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Assessing the synergistic high-order behaviors (HOBs) that emerge from underlying structural mechanisms is crucial to characterize complex systems. This work leverages the combined use of predictability and information measures to detect…

Quantitative Methods · Quantitative Biology 2025-12-16 Chiara Barà , Yuri Antonacci , Laura Sparacino , Helder Pinto , Michal Javorka , Sebastiano Stramaglia , Luca Faes

A statistical inference method is developed and tested for pairwise interacting systems whose degrees of freedom are continuous angular variables, such as planar spins in magnetic systems or wave phases in optics and acoustics. We…

Statistical Mechanics · Physics 2015-06-15 P. Tyagi , A. Pagnani , F. Antenucci , M. Ibáñez Berganza , L. Leuzzi

Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…

Quantitative Methods · Quantitative Biology 2025-09-05 Andrew J. Stier , Naichen Shi , Raed Al Kontar , Chad Giusti , Marc G. Berman

Information-theoretic quantities reveal dependencies among variables in the structure of joint, marginal, and conditional entropies, but leave some fundamentally different systems indistinguishable. Furthermore, there is no consensus on how…

Information Theory · Computer Science 2023-05-09 Abel Jansma

A statistically principled way of conducting weighted network analysis is still lacking. Comparison of different populations of weighted networks is hard because topology is inherently dependent on wiring cost, where cost is defined as the…

Molecular Networks · Quantitative Biology 2015-05-27 Cedric E. Ginestet , Thomas E. Nichols , Ed T. Bullmore , Andrew Simmons

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

Neurons and Cognition · Quantitative Biology 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

This study addresses the challenge of accurately identifying multi-task contention types in high-dimensional system environments and proposes a unified contention classification framework that integrates representation transformation,…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-29 Xiao Yang , Yinan Ni , Yuqi Tang , Zhimin Qiu , Chen Wang , Tingzhou Yuan

Topological data analyses are rapidly turning into key tools for quantifying large volumes of neurobiological data, e.g., for organizing the spiking outputs of large neuronal ensembles and thus gaining insights into the information produced…

Neurons and Cognition · Quantitative Biology 2019-09-18 Yuri Dabaghian

Techniques from computational topology, in particular persistent homology, are becoming increasingly relevant for data analysis. Their stable metrics permit the use of many distance-based data analysis methods, such as multidimensional…

Algebraic Topology · Mathematics 2021-01-20 Bastian Rieck , Filip Sadlo , Heike Leitte

Networks are frequently used to model complex systems comprised of interacting elements. While edges capture the topology of direct interactions, the true complexity of many systems originates from higher-order patterns in paths by which…

Social and Information Networks · Computer Science 2022-10-04 Christoph Gote , Vincenzo Perri , Ingo Scholtes

Principles of network topology have been widely studied in the human connectome. Of particular interest is the modularity of the human brain, where the connectome is divided into subnetworks and subsequently changes with development, aging…

Neurons and Cognition · Quantitative Biology 2019-02-05 Markus D. Schirmer , Ai Wern Chung , P. Ellen Grant , Natalia S. Rost

Topological learning is a wide research area aiming at uncovering the mutual spatial relationships between the elements of a set. Some of the most common and oldest approaches involve the use of unsupervised competitive neural networks.…

Machine Learning · Statistics 2021-11-03 Pietro Barbiero , Gabriele Ciravegna , Vincenzo Randazzo , Giansalvo Cirrincione

Couplings in complex real-world systems are often nonlinear and scale-dependent. In many cases, it is crucial to consider a multitude of interlinked variables and the strengths of their correlations to adequately fathom the dynamics of a…

Data Analysis, Statistics and Probability · Physics 2022-10-26 Tobias Braun , K. Hauke Kraemer , Norbert Marwan

The inference of an underlying network topology from local observations of a complex system composed of interacting units is usually attempted by using statistical similarity measures, such as Cross-Correlation (CC) and Mutual Information…

Data Analysis, Statistics and Probability · Physics 2014-09-03 Nicolás Rubido , Arturo C. Martí , Ezequiel Bianco-Martínez , Celso Grebogi , Murilo S. Baptista , Cristina Masoller

Persistent homology is a popular and powerful tool for capturing topological features of data. Advances in algorithms for computing persistent homology have reduced the computation time drastically -- as long as the algorithm does not…

Computational Geometry · Computer Science 2013-10-03 Ulrich Bauer , Michael Kerber , Jan Reininghaus

The statistical analysis of marked point processes requires disentangling complex spatial arrangements from attribute-dependent interactions. While classical summary statistics are effective for second-order dependencies, they frequently…

Methodology · Statistics 2026-05-15 Matthias Eckardt , Mehdi Moradi

In data clustering, it is often desirable to find not just a single partition into clusters but a sequence of partitions that describes the data at different scales (or levels of coarseness). A natural problem then is to analyse and compare…

Algebraic Topology · Mathematics 2025-04-25 Juni Schindler , Mauricio Barahona

Networks are a fundamental model of complex systems throughout the sciences, and network datasets are typically analyzed through lower-order connectivity patterns described at the level of individual nodes and edges. However, higher-order…

Social and Information Networks · Computer Science 2018-02-21 Austin R. Benson

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

Testing two potentially multivariate variables for statistical dependence on the basis finite samples is a fundamental statistical challenge. Here we explore a family of tests that adapt to the complexity of the relationship between the…

Machine Learning · Statistics 2020-10-23 Baihan Lin , Nikolaus Kriegeskorte