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The hypercube queueing model was initially developed to address spatial queueing problems and has found wide applications in emergency services, such as ambulance and police systems. While the model was originally designed for homogeneous…

Optimization and Control · Mathematics 2026-03-10 Cheng Hua , Jun Luo , Arthur J. Swersey , Yixing Wen

Stochastic modeling of reaction networks is a framework used to describe the time evolution of many natural and artificial systems, including, biochemical reactive systems at the molecular level, viral kinetics, the spread of epidemic…

Numerical Analysis · Mathematics 2014-06-10 Alvaro Moraes , Raul Tempone , Pedro Vilanova

We present a new blocking linearizable stack implementation which utilizes sharding and fetch&increment to achieve significantly better performance than all existing concurrent stacks. The proposed implementation is based on a novel…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-09 Ajay Singh , Nikos Metaxakis , Panagiota Fatourou

Artificial intelligence (AI) application domains consist of a mix of tensor operations with high and low arithmetic intensities (aka reuse). Hierarchical (i.e. compute along multiple levels of memory hierarchy) and heterogeneous (multiple…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-19 Raveesh Garg , Michael Pellauer , Tushar Krishna

Actor-Critic models are a class of model-free deep reinforcement learning (RL) algorithms that have demonstrated effectiveness across various robot learning tasks. While considerable research has focused on improving training stability and…

Robotics · Computer Science 2025-10-01 Hanlan Yang , Itamar Mishani , Luca Pivetti , Zachary Kingston , Maxim Likhachev

Stochasticity plays a fundamental role in various biochemical processes, such as cell regulatory networks and enzyme cascades. Isothermal, well-mixed systems can be modelled as Markov processes, typically simulated using the Gillespie…

Molecular Networks · Quantitative Biology 2016-10-12 Andrew Duncan , Radek Erban , Konstantinos Zygalakis

In recent years, robots and autonomous systems have become increasingly integral to our daily lives, offering solutions to complex problems across various domains. Their application in search and rescue (SAR) operations, however, presents…

Robotics · Computer Science 2024-09-23 Dimitrios Panagopoulos , Adolfo Perrusquia , Weisi Guo

The analysis of data from multiple experiments, such as observations of several individuals, is commonly approached using mixed-effects models, which account for variation between individuals through hierarchical representations. This makes…

Computation · Statistics 2026-03-05 Henrik Häggström , Sebastian Persson , Marija Cvijovic , Umberto Picchini

This paper discusses new simulation algorithms for stochastic chemical kinetics that exploit the linearity of the chemical master equation and its matrix exponential exact solution. These algorithms make use of various approximations of the…

Numerical Analysis · Computer Science 2016-09-08 Azam S. Zavar Moosavi , Adrian Sandu

Computational chemistry has become an important tool to predict and understand molecular properties and reactions. Even though recent years have seen a significant growth in new algorithms and computational methods that speed up quantum…

Chemical Physics · Physics 2023-07-26 Albert Thie , Maximilian F. S. J. Menger , Shirin Faraji

Deploying deep neural networks for risk-sensitive tasks necessitates an uncertainty estimation mechanism. This paper introduces hierarchical selective classification, extending selective classification to a hierarchical setting. Our…

Machine Learning · Computer Science 2025-01-07 Shani Goren , Ido Galil , Ran El-Yaniv

Recent advancements in reinforcement learning have made significant impacts across various domains, yet they often struggle in complex multi-agent environments due to issues like algorithm instability, low sampling efficiency, and the…

Multiagent Systems · Computer Science 2024-08-22 Cheng Xu , Changtian Zhang , Yuchen Shi , Ran Wang , Shihong Duan , Yadong Wan , Xiaotong Zhang

Synthetic lethal reaction/gene-sets are sets of reactions/genes where only the simultaneous removal of all reactions/genes in the set abolishes growth of an organism. In silico, synthetic lethal sets can be identified by simulating the…

Molecular Networks · Quantitative Biology 2015-07-02 Aditya Pratapa , Shankar Balachandran , Karthik Raman

We propose a hierarchy of multi-level kinetic Monte Carlo methods for sampling high-dimensional, stochastic lattice particle dynamics with complex interactions. The method is based on the efficient coupling of different spatial resolution…

Numerical Analysis · Mathematics 2012-08-06 Evangelia Kalligiannaki , Markos A. Katsoulakis , Petr Plechac

Numerous algorithms and parallelisations have been developed for short-range particle simulations; however, none are optimally performant for all scenarios. Such a concept led to the prior development of the particle simulation library…

Computational Engineering, Finance, and Science · Computer Science 2025-05-07 Samuel James Newcome , Fabio Alexander Gratl , Manuel Lerchner , Abdulkadir Pazar , Manish Kumar Mishra , Hans-Joachim Bungartz

AB testing aids business operators with their decision making, and is considered the gold standard method for learning from data to improve digital user experiences. However, there is usually a gap between the requirements of practitioners,…

Machine Learning · Computer Science 2023-07-28 Srivas Chennu , Andrew Maher , Christian Pangerl , Subash Prabanantham , Jae Hyeon Bae , Jamie Martin , Bud Goswami

An effective implementation of enhanced sampling algorithms for molecular dynamics simulations requires a priori knowledge of the approximate reaction coordinate describing the relevant mechanisms in the system. Here we demonstrate how the…

Biological Physics · Physics 2021-12-22 Shams Mehdi , Dedi Wang , Shashank Pant , Pratyush Tiwary

The combination of spiking neural networks and event-based vision sensors holds the potential of highly efficient and high-bandwidth optical flow estimation. This paper presents the first hierarchical spiking architecture in which motion…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Federico Paredes-Vallés , Kirk Y. W. Scheper , Guido C. H. E. de Croon

This paper considers a class of reinforcement learning problems, which involve systems with two types of states: stochastic and pseudo-stochastic. In such systems, stochastic states follow a stochastic transition kernel while the…

Machine Learning · Computer Science 2023-11-09 Honghao Wei , Xin Liu , Weina Wang , Lei Ying

Image Retrieval is commonly evaluated with Average Precision (AP) or Recall@k. Yet, those metrics, are limited to binary labels and do not take into account errors' severity. This paper introduces a new hierarchical AP training method for…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Elias Ramzi , Nicolas Audebert , Nicolas Thome , Clément Rambour , Xavier Bitot