Related papers: Optimal diagnostic tests for sporadic Creutzfeldt-…
Introduction Sporadic Creutzfeldt Jakob disease sCJD is a rapidly progressive neurodegenerative disease without effective treatment that usually results in death within one year. The recently applied methods have improved the accuracy of…
BACKGROUND: Randomized controlled trials (RCTs) are the gold standard design of clinical research to assess interventions. However, RCTs cannot always be applied for practical or ethical reasons. To investigate the current practices in rare…
Creutzfeldt-Jakob disease (CJD) is a rapidly progressive and fatal neurodegenerative disease, that causes approximately 350 deaths in the United States every year. In specific, it is a prion disease that is caused by a misfolded prion…
Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet…
Machine Learning is an important sub-field of the Artificial Intelligence and it has been become a very critical task to train Machine Learning techniques via effective method or techniques. Recently, researchers try to use alternative…
We treat the statistical inference problems in which one needs to detect and estimate simultaneously using as small number of samples as possible. Conventional methods treat the detection and estimation subproblems separately, ignoring the…
In this study; in order to diagnose congestive heart failure (CHF) patients, non-linear second-order difference plot (SODP) obtained from raw 256 Hz sampled frequency and windowed record with different time of ECG records are used. All of…
In medical diagnosis, physicians predict the state of a patient by checking measurements (features) obtained from a sequence of tests, e.g., blood test, urine test, followed by invasive tests. As tests are often costly, one would like to…
Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…
The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…
Machine learning models have been successfully employed in the diagnosis of Schizophrenia disease. The impact of classification models and the feature selection techniques on the diagnosis of Schizophrenia have not been evaluated. Here, we…
In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…
Computer based recognition and detection of abnormalities in ECG signals is proposed. For this purpose, the Support Vector Machines (SVM) are combined with the advantages of Hermite transform representation. SVM represent a special type of…
Support Vector Data Description (SVDD) is a popular one-class classifiers for anomaly and novelty detection. But despite its effectiveness, SVDD does not scale well with data size. To avoid prohibitive training times, sampling methods…
Automatic diagnosis of coronary heart disease helps the doctor to support in decision making a diagnosis. Coronary heart disease have some types or levels. Referring to the UCI Repository dataset, it divided into 4 types or levels that are…
Protein folding is a problem of large interest since it concerns the mechanism by which the genetic information is translated into proteins with well defined three-dimensional (3D) structures and functions. Recently theoretical models have…
Diabetes is a major health problem in both developing and developed countries and its incidence is rising dramatically. In this study, we investigate a novel automatic approach to diagnose Diabetes disease based on Feature Weighted Support…
In machine learning one often assumes the data are independent when evaluating model performance. However, this rarely holds in practise. Geographic information data sets are an example where the data points have stronger dependencies among…
Cardiovascular disease (CVD) persists as a primary cause of death on a global scale, which requires more effective and timely detection methods. Traditional supervised learning approaches for CVD detection rely heavily on large-labeled…
Sensitivity and specificity evaluated at an optimal diagnostic cut-off are fundamental measures of classification accuracy when continuous biomarkers are used for disease diagnosis. Joint inference for these quantities is challenging…