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In this paper, we study a nonlinear free boundary problem modeling the growth of spherically symmetric tumors. The tumor consists of a central necrotic core, an intermediate annual quiescent-cell layer, and an outer proliferating-cell…

Analysis of PDEs · Mathematics 2025-11-04 Junde Wu , Hao Xu , Yuehong Zhuang

Large-eddy simulations of a flat-plate boundary layer, without a leading edge, subject to multiple levels of incoming free stream turbulence are considered in the present work. Within an input-output model where non-linear terms of the…

Fluid Dynamics · Physics 2024-02-19 Diego C. P. Blanco , Ardeshir Hanifi , Dan S. Henningson , André V. G. Cavalieri

An intrinsic curvature model is investigated using the canonical Monte Carlo simulations on dynamically triangulated spherical surfaces of size upto N=4842 with two fixed-vertices separated by the distance 2L. We found a first-order…

Statistical Mechanics · Physics 2009-11-11 S. Obata , M. Egashira , T. Endo , H. Koibuchi

An additive growth curve model with orthogonal design matrices is proposed in which observations may have different profile forms. The proposed model allows us to fit data and then estimate parameters in a more parsimonious way than the…

Statistics Theory · Mathematics 2012-01-06 Jianhua Hu , Guohua Yan , Jinhong You

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

Analysis of PDEs · Mathematics 2013-06-11 Martin Kohlmann

We study the growth of degrees in many autonomous and non-autonomous lattice equations defined by quad rules with corner boundary values, some of which are known to be integrable by other characterisations. Subject to an enabling…

Exactly Solvable and Integrable Systems · Physics 2017-03-06 John A. G. Roberts , Dinh T. Tran

We derive optimal estimates for the Bergman kernel and the Bergman metric for certain model domains in $\mathbb{C}^2$ near boundary points that are of infinite type. Being unbounded models, these domains obey certain geometric constraints…

Complex Variables · Mathematics 2021-03-25 Gautam Bharali

We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…

Populations and Evolution · Quantitative Biology 2007-05-23 José F. Nieves , Marcelo R. Ubriaco

Based on numerical simulation and local stability analysis we describe the structure of the phase space of the edge/triangle model of random graphs. We support simulation evidence with mathematical proof of continuity and discontinuity for…

Combinatorics · Mathematics 2017-10-25 Richard Kenyon , Charles Radin , Kui Ren , Lorenzo Sadun

We study the asymptotic shape of the occupied region for monotone deterministic dynamics in d-dimensional Euclidean space parametrized by a threshold theta, and a Borel set N with positive and finite Lebesgue measure. If A_n denotes the…

patt-sol · Physics 2008-02-03 Janko Gravner , David Griffeath

In this work we study a tissue growth model with applications to tumour growth. The model is based on that of Perthame, Quir\'os, and V\'azquez proposed in 2014 but incorporates the advective effects caused, for instance, by the presence of…

Analysis of PDEs · Mathematics 2021-03-04 Noemi David , Markus Schmidtchen

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

The innumerable shapes of plant leaves present a challenge to the explanatory power of biophysical theory. A model is needed that can produce these shapes with a small set of parameters. This paper presents a simple model of leaf shape…

Tissues and Organs · Quantitative Biology 2010-04-27 David A. Young

Given recipe of qualitative, kinetic modelling by geometric methods of three-dimensional dendritic crystals. Characteristic features of the perturbations appearing on the surface of a spherical body, leading to different scenarios of the…

Materials Science · Physics 2018-10-05 Alexander S. Prokhoda

Two-dimensional $CP^{N-1}$ models are investigated by Monte Carlo methods on the lattice, for values of $N$ ranging from 2 to 21. Scaling and rotation invariance are studied by comparing different definitions of correlation length $\xi$.…

High Energy Physics - Lattice · Physics 2009-10-22 Massimo Campostrini , Paolo Rossi , Ettore Vicari

In this paper, we develop a sharp interface tumor growth model in two dimensions to study the effect of both the intratumoral structure using a controlled necrotic core and the extratumoral nutrient supply from vasculature on tumor…

Numerical Analysis · Mathematics 2022-03-30 Min-Jhe Lu , Wenrui Hao , Chun Liu , John Lowengrub , Shuwang Li

We briefly review the properties of radially growing interfaces and their connection to biological growth. We focus on simplified models which result from the abstraction of only considering domain growth and not the interface curvature.…

Statistical Mechanics · Physics 2011-10-04 Carlos Escudero

We present the results of an extension of our previous work on large-scale simulations of dynamically triangulated toroidal random surfaces embedded in $R^3$ with extrinsic curvature. We find that the extrinsic-curvature specific heat peak…

High Energy Physics - Theory · Physics 2009-10-22 Konstantinos Anagnostopoulos , Mark Bowick , Paul Coddington , Marco Falcioni , Leping Han , Geoffrey Harris , Enzo Marinari

We formulate and prove a shape theorem for a continuous-time continuous-space stochastic growth model under certain general conditions. Similarly to the classical lattice growth models the proof makes use of the subadditive ergodic theorem.…

Probability · Mathematics 2018-04-13 Viktor Bezborodov , Luca Di Persio , Tyll Krueger , Mykola Lebid , Tomasz Ożański

We consider the Helmholtz equation in an angular sector partially covered by a homogeneous layer of small thickness, denoted $\varepsilon$. We propose in this work an asymptotic expansion of the solution with respect to $\varepsilon$ at any…

Analysis of PDEs · Mathematics 2026-02-17 Cédric Baudet