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In recent years machine learning (ML) took bio- and cheminformatics fields by storm, providing new solutions for a vast repertoire of problems related to protein sequence, structure, and interactions analysis. ML techniques, deep neural…

Biomolecules · Quantitative Biology 2020-03-31 Marta M. Stepniewska-Dziubinska , Piotr Zielenkiewicz , Pawel Siedlecki

As Transformers have become state-of-the-art models for natural language processing (NLP) tasks, the need to understand and explain their predictions is increasingly apparent. Especially in unsupervised applications, such as information…

Computation and Language · Computer Science 2024-05-13 Alexandros Vasileiou , Oliver Eberle

How pattern and form are generated in a reproducible manner during embryogenesis remains poorly understood. Intestinal organoid morphogenesis involves a number of mechanochemical regulators, including cell-type specific cytoskeletal forces…

Tissues and Organs · Quantitative Biology 2024-04-01 Shi-Lei Xue , Qiutan Yang , Prisca Liberali , Edouard Hannezo

Central pattern generators (CPGs), with a basis is neurophysiological studies, are a type of neural network for the generation of rhythmic motion. While CPGs are being increasingly used in robot control, most applications are hand-tuned for…

Neural and Evolutionary Computing · Computer Science 2015-03-13 Atilim Gunes Baydin

Modular exponentiation is crucial to number theory and cryptography, yet remains largely unexplored from a mechanistic interpretability standpoint. We train a 4-layer encoder-decoder Transformer model to perform this operation and…

Machine Learning · Computer Science 2025-10-24 David Demitri Africa , Sara M. Kapoor , Theo Simon Sorg , Challenger Mishra

The aim of this paper is to develop suitable models for the phenomenon of cell blebbing, which allow for computational predictions of mechanical effects including the crucial interaction of the cell membrane and the actin cortex. For this…

Cell Behavior · Quantitative Biology 2021-07-15 Philipp Werner , Martin Burger , Florian Frank , Harald Garcke

Collocated tactile sensing is a fundamental enabling technology for dexterous manipulation. However, deformable sensors introduce complex dynamics between the robot, grasped object, and environment that must be considered for fine…

Robotics · Computer Science 2022-09-28 Miquel Oller , Mireia Planas , Dmitry Berenson , Nima Fazeli

Structure-based drug design (SBDD) aims to generate 3D ligand molecules that bind to specific protein targets. Existing 3D deep generative models including diffusion models have shown great promise for SBDD. However, it is complex to…

Biomolecules · Quantitative Biology 2024-03-01 Zhilin Huang , Ling Yang , Zaixi Zhang , Xiangxin Zhou , Yu Bao , Xiawu Zheng , Yuwei Yang , Yu Wang , Wenming Yang

Robots engaged in complex manipulation tasks require robust material property recognition to ensure adaptability and precision. Traditionally, visual data has been the primary source for object perception; however, it often proves…

Robotics · Computer Science 2025-01-28 Hengxu You , Tianyu Zhou , Jing Du

Termites which are able to forage in the open can be often seen, in the field or in the lab: (i) wandering around, forming no observable pattern, or (ii) clustering themselves in a dense and almost immobile pack, or (iii) milling about in a…

Populations and Evolution · Quantitative Biology 2025-05-15 Leticia R. Paiva , Sidiney G. Alves , Og DeSouza , Octavio Miramontes

Legged locomotion is a challenging task in the field of robotics but a rather simple one in nature. This motivates the use of biological methodologies as solutions to this problem. Central pattern generators are neural networks that are…

Neural and Evolutionary Computing · Computer Science 2020-03-18 Elie Aljalbout , Florian Walter , Florian Röhrbein , Alois Knoll

DNA, RNA and proteins are among the most important macromolecules in a living cell. These molecules are polymerized by molecular machines. These natural nano-machines polymerize such macromolecules, adding one monomer at a time, using…

Biological Physics · Physics 2013-01-01 Ajeet K. Sharma , Debashish Chowdhury

It is well known that the twinning is an important mode of plastic deformation in nanocrystalline materials. As a result, it is expected that the twin can interact with different grain boundaries (GBs) during the plastic deformation.…

Materials Science · Physics 2022-05-03 G. Sainath , A. Nagesha

Biological systems are majorly dependent on their property of bistability in order to exhibit nongenetic heterogeneity in terms of cellular morphology and physiology. Spatial patterns of phenotypically heterogeneous cells, arising due to…

Quantitative Methods · Quantitative Biology 2023-01-25 Priya Chakraborty , Ushasi Roy , Mohit K. Jolly , Sayantari Ghosh

Confinement properties of the $1+1$ Schwinger model can bestudied by computing the string tension between two charges. It is finite (vanishing) if the fermions are massive (massless) corresponding to the occurrence of confinement…

High Energy Physics - Theory · Physics 2019-08-28 Joao C. Pinto Barros , Marcello Dalmonte , Andrea Trombettoni

We present (Experience-Modulated Biologically-inspired Emergent Reasoning), a hybrid cognitive architecture that reorganises the relationship between large language models (LLMs) and memory: rather than augmenting an LLM with retrieval…

Artificial Intelligence · Computer Science 2026-04-15 William Savage

Molecular Communications (MC) underpins signaling in biological systems, enabling information transfer through biochemical molecules. The prospect of engineering this natural communication mechanism has inspired the Internet of Bio-Nano…

Emerging Technologies · Computer Science 2023-05-12 Murat Kuscu

This essay is a recapitulation of an earlier Kramers-Kronig analysis of biological tissue, published in 2010, "Kramers-Kronig analysis of biological skin". The intent is to both complement and bolster the antecedent analysis by furnishing…

Tissues and Organs · Quantitative Biology 2011-12-22 Luisiana X. Cundin

Adhesion processes of biological membranes that enclose cells and cellular organelles are essential for immune responses, tissue formation, and signaling. These processes depend sensitively on the binding constant K2D of the…

Biomolecules · Quantitative Biology 2015-11-30 Guang-Kui Xu , Jinglei Hu , Reinhard Lipowsky , Thomas R. Weikl

Sequence modelling requires determining which past tokens are causally relevant from the context and their importance: a process inherent to the attention layers in transformers, yet whose underlying learned mechanisms remain poorly…

Machine Learning · Computer Science 2026-04-14 Francesco D'Angelo , Nicolas Flammarion