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Digital monitoring studies collect real-time high frequency data via mobile sensors in the subjects' natural environment. This data can be used to model the impact of changes in physiology on recurrent event outcomes such as smoking, drug…

Methodology · Statistics 2022-04-15 Walter Dempsey

The development of enhanced sampling methods has greatly extended the scope of atomistic simulations, allowing long-time phenomena to be studied with accessible computational resources. Many such methods rely on the identification of an…

Computational Physics · Physics 2022-06-08 Luigi Bonati , GiovanniMaria Piccini , Michele Parrinello

Slice sampling is a well-established Markov chain Monte Carlo method for (approximate) sampling of target distributions which are only known up to a normalizing constant. The method is based on choosing a new state on a slice, i.e., a…

Computation · Statistics 2025-12-22 Kevin Bitterlich , Daniel Rudolf , Björn Sprungk

We propose a new approach for estimating the parameters of a probability distribution. It consists on combining two new methods of estimation. The first is based on the definition of a new distance measuring the difference between…

Methodology · Statistics 2008-12-30 Ahmed Guellil , Tewfik Kernane

Standard rare-event simulation techniques require exact distributional specifications, which limits their effectiveness in the presence of distributional uncertainty. To address this, we develop a novel framework for estimating rare-event…

Methodology · Statistics 2026-01-06 Dohyun Ahn , Huiyi Chen , Lewen Zheng

We formulate the statistics of the discrete multicomponent fragmentation event using a methodology borrowed from statistical mechanics. We generate the ensemble of all feasible distributions that can be formed when a single integer…

Statistical Mechanics · Physics 2020-07-03 Themis Matsoukas

Subsampling is a computationally efficient and scalable method to draw inference in large data settings based on a subset of the data rather than needing to consider the whole dataset. When employing subsampling techniques, a crucial…

Methodology · Statistics 2025-10-08 Amalan Mahendran , Helen Thompson , James M. McGree

We consider the problem of choosing design parameters to minimize the probability of an undesired rare event that is described through the average of $n$ iid random variables. Since the probability of interest for near optimal design…

Optimization and Control · Mathematics 2019-02-22 Amarjit Budhiraja , Shu Lu , Yang Yu , Quoc Tran-Dinh

We propose a new approach that combines multiple non-parametric likelihood-type components to build a data-driven approximation of the true likelihood function. Our approach is built on empirical likelihood, a non-parametric approximation…

Methodology · Statistics 2017-12-15 Adam Jaeger , Nicole Lazar

By far the most common way to estimate an expected loss in machine learning is to draw samples, compute the loss on each one, and take the empirical average. However, sampling is not necessarily optimal. Given an MLP at initialization, we…

Machine Learning · Computer Science 2026-05-18 Wilson Wu , Victor Lecomte , Michael Winer , George Robinson , Jacob Hilton , Paul Christiano

This article analyzes and compares two general techniques of rare event simulation for generating paths of Markov processes over fixed time horizons: exponential tilting and stochastic bridge. These two methods allow to accurately compute…

Statistical Mechanics · Physics 2025-08-27 Javier Aguilar , Riccardo Gatto

In this work, we propose an algorithm to simulate rare events for electronic circuit design. Our approach heavily relies on a smart use of importance sampling, which enables us to tackle probabilities of the magnitude 10 --10. Not only can…

Probability · Mathematics 2021-09-20 Xavier Jonsson , Jérôme Lelong

In Part I (arXiv:1911.00619) of this article, we proposed an importance sampling algorithm to compute rare-event probabilities in forward uncertainty quantification problems. The algorithm, which we termed the "Bayesian Inverse Monte Carlo…

Computation · Statistics 2019-11-06 Siddhant Wahal , George Biros

Rare events in molecular dynamics are often related to noise-induced transitions between different macroscopic states (e.g., in protein folding). A common feature of these rare transitions is that they happen on timescales that are on…

Probability · Mathematics 2026-01-06 Carsten Hartmann , Annika Jöster , Christof Schütte , Alexander Sikorski , Marcus Weber

The problem of sampling constrained continuous distributions has frequently appeared in many machine/statistical learning models. Many Monte Carlo Markov Chain (MCMC) sampling methods have been adapted to handle different types of…

Computation · Statistics 2023-02-21 Shiwei Lan , Lulu Kang

Although many computational methods for rare event sampling exist, this type of calculation is not usually practical for general nonequilibrium conditions, with macroscopically irreversible dynamics and away from both stationary and…

Mesoscale and Nanoscale Physics · Physics 2015-05-18 Joshua T. Berryman , Tanja Schilling

Estimating the expectations of functionals applied to sums of random variables (RVs) is a well-known problem encountered in many challenging applications. Generally, closed-form expressions of these quantities are out of reach. A naive…

Information Theory · Computer Science 2022-10-27 Eya Ben Amar , Nadhir Ben Rached , Abdul-Lateef Haji-Ali , Raúl Tempone

We introduce a new sample complexity measure, which we refer to as split-sample growth rate. For any hypothesis $H$ and for any sample $S$ of size $m$, the split-sample growth rate $\hat{\tau}_H(m)$ counts how many different hypotheses can…

Computer Science and Game Theory · Computer Science 2017-04-18 Vasilis Syrgkanis

Statistical procedures such as Bayes factor model selection and Bayesian model averaging require the computation of normalizing constants (e.g., marginal likelihoods). These normalizing constants are notoriously difficult to obtain, as they…

Computation · Statistics 2018-09-19 Quentin F. Gronau , Henrik Singmann , Eric-Jan Wagenmakers

We develop importance sampling based efficient simulation techniques for three commonly encountered rare event probabilities associated with random walks having i.i.d. regularly varying increments; namely, 1) the large deviation…

Probability · Mathematics 2014-09-30 Karthyek R. A. Murthy , Sandeep Juneja , Jose Blanchet