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A tumor can be thought of as an ecosystem, which critically means that we cannot just consider it as a collection of mutated cells but more as a complex system of many interacting cellular and microenvironmental elements. At its simplest, a…

Populations and Evolution · Quantitative Biology 2013-05-03 Jill Gallaher , Alexander R. A. Anderson

Given any regularly varying dislocation measure, we identify a natural self-similar fragmentation tree as scaling limit of discrete fragmentation trees with unit edge lengths. As an application, we obtain continuum random tree limits of…

Probability · Mathematics 2009-09-29 Bénédicte Haas , Grégory Miermont , Jim Pitman , Matthias Winkel

The random first-order transition (RFOT) theory of the structural glass transition is reviewed in a pedagogical fashion. The rigidity that emerges in crystals and glassy liquids is of the same fundamental origin. In both cases, it…

Disordered Systems and Neural Networks · Physics 2015-11-20 Vassiliy Lubchenko

We show that in small and low density systems described by a lattice gas model with fixed number of particles the location of a thermodynamic phase transition can be detected by means of the distribution of the fluctuations related to an…

Nuclear Theory · Physics 2009-11-07 J. M. Carmona , J. Richert , P. Wagner

We study anomalous transport arising in disordered one-dimensional spin chains, specifically focusing on the subdiffusive transport typically found in a phase preceding the many-body localization transition. Different types of transport can…

Disordered Systems and Neural Networks · Physics 2020-03-09 Maximilian Schulz , Scott R. Taylor , Antonello Scardicchio , Marko Žnidarič

We provide here a brief perspective on the glass transition field. It is an assessment, written from the point of view of theory, of where the field is and where it seems to be heading. We first give an overview of the main phenomenological…

Statistical Mechanics · Physics 2015-06-15 Giulio Biroli , Juan P. Garrahan

{\bf Purpose}: To develop a geometry-governed diffusion framework that explains differential tissue response under FLASH ultra-high dose rate (UHDR) irradiation by explicitly accounting for structural heterogeneity and anomalous transport…

Medical Physics · Physics 2026-04-20 Neda Valizadeh , Robabeh Rahimi , Ramin Abolfath

Modelling the substitution of nucleotides along a phylogenetic tree is usually done by a hidden Markov process. This allows to define a distribution of characters at the leaves of the trees and one might be able to obtain polynomial…

Populations and Evolution · Quantitative Biology 2020-10-12 Marta Casanellas , Jesús Fernández-Sánchez , Marina Garrote-López

Our goal is to visualize an additional data dimension of a tree with multifaceted data through superimposition on vertical strips, which we call columns. Specifically, we extend upward drawings of unordered rooted trees where vertices have…

Computational Geometry · Computer Science 2023-09-06 Jonathan Klawitter , Johannes Zink

Phylogenomics heavily relies on well-curated sequence data sets that consist, for each gene, exclusively of 1:1-orthologous. Paralogs are treated as a dangerous nuisance that has to be detected and removed. We show here that this severe…

Discrete Mathematics · Computer Science 2017-12-19 Marc Hellmuth , Nicolas Wieseke , Marcus Lechner , Hans-Peter Lenhof , Martin Middendorf , Peter F. Stadler

Morphoelasticity represents a foundational theory for tracing back growth, remodelling, and morphogenesis, yet crucial challenges persist. A unified growth law -- independent of a priori assumptions about constitutive relations or specified…

Soft Condensed Matter · Physics 2025-07-29 Angelo Rosario Carotenuto , Stefania Palumbo , Arsenio Cutolo , Massimiliano Fraldi

Grain growth in polycrystals is traditionally considered a capillarity-driven process, where grain boundaries (GBs) migrate toward their centers of curvature (i.e., mean curvature flow) with a velocity proportional to the local curvature…

Materials Science · Physics 2025-09-12 Caihao Qiu , David J. Srolovitz , Gregory S. Rohrer , Jian Han , Marco Salvalaglio

Recently, fractional derivatives have been employed to analyze various systems in engineering, physics, finance and hidrology. For instance, they have been used to investigate anomalous diffusion processes which are present in different…

Soft Condensed Matter · Physics 2023-11-28 Kwok Sau Fa , E. K. Lenzi

We analyze the temporal fluctuations of the flow field associated to a shear-induced transition in a lyotropic lamellar phase: the layering transition of the onion texture. In the first part of this work [Salmon et al., submitted to Phys.…

Soft Condensed Matter · Physics 2009-11-10 J-. B. Salmon , S. Manneville , A. Colin

A central goal of protein-folding theory is to predict the stochastic dynamics of transition paths --- the rare trajectories that transit between the folded and unfolded ensembles --- using only thermodynamic information, such as a…

Biomolecules · Quantitative Biology 2018-08-09 William M. Jacobs , Eugene I. Shakhnovich

We give a complete criterion for when two hyperbolic automorphisms of a tree generate a free, discrete subgroup. The decision depends only on three geometric invariants: the translation lengths of the generators and the length of overlap of…

Group Theory · Mathematics 2025-12-02 Yukun Du , Sa'ar Hersonsky

Cellular differentiation and evolution are stochastic processes that can involve multiple types (or states) of particles moving on a complex, high-dimensional state-space or "fitness" landscape. Cells of each specific type can thus be…

Populations and Evolution · Quantitative Biology 2014-11-17 Tom Chou , Yu Wang

A liquid droplet is fragmented by a sudden pressurized-gas blow, and the resulting droplets, adhered to the window of a flatbed scanner, are counted and sized by computerized means. The use of a scanner plus image recognition software…

Statistical Mechanics · Physics 2009-11-13 Cristian F. Moukarzel , Silvia F. Fernandez-Sabido , J. C. Ruiz-Suarez

Transformations accompanying shape-instability govern the morphological configuration and distribution of the phases in a microstructure. Owing to the influence of the microstructure on the properties of a material, the stability of…

Computational Engineering, Finance, and Science · Computer Science 2020-06-17 Tobias Mittnacht , Prince Gideon Kubendran Amos , Daniel Schneider , Britta Nestler

The properties of a front between two different phases in the presence of a smoothly inhomogeneous external field that takes its critical value at the crossing point is analyzed. Two generic scenarios are studied. In the first, the system…

Pattern Formation and Solitons · Physics 2015-08-17 Haim Weissmann , Nadav M. Shnerb , David A. Kessler
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