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A coarse-grained computational procedure based on the Finite Element Method is proposed to calculate the normal modes and mechanical response of proteins and their supramolecular assemblies. Motivated by the elastic network model, proteins…

Biomolecules · Quantitative Biology 2007-05-23 Mark Bathe

We study the brittle fragmentation of spheres by using a three-dimensional Discrete Element Model. Large scale computer simulations are performed with a model that consists of agglomerates of many particles, interconnected by beam-truss…

Statistical Mechanics · Physics 2009-11-13 H. A. Carmona , F. K. Wittel , F. Kun , H. J. Herrmann

As an alternative to solving of Poisson equation in Particle-in-Cell methods, a new construction of current density exactly satisfying continuity equation in finite differences is developed. This procedure called density decomposition is…

Computational Physics · Physics 2007-05-23 Timur Zh. Esirkepov

Current state-of-the-art instance segmentation methods are not suited for real-time applications like autonomous driving, which require fast execution times at high accuracy. Although the currently dominant proposal-based methods have high…

Computer Vision and Pattern Recognition · Computer Science 2019-08-05 Davy Neven , Bert De Brabandere , Marc Proesmans , Luc Van Gool

We consider the problem of computing first-passage time distributions for reaction processes modelled by master equations. We show that this generally intractable class of problems is equivalent to a sequential Bayesian inference problem…

Computational Physics · Physics 2017-11-29 David Schnoerr , Botond Cseke , Ramon Grima , Guido Sanguinetti

Linear rate equations are used to describe the cascading decay of an initial heavy cluster into fragments. We consider moments of arbitrary orders of the mass multiplicity spectrum and derive scaling properties pertaining to their time…

Nuclear Theory · Physics 2008-11-26 B. G. Giraud , R. Peschanski

Many aspects of the study of protein folding and dynamics have been affected by the recent advances in machine learning. Methods for the prediction of protein structures from their sequences are now heavily based on machine learning tools.…

Biological Physics · Physics 2019-11-25 Frank Noé , Gianni De Fabritiis , Cecilia Clementi

Developing new methods for the accurate and efficient calculations of real-time quantum correlation functions is deemed one of the most challenging problems of modern condensed matter theory. Many popular methods, such as centroid molecular…

Chemical Physics · Physics 2025-10-16 Nathan London , Mohammad R. Momeni

We use Smoothed Particle Hydrodynamic simulations of cold, uniform density, self-gravitating filaments, to investigate their longitudinal collapse timescales; these timescales are important because they determine the time available for a…

Solar and Stellar Astrophysics · Physics 2015-03-30 Seamus D. Clarke , Anthony P. Whitworth

Protein characterization is one of the key components for understanding the human body and advancing drug discovery processes. While the future of quantum hardware holds the potential to accurately characterize these molecules, current…

Quantum Physics · Physics 2025-05-05 Laia Coronas Sala , Parfait Atchade-Adelemou

Efficient long-time integration of nonlinear fractional differential equations is significantly challenging due to the integro-differential nature of the fractional operators. In addition, the inherent non-smoothness introduced by the…

Numerical Analysis · Mathematics 2019-09-11 Yongtao Zhou , Jorge L. Suzuki , Chengjian Zhang , Mohsen Zayernouri

The problem of recovering a moment-determinate multivariate function $f$ via its moment sequence is studied. Under mild conditions on $f$, the point-wise and $L_1$-rates of convergence for the proposed constructions are established. The…

Statistics Theory · Mathematics 2023-12-08 Robert Mnatsakanov , Rafik Aramyan , Farhad Jafari

Image segmentation is a long-standing challenge in computer vision, studied continuously over several decades, as evidenced by seminal algorithms such as N-Cut, FCN, and MaskFormer. With the advent of foundation models (FMs), contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Tianfei Zhou , Wang Xia , Fei Zhang , Boyu Chang , Wenguan Wang , Ye Yuan , Ender Konukoglu , Daniel Cremers

This work proposes stochastic partial differential equations (SPDEs) as a practical tool to replicate clustering effects of more detailed particle-based dynamics. Inspired by membrane-mediated receptor dynamics on cell surfaces, we…

Quantitative Methods · Quantitative Biology 2025-01-22 Nathalie Wehlitz , Mohsen Sadeghi , Alberto Montefusco , Christof Schütte , Grigorios A. Pavliotis , Stefanie Winkelmann

A simplified nonlinear memory function is proposed in the ideal time-convolutionless mode-coupling theory equation to study the dynamics of glass-forming liquids. The numerical solutions are then compared with the simulation results…

Statistical Mechanics · Physics 2020-01-22 Michio Tokuyama

In this work, we extend the fractional linear multistep methods in [C. Lubich, SIAM J. Math. Anal., 17 (1986), pp.704--719] to the tempered fractional integral and derivative operators in the sense that the tempered fractional derivative…

Numerical Analysis · Mathematics 2018-12-11 Ling Guo , Fanhai Zeng , Ian Turner , Kevin Burrage , George Em Karniadakis

Mass scaling is widely used in finite element models of structural dynamics for increasing the critical time step of explicit time integration methods. While the field has been flourishing over the years, it still lacks a strong theoretical…

Numerical Analysis · Mathematics 2024-11-14 Yannis Voet , Espen Sande , Annalisa Buffa

In this work, we propose a numerical approach for simulations of large deformations of interfaces in a level set framework. To obtain a fast and viable numerical solution in both time and space, temporal discretization is based on the…

General Mathematics · Mathematics 2023-05-30 Aymen Laadhari , Ahmad Deeb

Approximate solutions of the chemical master equation and the chemical Fokker-Planck equation are an important tool in the analysis of biomolecular reaction networks. Previous studies have highlighted a number of problems with the…

Quantitative Methods · Quantitative Biology 2018-05-22 Leo Bronstein , Heinz Koeppl

We carried out three-dimensional simulations, with about 1.4 million particles, of phase segregation in a low density binary fluid mixture, described mesoscopically by energy and momentum conserving Boltzmann-Vlasov equations. Using a…

patt-sol · Physics 2008-02-03 S. Bastea , J. L. Lebowitz
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