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Iso-flux tension propagation (IFTP) theory and Langevin dynamics (LD) simulations are employed to study the dynamics of channel-driven polymer translocation in which a polymer translocates into a narrow channel and the monomers in the…

Soft Condensed Matter · Physics 2022-05-16 Jalal Sarabadani , Ralf Metzler , Tapio Ala-Nissila

We investigated the translation of a protein through model nanopores using coarse-grained (CG) non-equilibrium molecular dynamics (NEMD) simulations and compared the mobilities with those obtained from previous coarse-grained equilibrium…

Computational Physics · Physics 2018-06-27 Navaneeth Haridasan , Sridhar Kumar Kannam , Santosh Mogurampelly , Sarith P Sathian

We investigate the translocation of a single stranded DNA through a pore which fluctuates between two conformations, using coupled master equations. The probability density function of the first passage times (FPT) of the translocation…

Statistical Mechanics · Physics 2007-05-23 O. Flomenbom , J. Klafter

Living organisms employ diverse strategies to navigate confined environments. Inspired by translocation observations on California blackworms (\textit{Lumbriculus variegatus}), we combine biological experiments and active-polymer…

Soft Condensed Matter · Physics 2025-10-21 K. R. Prathyusha , Paulami Sarkar , Justin Xu , Saad Bhamla

We investigate the dynamics of DNA translocation through a nanopore using 2D Langevin dynamics simulations, focusing on the dependence of the translocation dynamics on the details of DNA sequences. The DNA molecules studied in this work are…

Soft Condensed Matter · Physics 2008-02-05 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Aniket Bhattacharya

We propose a method for the theoretical investigation of polymer translocation through composite pore structures possessing arbitrarily specified geometries. Translocation through each constituent part of the composite is treated as being…

Soft Condensed Matter · Physics 2008-03-07 Aruna Mohan , Anatoly B. Kolomeisky , Matteo Pasquali

We analyze the translocation of a charged particle across an Alpha-Hemolysin (aHL) pore in the framework of a driven diffusion over an extended energy barrier generated by the electrical charges of the aHL. A one-dimensional electrostatic…

Biomolecules · Quantitative Biology 2015-10-15 Patrizio Ansalone , Mauro Chinappi , Lamberto Rondoni , Fabio Cecconi

We study the translocation of polymers across varying-section channels. Using systematic approximations, we derive a simplified model that reduces the problem of polymer translocation through varying-section channels to that of a point-like…

Soft Condensed Matter · Physics 2017-07-13 Valentino Bianco , Paolo Malgaretti

We study the conformation and dynamics of a single polymer chain that is pulled by a constant force applied at its one end with the other end free. Such a situation is relevant to the growing technology of manipulating individual…

Soft Condensed Matter · Physics 2015-06-04 Takahiro Sakaue , Takuya Saito , Hirofumi Wada

We investigate the influence of varying confinement on the dynamics of polymer translocation through a cone shaped channel. For this, a linear polymer chain is modeled by a self voiding walks (SAWs) on a square lattice. The cis-side of a…

Soft Condensed Matter · Physics 2024-01-10 Manish Dwivedi , Sumitra Rudra , Sanjay Kumar

Using Langevin dynamics simulations, we study a system of transversely propelling filament and passive Brownian particles. We consider a polymer whose monomers experience a constant propulsion force perpendicular to the local tangent in the…

Soft Condensed Matter · Physics 2022-12-29 K. R. Prathyusha

Monte Carlo simulations are used to study the translocation of a polymer into and out of a ellipsoidal cavity through a narrow pore. We measure the polymer free energy F as a function of a translocation coordinate, s, defined to be the…

Soft Condensed Matter · Physics 2015-05-20 James M. Polson

It is shown using the method of molecular dynamics that the motion of carbon nanoparticles (rectangular graphene flakes, spherical fullerenes of size $L<10$ nm) on the surface of a thermalized graphene sheet lying on a flat substrate can be…

Mesoscale and Nanoscale Physics · Physics 2022-11-30 Alexander V. Savin

We study a model of rolling particles subject to stochastic fluctuations, which may be relevant in systems of nano- or micro-scale particles where rolling is an approximation for strong static friction. We consider the simplest possible…

Mathematical Physics · Physics 2016-10-04 Miranda Holmes-Cerfon

We investigate the dynamics of pore-driven polymer translocation by theoretical analysis and molecular dynamics (MD) simulations. Using the tension propagation theory within the constant flux approximation we derive an explicit equation of…

Soft Condensed Matter · Physics 2015-06-23 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

We investigate the dynamics of nanoparticles in semidilute polymer solutions when the nanoparticles are comparably sized to the polymer coils using explicit- and implicit-solvent simulation methods. The nanoparticle dynamics are…

We analyse mobile-immobile transport of particles that switch between the mobile and immobile phases with finite rates. Despite this seemingly simple assumption of Poissonian switching we unveil a rich transport dynamics including…

Statistical Mechanics · Physics 2022-03-28 T. Doerries , A. V. Chechkin , R. Metzler

We present a Brownian dynamics model of driven polymer translocation, in which non-equilibrium memory effects arising from tension propagation (TP) along the cis side subchain are incorporated as a time-dependent friction. To solve the…

Soft Condensed Matter · Physics 2015-06-03 Timo Ikonen , Aniket Bhattacharya , Tapio Ala-Nissila , Wokyung Sung

We present a numerical study of forced polymer translocation by using two separate pore models. Both of them have been extensively used in previous forced translocation studies. We show that variations in the pore model affect the forced…

Biological Physics · Physics 2015-05-19 V. V. Lehtola , K. Kaski , R. P. Linna

Entropy-driven directed translocation of a flexible polymer through a cone-shaped channel is studied theoretically and using computer simulation. For a given length of the channel, the effective force of entropic origin acting on the…

Soft Condensed Matter · Physics 2015-06-12 Narges Nikoofard , Hamidreza Khalilian , Hossein Fazli