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Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the second of a…

Medical Physics · Physics 2018-09-14 Delbary Fabrice , Garbarino Sara

Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the first of a…

Quantitative Methods · Quantitative Biology 2018-08-21 Fabrice Delbary , Sara Garbarino , Valentina Vivaldi

The renal vasculature, acting as a resource distribution network, plays an important role in both the physiology and pathophysiology of the kidney. However, no imaging techniques allow an assessment of the structure and function of the…

Computational Engineering, Finance, and Science · Computer Science 2023-05-11 Peidi Xu , Niels-Henrik Holstein-Rathlou , Stinne Byrholdt Søgaard , Carsten Gundlach , Charlotte Mehlin Sørensen , Kenny Erleben , Olga Sosnovtseva , Sune Darkner

This paper utilizes compartmental analysis and a statistical optimization technique in order to reduce a compartmental model describing the metabolism of labelled glucose in liver. Specifically, we first design a compartmental model for the…

Tissues and Organs · Quantitative Biology 2013-06-03 Valentina Vivaldi , Sara Garbarino , Giacomo Caviglia , Michele Piana , Gianmario Sanbuceti

Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…

Tissues and Organs · Quantitative Biology 2020-01-22 Michele Piana , Giacomo Caviglia , Sara Sommariva

This review article provides an overview of structurally oriented experimental datasets that can be used to benchmark protein force fields, focusing on data generated by nuclear magnetic resonance (NMR) spectroscopy and room temperature…

Conformational dynamics is crucial for ribonucleic acid (RNA) function. Techniques such as nuclear magnetic resonance, cryo-electron microscopy, small- and wide-angle X-ray scattering, chemical probing, single-molecule F\"orster resonance…

Biomolecules · Quantitative Biology 2025-01-31 Mattia Bernetti , Giovanni Bussi

We present some results and remarks based on a combinatorial approach of the evaluation of the nuclear level density. First, we show that it is possible to extract some reliable information from the output of the program whose rough data…

Nuclear Theory · Physics 2007-05-23 Bernard PICHON CNRS

In this paper, we present a diagnosis method of diseases from clinical data. The data are routine test such as urine test, hematology, chemistries etc. Though those tests have been done for people who check in medical institutes, how each…

Computational Engineering, Finance, and Science · Computer Science 2007-05-23 Gene Kim , MyungHo Kim

We propose generalized additive partial linear models for complex data which allow one to capture nonlinear patterns of some covariates, in the presence of linear components. The proposed method improves estimation efficiency and increases…

Statistics Theory · Mathematics 2014-05-26 Li Wang , Lan Xue , Annie Qu , Hua Liang

Statistical modeling of data sets by neural-network techniques is offered as an alternative to traditional semiempirical approaches to global modeling of nuclear properties. New results are presented to support the position that such novel…

Nuclear Theory · Physics 2017-08-23 J. W. Clark , E. Mavrommatis , S. Athanassopoulos , A. Dakos , K. Gernoth

Computational pathology is a field that has complemented various subspecialties of diagnostic pathology over the last few years. In this article a brief analyzis the different applications in nephrology is developed. To begin, an overview…

Image and Video Processing · Electrical Eng. & Systems 2022-10-20 Manuel Cossio

We present an overview of concepts and results obtained with statistical models in study of nuclear multifragmentation. Conceptual differences between statistical and dynamical approaches, and selection of experimental observables for…

Nuclear Theory · Physics 2009-11-11 A. S. Botvina , I. N. Mishustin

Existing statistical methods for the analysis of micro-randomized trials (MRTs) are designed to estimate causal excursion effects using data from a single MRT. In practice, however, researchers can often find previous MRTs that employ…

Methodology · Statistics 2025-05-13 Easton Huch , Inbal Nahum-Shani , Lindsey Potter , Cho Lam , David W. Wetter , Walter Dempsey

The analysis of human microbiome data is often based on dimension-reduced graphical displays and clustering derived from vectors of microbial abundances in each sample. Common to these ordination methods is the use of biologically motivated…

Applications · Statistics 2017-01-11 Timothy W. Randolph , Sen Zhao , Wade Copeland , Meredith Hullar , Ali Shojaie

It is possible to approach regression analysis with random covariates from a semiparametric perspective where information is combined from multiple multivariate sources. The approach assumes a semiparametric density ratio model where…

Methodology · Statistics 2012-10-02 Anastasia Voulgaraki , Benjamin Kedem , Barry I. Graubard

Partial nephrectomy (PN) is common surgery in urology. Digitization of renal anatomies brings much help to many computer-aided diagnosis (CAD) techniques during PN. However, the manual delineation of kidney vascular system and tumor on each…

Image and Video Processing · Electrical Eng. & Systems 2023-05-24 Nan Ma , Ying Yang , Dongkai Zhou

We present a detailed physiological model of the retina that includes the biochemistry and electrophysiology of phototransduction, neuronal electrical coupling, and the spherical geometry of the eye. The model is a parabolic-elliptic system…

Quantitative Methods · Quantitative Biology 2023-03-09 Belal Abuelnasr , Adam R. Stinchcombe

Using a statistical model-based data generation, we develop an experimental setup for the evaluation of neural networks (NNs). The setup helps to benchmark a set of NNs vis-a-vis minimum-mean-square-error (MMSE) performance bounds. This…

Machine Learning · Computer Science 2020-11-19 Sandipan Das , Prakash B. Gohain , Alireza M. Javid , Yonina C. Eldar , Saikat Chatterjee

Statistical models for describing the probability distribution over the states of biological systems are commonly used for dimensional reduction. Among these models, pairwise models are very attractive in part because they can be fit using…

Quantitative Methods · Quantitative Biology 2009-11-30 Yasser Roudi , Erik Aurell , John Hertz
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