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The reliability of a phylogenetic inference method from genomic sequence data is ensured by its statistical consistency. Bayesian inference methods produce a sample of phylogenetic trees from the posterior distribution given sequence data.…

Metric Geometry · Mathematics 2016-06-10 Alex Gavryushkin , Alexei J. Drummond

When long-lived, balancing selection can lead to trans-species polymorphisms that are shared by two or more species identical by descent. In this case, the gene genealogies at the selected sites cluster by allele instead of by species and,…

Populations and Evolution · Quantitative Biology 2014-01-30 Ziyue Gao , Molly Przeworski , Guy Sella

We prove under mild conditions that the Fleming-Viot process selects the minimal quasi-stationary distribution for Markov processes with soft killing on non-compact state spaces. Our results are applied to multi-dimensional birth and death…

Probability · Mathematics 2018-10-17 Nicolas Champagnat , Denis Villemonais

$\Lambda$-Wright--Fisher processes provide a robust framework to describe the type-frequency evolution of an infinite neutral population. We add a polynomial drift to the corresponding stochastic differential equation to incorporate…

Probability · Mathematics 2023-04-26 Fernando Cordero , Sebastian Hummel , Emmanuel Schertzer

Fixed tree topologies are widely used in phylodynamic analyses to reduce computational burden, yet the consequences of this assumption remain insufficiently understood. Here, we systematically assess the impact of various fixed-topology…

Populations and Evolution · Quantitative Biology 2025-12-01 Mathieu Fourment , Jiansi Gao , Marc A Suchard , Frederick A Matsen

The multi-species coalescent provides an elegant theoretical framework for estimating species trees and species demographics from genetic markers. Practical applications of the multi-species coalescent model are, however, limited by the…

Populations and Evolution · Quantitative Biology 2011-11-09 David Bryant , Remco Bouckaert , Joseph Felsenstein , Noah Rosenberg , Arindam RoyChoudhury

Rooted bifurcating trees are mathematical objects used to model evolutionary relationships and arise naturally in both coalescent theory and phylogenetics. Recent numerical representations of tree topologies, known as F-matrices, allow for…

Kingman's coalescent is a widely used process to model sample genealogies in population genetics. Recently there have been studies on the inference of quantities related to the genealogy of additional individuals given a known sample. This…

Probability · Mathematics 2024-02-29 Linglong Yuan

We consider a strong Markov process with killing and prove an approximation method for the distribution of the process conditioned not to be killed when it is observed. The method is based on a Fleming-Viot type particle system with…

Probability · Mathematics 2013-04-04 Denis Villemonais

The goal of this work is to decompose random populations with a genealogy in subfamilies of a given degree of kinship and to obtain a notion of infinitely divisible genealogies. We model the genealogical structure of a population by…

Probability · Mathematics 2019-04-09 Patrick Gloede , Andreas Greven , Thomas Rippl

Coalescence processes have received a lot of attention in the context of conditional branching processes with fixed population size and non-overlapping generations. Here we focus on similar problems in the context of the standard…

Probability · Mathematics 2017-09-25 Nicolas Grosjean , Thierry Huillet

Bayesian phylogenetics is vital for understanding evolutionary dynamics, and requires accurate and efficient approximation of posterior distributions over trees. In this work, we develop a variational Bayesian approach for ultrametric…

Machine Learning · Statistics 2026-02-16 Evan Sidrow , Alexandre Bouchard-Côté , Lloyd T. Elliott

We investigate a neutral model for speciation and extinction, the constant rate birth-death process. The process is conditioned to have $n$ extant species today, we look at the tree distribution of the reconstructed trees-- i.e. the trees…

Probability · Mathematics 2008-03-04 Tanja Gernhard

Topological phylogenetic trees can be assigned edge weights in several natural ways, highlighting different aspects of the tree. Here the rooted triple and quartet metrizations are introduced, and applied to formulate novel fast methods of…

Populations and Evolution · Quantitative Biology 2019-05-15 John A. Rhodes

We discuss two independent methods of solution of a master equation whose biased jump transition rates account for long jumps of L\'{e}vy-stable type and nonetheless admit a Boltzmannian (thermal) equilibrium to arise in the large time…

Statistical Mechanics · Physics 2015-06-16 Mariusz Żaba , Piotr Garbaczewski , Vladimir Stephanovich

Kingman's coalescent is a random tree that arises from classical population genetic models such as the Moran model. The individuals alive in these models correspond to the leaves in the tree and the following two laws of large numbers…

Probability · Mathematics 2014-06-24 Andrej Depperschmidt , Peter Pfaffelhuber , Annika Scheuringer

We review the statistical properties of the genealogies of a few models of evolution. In the asexual case, selection leads to coalescence times which grow logarithmically with the size of the population in contrast with the linear growth of…

Populations and Evolution · Quantitative Biology 2015-06-04 Éric Brunet , Bernard Derrida

We apply the theory of markov random fields on trees to derive a phase transition in the number of samples needed in order to reconstruct phylogenies. We consider the Cavender-Farris-Neyman model of evolution on trees, where all the inner…

Probability · Mathematics 2007-05-23 Elchanan Mossel

The dynamics of a population undergoing selection is a central topic in evolutionary biology. This question is particularly intriguing in the case where selective forces act in opposing directions at two population scales. For example, a…

Probability · Mathematics 2017-05-03 Shishi Luo , Jonathan C. Mattingly

The goal of this paper is to prove rigorous results for the behavior of genealogies in a one-dimensional long range biased voter model introduced by Hallatschek and Nelson [25]. The first step, which is easily accomplished using results of…

Probability · Mathematics 2021-01-12 Rick Durrett , Wai-Tong Louis Fan