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We propose a theoretical and computational approach to investigate temporal behavior of a nonlinear polarization in perturbative regime induced by an intense and ultrashort pulsed electric field. First-principles time-dependent density…

Optics · Physics 2019-03-27 Mitsuharu Uemoto , Yuki Kuwabara , Shunsuke A. Sato , Kazuhiro Yabana

A key problem of eukaryotic cell motility is the signaling mechanism of chemoattractant gradient sensing. Recent experiments have revealed the molecular correlate of gradient sensing: Frontness molecules, such as PI3P and Rac, localize at…

Cell Behavior · Quantitative Biology 2007-05-23 Atul Narang

Polarization, the precession direction with respect to the background magnetization, is an intrinsic degree of freedom of spin wave. Introducing symmetry breaking mechanisms lies in the heart of lifting the degeneracy between polarized spin…

Mesoscale and Nanoscale Physics · Physics 2022-05-31 Hongbin Wu , Jin Lan

How to induce differentiated cells into pluripotent cells has elicited researchers' interests for a long time since pluripotent stem cells are able to offer remarkable potential in numerous subfields of biological research. However, the…

Molecular Networks · Quantitative Biology 2014-12-09 Jiawei Yan , Pu Zheng , Xingjie Pan

Cells are constantly exposed to fluctuating environmental conditions. External signals are sensed, processed and integrated by cellular signal transduction networks, which translate input signals into specific cellular responses by means of…

Molecular Networks · Quantitative Biology 2012-05-29 Pau Rué , Núria Domedel-Puig , Jordi Garcia-Ojalvo , Antonio J. Pons

Left-right axis specification establishes embryonic laterality through asymmetric signaling cascades originating at the cellular scale. We previously reported the presence of a directionality bias in confined pairs of endothelial (and…

Cell Behavior · Quantitative Biology 2026-03-31 Egun Im , Ghina Badih , Laetitia Kurzawa , Andreas Buttenschön , Calina Copos

Blebs are cell protrusions generated by local membrane-cortex detachments followed by expansion of the plasma membrane. Blebs are formed by some migrating cells, for example primordial germ cells of the zebrafish. While blebs occur randomly…

Analysis of PDEs · Mathematics 2019-12-19 Carolin Dirks , Paul Striewski , Benedikt Wirth , Anne Aalto , Adan Olguin-Olguin , Erez Raz

We analyze order-disorder phase transitions driven by noise that occur in two kinds of network models closely related to the self-propelled model proposed by Vicsek et. al. to describe the collective motion of groups of organisms…

Disordered Systems and Neural Networks · Physics 2008-02-27 Jaime A. Pimentel , Maximino Aldana , Cristián Huepe , Hernán Larralde

In metazoans, cells collectively polarize and align along the tissue plane. This phenomenon is called Planar cell polarity (PCP). Polarization means asymmetric segregation of molecules and sub-cellular structures within a cell. In PCP,…

Adaptation and Self-Organizing Systems · Physics 2023-08-22 Talagadadeevi Nirupamateja , Siva Sai Himakar Sreerangam , Biplab Bose

A biophysical model of epimorphic regeneration based on a continuum percolation process of fully penetrable disks in two dimensions is proposed. All cells within a randomly chosen disk of the regenerating organism are assumed to receive a…

Biological Physics · Physics 2023-11-06 Vladimir García-Morales

We demonstrate that collective vibrational strong coupling of molecules in thermal equilibrium can give rise to significant local electronic polarizations in the thermodynamic limit. We do so by first showing that the full non-relativistic…

Chirally Induced Spin Selectivity (CISS) is a transport phenomenon observed in both linear and non-linear regimes, where the spin-orbit coupling (SOC) acts as the key driver and electron tunneling serves as the dominant mechanism for charge…

Mesoscale and Nanoscale Physics · Physics 2024-01-05 Miguel Mena , Bertrand Berche , Ernesto Medina

Information transmission in biological signaling circuits has often been described using the metaphor of a noise filter. Cellular systems need accurate, real-time data about their environmental conditions, but the biochemical reaction…

Molecular Networks · Quantitative Biology 2019-02-27 David Hathcock , James Sheehy , Casey Weisenberger , Efe Ilker , Michael Hinczewski

Wave-particle duality is certainly one of the most curious concepts of contemporary physics, which ascribes mutually exclusive behaviors to quantum systems that cannot be observed simultaneously. In the context of two-path interferometers,…

The dynamic patterning of the plant hormone auxin and its efflux facilitator the PIN protein are the key regulator for the spatial and temporal organization of plant development. In particular auxin induces the polar localization of its own…

Tissues and Organs · Quantitative Biology 2013-02-06 Karen Alim , Erwin Frey

Protrusions at the leading-edge of a cell play an important role in sensing the extracellular cues, during cellular spreading and motility. Recent studies provided indications that these protrusions wrap (coil) around the extra-cellular…

Polarization arises when the underlying network connecting the members of a community or society becomes characterized by highly connected groups with weak inter-group connectivity. The increasing polarization, the strengthening of echo…

Social and Information Networks · Computer Science 2023-04-06 Ruben Interian , Ruslan G. Marzo , Isela Mendoza , Celso C. Ribeiro

Planar cell polarity (PCP), the coherent in-plane polarization of a tissue on multicellular length scales, provides directional information that guides a multitude of developmental processes at cellular and tissue levels. While it is…

Biological Physics · Physics 2020-07-01 Shahriar Shadkhoo , Madhav Mani

Due to inherent noise in intracellular networks cellular decisions can be random, so genetically identical cells can display different phenotypic behavior even in identical environments. Most previous work in understanding the…

Molecular Networks · Quantitative Biology 2015-06-15 Michael Assaf , Elijah Roberts , Zaida Luthey-Schulten , Nigel Goldenfeld

Cellular signaling involves the transmission of environmental information through cascades of stochastic biochemical reactions, inevitably introducing noise that compromises signal fidelity. Each stage of the cascade often takes the form of…

Molecular Networks · Quantitative Biology 2014-08-20 Michael Hinczewski , D. Thirumalai