14 Azusa Tanaka , Yasuhiro Ishitsuka , Hiroki Ohta , Akihiro Fujimoto , Jun-ichirou Yasunaga , Masao Matsuoka

Algorithms for community detection are usually stochastic, leading to different partitions for different choices of random seeds. Consensus clustering has proven to be an effective technique to derive more stable and accurate partitions…

Physics and Society · Physics 2019-04-23 Aditya Tandon , Aiiad Albeshri , Vijey Thayananthan , Wadee Alhalabi , Santo Fortunato

In computer vision, the estimation of the fundamental matrix is a basic problem that has been extensively studied. The accuracy of the estimation imposes a significant influence on subsequent tasks such as the camera trajectory…

Computer Vision and Pattern Recognition · Computer Science 2015-04-15 Hao Wu , Yi Wan

Clustering is a critical component of decision-making in todays data-driven environments. It has been widely used in a variety of fields such as bioinformatics, social network analysis, and image processing. However, clustering accuracy…

Machine Learning · Computer Science 2025-07-14 Krishnendu Das , Sumit Gupta , Awadhesh Kumar

Clustering multidimensional points is a fundamental data mining task, with applications in many fields, such as astronomy, neuroscience, bioinformatics, and computer vision. The goal of clustering algorithms is to group similar objects…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-22 Yihao Huang , Shangdi Yu , Julian Shun

We propose the DPSM method, a density-based node clustering approach that automatically determines the number of clusters and can be applied in both data space and graph space. Unlike traditional density-based clustering methods, which…

Machine Learning · Computer Science 2024-11-05 Feiping Nie , Yitao Song , Jingjing Xue , Rong Wang , Xuelong Li

One of the challenges of high granularity calorimeters, such as that to be built to cover the endcap region in the CMS Phase-2 Upgrade for HL-LHC, is that the large number of channels causes a surge in the computing load when clustering…

Instrumentation and Detectors · Physics 2020-01-29 Marco Rovere , Ziheng Chen , Antonio Di Pilato , Felice Pantaleo , Chris Seez

Scale invariance (fractality) is a prominent feature of the large-scale behavior of many stochastic systems. In this work, we construct an algorithm for the statistical identification of the Hurst distribution (in particular, the scaling…

Methodology · Statistics 2025-01-31 Patrice Abry , Gustavo Didier , Oliver Orejola , Herwig Wendt

With rapidly increasing data, clustering algorithms are important tools for data analytics in modern research. They have been successfully applied to a wide range of domains; for instance, bioinformatics, speech recognition, and financial…

Data Structures and Algorithms · Computer Science 2015-12-01 Ka-Chun Wong

We propose a simple and efficient clustering method for high-dimensional data with a large number of clusters. Our algorithm achieves high-performance by evaluating distances of datapoints with a subset of the cluster centres. Our…

Machine Learning · Computer Science 2022-03-30 Georgios Exarchakis , Omar Oubari , Gregor Lenz

This paper focuses on scalability and robustness of spectral clustering for extremely large-scale datasets with limited resources. Two novel algorithms are proposed, namely, ultra-scalable spectral clustering (U-SPEC) and ultra-scalable…

Machine Learning · Computer Science 2019-03-06 Dong Huang , Chang-Dong Wang , Jian-Sheng Wu , Jian-Huang Lai , Chee-Keong Kwoh