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Directed evolution as a widely-used engineering strategy faces obstacles in finding desired mutants from the massive size of candidate modifications. While deep learning methods learn protein contexts to establish feasible searching space,…

Quantitative Methods · Quantitative Biology 2023-04-18 Bingxin Zhou , Outongyi Lv , Kai Yi , Xinye Xiong , Pan Tan , Liang Hong , Yu Guang Wang

Spectral bias, the tendency of neural networks to learn low-frequency features first, is a well-known issue with many training algorithms for physics-informed neural networks (PINNs). To overcome this issue, we propose IFeF-PINN, an…

Machine Learning · Computer Science 2025-10-23 Yulun Wu , Miguel Aguiar , Karl H. Johansson , Matthieu Barreau

Most machine vision tasks (e.g., semantic segmentation) are based on images encoded and decoded by image compression algorithms (e.g., JPEG). However, these decoded images in the pixel domain introduce distortion, and they are optimized for…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Jinming Liu , Heming Sun , Jiro Katto

Weight Space Learning (WSL), which frames neural network weights as a data modality, is an emerging field with potential for tasks like meta-learning or transfer learning. Particularly, Implicit Neural Representations (INRs) provide a…

Machine Learning · Computer Science 2026-02-02 Tianming Qiu , Christos Sonis , Hao Shen

While the deployment of neural networks, yielding impressive results, becomes more prevalent in various applications, their interpretability and understanding remain a critical challenge. Network inversion, a technique that aims to…

Machine Learning · Computer Science 2024-02-20 Pirzada Suhail , Supratik Chakraborty , Amit Sethi

Although quantum machine learning has shown great promise, the practical application of quantum computers remains constrained in the noisy intermediate-scale quantum era. To take advantage of quantum machine learning, we investigate the…

Quantum Physics · Physics 2026-02-20 Shaozhi Li , M Sabbir Salek , Mashrur Chowdhury , Yao Wang

Existing information retrieval systems are largely constrained by their reliance on vector inner products to assess query-document relevance, which naturally limits the expressiveness of the relevance score they can produce. We propose a…

Information Retrieval · Computer Science 2025-05-02 Julian Killingback , Hansi Zeng , Hamed Zamani

Neural networks have emerged as powerful tools across various applications, yet their decision-making process often remains opaque, leading to them being perceived as "black boxes." This opacity raises concerns about their interpretability…

Machine Learning · Computer Science 2024-11-27 Pirzada Suhail , Amit Sethi

We analyze the expressivity of a universal deep neural network that can be organized as a series of nested qubit rotations, accomplished by adjustable data re-uploads. While the maximal expressive power increases with the depth of the…

Quantum Physics · Physics 2023-11-13 Iván Panadero , Yue Ban , Hilario Espinós , Ricardo Puebla , Jorge Casanova , Erik Torrontegui

We present a simple non-generative approach to deep representation learning that seeks equivariant deep embedding through simple objectives. In contrast to existing equivariant networks, our transformation coding approach does not constrain…

Machine Learning · Computer Science 2022-02-23 Mehran Shakerinava , Arnab Kumar Mondal , Siamak Ravanbakhsh

Masked Image Modeling (MIM) has garnered significant attention in self-supervised learning, thanks to its impressive capacity to learn scalable visual representations tailored for downstream tasks. However, images inherently contain…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Wenzhao Xiang , Chang Liu , Hongyang Yu , Xilin Chen

After the tremendous development of neural networks trained by backpropagation, it is a good time to develop other algorithms for training neural networks to gain more insights into networks. In this paper, we propose a new algorithm for…

Machine Learning · Computer Science 2020-07-01 Benyamin Ghojogh , Fakhri Karray , Mark Crowley

Inverse problems exist in many domains such as phase imaging, image processing, and computer vision. These problems are often solved with application-specific algorithms, even though their nature remains the same: mapping input image(s) to…

Computational Physics · Physics 2021-10-22 Feng Wang , Alberto Eljarrat , Johannes Müller , Trond Henninen , Erni Rolf , Christoph Koch

Real-world data typically contain repeated and periodic patterns. This suggests that they can be effectively represented and compressed using only a few coefficients of an appropriate basis (e.g., Fourier, Wavelets, etc.). However, distance…

Machine Learning · Statistics 2014-05-26 Michail Vlachos , Nikolaos Freris , Anastasios Kyrillidis

The state-of-the-art performance for several real-world problems is currently reached by convolutional neural networks (CNN). Such learning models exploit recent results in the field of deep learning, typically leading to highly performing,…

Machine Learning · Computer Science 2021-08-31 Giosuè Cataldo Marinò , Alessandro Petrini , Dario Malchiodi , Marco Frasca

In this paper, we prove the representation defects of a cascaded convolutional decoder network, considering the capacity of representing different frequency components of an input sample. We conduct the discrete Fourier transform on each…

Machine Learning · Computer Science 2023-12-04 Ling Tang , Wen Shen , Zhanpeng Zhou , Yuefeng Chen , Quanshi Zhang

As machine learning systems get widely adopted for high-stake decisions, quantifying uncertainty over predictions becomes crucial. While modern neural networks are making remarkable gains in terms of predictive accuracy, characterizing…

Machine Learning · Computer Science 2019-06-14 Melanie F. Pradier , Weiwei Pan , Jiayu Yao , Soumya Ghosh , Finale Doshi-velez

Deep neural networks are usually trained in the space of the nodes, by adjusting the weights of existing links via suitable optimization protocols. We here propose a radically new approach which anchors the learning process to reciprocal…

Machine Learning · Computer Science 2021-04-14 Lorenzo Giambagli , Lorenzo Buffoni , Timoteo Carletti , Walter Nocentini , Duccio Fanelli

We investigate neural network image reconstruction for magnetic particle imaging. The network performance depends strongly on the convolution effects of the spectrum input data. The larger convolution effect appearing at a relatively…

Medical Physics · Physics 2017-09-25 Byung Gyu Chae

Feature extraction in noisy image datasets presents many challenges in model reliability. In this paper, we use the discrete Fourier transform in conjunction with persistent homology analysis to extract specific frequencies that correspond…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Anil Chintapalli , Peter Tenholder , Henry Chen , Arjun Rao