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Coordinating multi-articulated bodies to generate purposeful movement is a formidable computational challenge. Yet the human motor system performs this task robustly in dynamic, uncertain environments, despite noisy and delayed feedback,…

Neurons and Cognition · Quantitative Biology 2026-02-24 Alessandro Salatiello

In order to find the equilibrium geometries of molecules and solids and to perform ab initio molecular dynamics, it is necessary to calculate the forces on the nuclei. We present a correlated sampling method to efficiently calculate…

Condensed Matter · Physics 2009-10-31 Claudia Filippi , C. J. Umrigar

Neuronal networks in dissociated culture combined with cell engineering technology offer a pivotal platform to constructively explore the relationship between structure and function in living neuronal networks. Here, we fabricated defined…

Neurons and Cognition · Quantitative Biology 2023-01-11 Yuya Sato , Hideaki Yamamoto , Hideyuki Kato , Takashi Tanii , Shigeo Sato , Ayumi Hirano-Iwata

Neurons in the brain represent external stimuli via neural codes. These codes often arise from stereotyped stimulus-response maps, associating to each neuron a convex receptive field. An important problem confronted by the brain is to infer…

Neurons and Cognition · Quantitative Biology 2015-02-25 Carina Curto , Vladimir Itskov , Alan Veliz-Cuba , Nora Youngs

We consider dense, associative neural-networks trained with no supervision and we investigate their computational capabilities analytically, via a statistical-mechanics approach, and numerically, via Monte Carlo simulations. In particular,…

Disordered Systems and Neural Networks · Physics 2023-07-04 Elena Agliari , Linda Albanese , Francesco Alemanno , Andrea Alessandrelli , Adriano Barra , Fosca Giannotti , Daniele Lotito , Dino Pedreschi

We introduce a model for an artificial neuron which is based on ballistic transport in a multi-terminal device. Unlike standard configurations, the proposed design embeds the synaptic weights into the active region, thus significantly…

Applied Physics · Physics 2019-12-21 George Alexandru Nemnes , Daniela Dragoman

This paper introduces the Modular Neural Computer (MNC), a memory-augmented neural architecture for exact algorithmic computation on variable-length inputs. The model combines an external associative memory of scalar cells, explicit read…

Machine Learning · Computer Science 2026-03-17 Florin Leon

Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Guillermo A. Cecchi , Marcelo O. Magnasco

Electric circuits manipulate electric charge and magnetic flux via a small set of discrete components to implement useful functionality over continuous time-varying signals represented by currents and voltages. Much of the same…

Systems and Control · Computer Science 2018-12-11 Luca Cardelli , Mirco Tribastone , Max Tschaikowski

Improvements in technique in conjunction with an evolution of the theoretical and conceptual approach to neuronal networks provide a new perspective on living neurons in culture. Organization and connectivity are being measured…

Disordered Systems and Neural Networks · Physics 2010-08-02 Jean-Pierre Eckmann , Ofer Feinerman , Leor Gruendlinger , Elisha Moses , Jordi Soriano , Tsvi Tlusty

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes

We perform Monte Carlo simulations to study the elastic properties of the helix-coil worm-like chain model of alpha-helical polypeptides. In this model the secondary structure enters as a scalar (Ising like) variable that controls the local…

Soft Condensed Matter · Physics 2007-05-23 Buddhapriya Chakrabarti , Alex J. Levine

Neural codes are collections of binary strings motivated by patterns of neural activity. In this paper, we study algorithmic and enumerative aspects of convex neural codes in dimension 1 (i.e. on a line or a circle). We use the theory of…

Combinatorics · Mathematics 2017-02-23 Zvi Rosen , Yan X. Zhang

Although lagging behind classical computational neuroscience, theoretical and computational approaches are beginning to emerge to characterize different aspects of neuron-glial interactions. This chapter aims to provide essential knowledge…

Neurons and Cognition · Quantitative Biology 2021-03-10 Maurizio De Pittà

The neural coding is yet to be discovered. The neuronal operational modes that arise with fixed inputs but with varying degrees of stimulation help to elucidate their coding properties. In neurons receiving {\it in vivo} stimulation, we…

Neurons and Cognition · Quantitative Biology 2025-11-05 Lindsey Knowles , Cesar Ceballos , Rodrigo Pena

Neuromorphic computing seeks to replicate the spiking dynamics of biological neurons for brain-inspired computation. While electronic implementations of artificial spiking neurons have dominated to date, photonic approaches are attracting…

We present novel Monte Carlo methods for treating the interacting shell model that allow exact calculations much larger than those heretofore possible. The two-body interaction is linearized by an auxiliary field; Monte Carlo evaluation of…

Nuclear Theory · Physics 2008-11-26 C. W. Johnson , S. E. Koonin , G. H. Lang , W. E. Ormand

Neural Module Networks, originally proposed for the task of visual question answering, are a class of neural network architectures that involve human-specified neural modules, each designed for a specific form of reasoning. In current…

Machine Learning · Computer Science 2019-11-11 Vardaan Pahuja , Jie Fu , Sarath Chandar , Christopher J. Pal

Molecular communication is a biologically-inspired method of communication with attractive properties for microscale and nanoscale devices. In molecular communication, messages are transmitted by releasing a pattern of molecules at a…

Information Theory · Computer Science 2008-12-09 Andrew W. Eckford

To evaluate the nature of the neural code in the cerebral cortex, we have used a combination of theory and experiment to assess how information is represented in a realistic cortical population response. We have shown how a sensory stimulus…

Neurons and Cognition · Quantitative Biology 2008-03-28 L. C. Osborne , S. E. Palmer , S. G. Lisberger , W. Bialek
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