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Collagen fibrils are the most important structural component of tendons. Their crimped structure and parallel arrangement within the tendon lead to a distinctive non-linear stress-strain curve when a tendon is stretched. Microstructural…

Tissues and Organs · Quantitative Biology 2021-03-09 James Gregory , Tom Shearer , Andrew L. Hazel

Type I collagen fibrils have circular cross sections with radii mostly distributed in between 50 and 100 nm and are characterized by an axial banding pattern with a period of 67 nm. The constituent long molecules of those fibrils, the…

Soft Condensed Matter · Physics 2013-10-28 Jean Charvolin , Jean-François Sadoc

In articular cartilage the orientation of collagen fibres is not uniform, varying mostly with the depth on the tissue. Besides, the biomechanical response of each layer of the articular cartilage differs from the neighbouring ones, evolving…

Biological Physics · Physics 2016-01-21 S. Cortez , A. Completo , J. L. Alves

Collagen fibrils, cable-like assemblies of long biological molecules, are dominant components of connective tissues. Their determinant morphological and functional roles motivated a large number of studies concerning their formation and…

Soft Condensed Matter · Physics 2011-04-04 Jean Charvolin , Jean-François Sadoc

Complexity and heterogeneity of bone tissue require a multiscale modelling to understand their mechanical behaviour and their remodelling mechanism. Human cortical bone structure consists of six structural scale levels which are the…

Medical Physics · Physics 2011-12-07 Abdelwahed Barkaoui , Ridha Hambli

The lysyl oxidase (LOX) enzyme that catalyses cross-link formation during the assembly of collagen fibrils in vivo is too large to diffuse within assembled fibrils, and so is incompatible with a fully equilibrium mechanism for fibril…

Biological Physics · Physics 2021-09-30 Matthew P. Leighton , Laurent Kreplak , Andrew D. Rutenberg

Collagen type I is well-known for its outstanding mechanical properties which it inherits from its hierarchical structure. Collagen type I fibrils may be viewed as an heterogeneous material made of protein, macromolecules (such as…

Soft Condensed Matter · Physics 2024-06-27 Maxime Vassaux

The mechanical properties of biological tissues are strongly correlated to the specific distribution of their collagen fibers. Monitoring the dynamic reorganization of the collagen network during mechanical stretching is however a technical…

Type I collagen is the main component of the extra-cellular matrix (ECM). In vitro, under a narrow window of physico-chemical conditions, type I collagen self-assembles to form complex supramolecular architectures reminiscent of those found…

MnN is a centrosymmetric collinear antiferromagnet belonging to the transition metal nitride family with a high Neel temperature, a low anisotropy field, and a large magnetic moment per Mn atom. Despite several recent experimental and…

Materials Science · Physics 2022-06-28 Joongwon Lee , Zexuan Zhang , Huili Xing , Debdeep Jena , Farhan Rana

Collagen is the most abundant structural protein in animals, forming hierarchically organised fibrils that provide mechanical support to tissues. Despite detailed structural studies, the physical principles that govern the formation of the…

Soft Condensed Matter · Physics 2025-05-01 Art'om Zolotarjov , Roland Kröger , Dmitri O. Pushkin

Collagen fibrils are versatile self-assembled structures that provide mechanical integrity within mammalian tissues. The radius of collagen fibrils vary widely depending on experimental conditions \textit{in vitro} or anatomical location…

Soft Condensed Matter · Physics 2018-02-26 Samuel Cameron , Laurent Kreplak , Andrew D. Rutenberg

A new class of micromechanically motivated chain network models for soft biological tissues is presented. On the microlevel, it is based on the statistics of long chain molecules. A wormlike chain model is applied to capture the behavior of…

Quantitative Methods · Quantitative Biology 2009-11-10 E. Kuhl , K. Garikipati , E. M. Arruda , K. Grosh

We present a fiber-distributed model of the reinforcing collagen of the human cornea. The model describes the basic connections between the components of the tissue by defining an elementary block (cell) and upscaling it to the physical…

Biological Physics · Physics 2023-06-28 Maria Laura De Bellis , Marcello Vasta , Alessio Gizzi , Anna Pandolfi

Bone serves as a remarkable example of nature's architectured material with its unique blend of strength and toughness, all at a lightweight design. Given the hierarchical nature of these materials, it is essential to understand the…

Collagen fibrils are the main structural component of load-bearing tissues such as tendons, ligaments, skin, the cornea of the eye, and the heart. The D-band of collagen fibrils is an axial periodic density modulation that can be easily…

Biological Physics · Physics 2021-09-30 Matthew P. Leighton , Andrew D. Rutenberg , Laurent Kreplak

Electromechanical imaging of tooth dentin and enamel has been performed with sub-10 nm resolution using piezoresponse force microscopy. Characteristic piezoelectric domain size and local protein fiber ordering in dentin have been…

Materials Science · Physics 2009-11-11 Sergei V. Kalinin , B. J. Rodriguez , S. Jesse , T. Thundat , A. Gruverman

To describe the interaction between longitudinal density modulations along collagen fibrils (the D-band) with the radial twist-field of molecular orientation (double-twist), we couple phase-field-crystal (PFC) with liquid-crystalline…

Soft Condensed Matter · Physics 2020-03-25 Samuel Cameron , Laurent Kreplak , Andrew D. Rutenberg

A detailed investigation of the structural and vibrational properties of various prestressed silicon nitride membranes patterned with one-dimensional photonic crystal structures is presented. The tensile stress-related deformation of the…

Applied Physics · Physics 2022-05-20 Ali A. Darki , Robin V. Nielsen , Jens V. Nygaard , Aurélien Dantan

A connection between the dynamics of a sine-Gordon chain and a certain static membrane folding problem was recently found. The one-dimensional membrane profile is a cross-section of the position-time sine-Gordon amplitude profile. Here we…

Soft Condensed Matter · Physics 2013-08-20 Haim Diamant , Thomas A. Witten
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