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We investigate the relationship between the blood flow velocities (BFV) in the middle cerebral arteries and beat-to-beat blood pressure (BP) recorded from a finger in healthy and post-stroke subjects during the quasi-steady state after…

Biological Physics · Physics 2007-05-23 Zhi Chen , Kun Hu , H. Eugene Stanley , Vera Novak , Plamen Ch. Ivanov

Nonequilibrium dynamics of biomembranes with active inclusions is considered. The inclusions represent protein molecules which perform cyclic internal conformational motions driven by the energy brought with ATP ligands. As protein…

Soft Condensed Matter · Physics 2015-05-13 Hsuan-Yi Chen , Alexander S. Mikhailov

Atherosclerosis is characterised by the growth of fatty plaques in the inner (intimal) layer of the artery wall. In mature plaques, vascular smooth muscle cells (SMCs) are recruited from the adjacent medial layer to deposit a cap of fibrous…

Cell Behavior · Quantitative Biology 2019-08-09 Michael G. Watson , Helen M. Byrne , Charlie Macaskill , Mary R. Myerscough

Polymerization dynamics of single actin filaments is investigated theoretically using a stochastic model that takes into account the hydrolysis of ATP-actin subunits, the geometry of actin filament tips, the lateral interactions between the…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

In contrast to equilibrium systems, inertia can profoundly impact the phase behavior of active systems. This has been made particularly evident in recent years, with motility-induced phase separation (MIPS) exhibiting several intriguing…

Soft Condensed Matter · Physics 2025-04-21 Jiechao Feng , Ahmad K. Omar

Recently, some of us developed a novel model glass-forming liquid with k extra interactions with pseudo neighbours to each liquid particle over and above the regular interactions with its neighbours. Analysis of the structure and dynamics…

Protein assembly plays an important role in the regulation of biological systems. The cytoskeleton assembly activity is provided by the binding cofactors GTP (guanidine triphosphate) or ATP(adenosine triphosphate) to monomeric protein, and…

Subcellular Processes · Quantitative Biology 2015-10-13 Tatsuaki Tsuruyama

The steady-state nucleation rate and flux of composite nucleus at the saddle point is studied by extending the theory of binary nucleation. The Fokker-Planck equation that describes the nucleation flux is derived using the Master equation…

Materials Science · Physics 2015-06-05 Masao Iwamatsu

We present a mode-coupling theory (MCT) for the high-density dynamics of two-dimensional spherical active Brownian particles (ABP). The theory is based on the integration-through-transients (ITT) formalism and hence provides a starting…

Soft Condensed Matter · Physics 2017-12-20 Alexander Liluashvili , Jonathan Onody , Thomas Voigtmann

Fluctuating entropy production is studied for a set of linearly coupled complex fields. The general result is applied to non-equilibrium fluctuating hydrodynamic equations for coarse-grained fields (density, temperature and velocity), in…

Statistical Mechanics · Physics 2012-07-09 Giacomo Gradenigo , Andrea Puglisi , Alessandro Sarracino

A run-and-tumble particle in a one dimensional box (infinite potential well) is studied. The steady state is analytically solved and analyzed, revealing the emergent length scale of the boundary layer where particles accumulate near the…

Statistical Mechanics · Physics 2020-10-07 Nitzan Razin

Confocal time resolved single-molecule spectroscopy using pulsed laser excitation and synchronized multi channel time correlated single photon counting (TCSPC) provides detailed information about the conformational changes of a biological…

Biological Physics · Physics 2009-11-13 N. Zarrabi , M. G. Dueser , S. Ernst , R. Reuter , G. D. Glick , S. D. Dunn , J. Wrachtrup , M. Boersch

We study quasi two-dimensional, monodisperse systems of active Brownian particles (ABPs) for a range of activities, stiffnesses, and densities. We develop a microscopic, analytical method for predicting the dense phase structure formed…

Soft Condensed Matter · Physics 2021-06-24 Nicholas Lauersdorf , Thomas Kolb , Moslem Moradi , Ehssan Nazockdast , Daphne Klotsa

Active Brownian particles (ABPs) represent a minimal model of active matter consisting of self-propelled spheres with purely repulsive interactions and rotational noise. Here, we examine the pressure of ABPs in two dimensions in both closed…

Soft Condensed Matter · Physics 2017-01-11 Adam Patch , David Yllanes , M. Cristina Marchetti

Recent studies reported that adenosine triphosphate (ATP) could inhibit as well as enhance the phase separation in prion-like proteins. The molecular mechanism underlying such a puzzling phenomenon remains elusive. Here, taking the fused in…

Soft Condensed Matter · Physics 2022-09-22 Chun-Lai Ren , Yue Shan , Pengfei Zhang , Hong-Ming Ding , Yu-qiang Ma

Atherosclerosis is a chronic inflammatory disease occurs due to plaque accumulation in the inner artery wall. In atherosclerotic plaque formation monocytes and macrophages play a significant role in controlling the disease dynamics. In the…

Dynamical Systems · Mathematics 2022-05-31 Debasmita Mukherjee , Sishu Shankar Muni , Hammed Olawale Fatoyinbo

A mathematical model of atherosclerosis of a blood vessel is advanced with regard for the entry of low-density lipoproteins (LDLs) into blood. For the first time, the influence of cytokines on the inflammation of a blood vessel at the…

Biological Physics · Physics 2025-03-25 V. I. Grytsay

We consider a one-dimensional run-and-tumble particle (RTP) confined by an external potential and coupled to a thermal reservoir. Starting from the corresponding Fokker-Planck equation, we derive an explicit expression for the local entropy…

Statistical Mechanics · Physics 2025-09-11 Oded Farago

Agglomeration, adsorption, and extraction in dispersed multiphase systems are ubiquitously encountered in biological systems, energy industry, and medical science. In this work, a novel lattice model is extended to the three-component…

Statistical Mechanics · Physics 2022-10-12 Yiran Li , Yunfan Huang , Xukang Lu , Moran Wang

A typical strategy of realizing an adiabatic change of a many-particle system is to vary parameters very slowly on a time scale $t_\text{r}$ much larger than intrinsic equilibration time scales. In the ideal case of adiabatic state…

Statistical Mechanics · Physics 2021-03-24 Philipp S. Weiß , Dennis Hardt , Achim Rosch