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We present the derivation of a new unidirectional model for We present the derivation of a new unidirectional model for unsteady mixed flows in non uniform closed water pipes. We introduce a local reference frame to take into account the…

Analysis of PDEs · Mathematics 2010-06-02 Christian Bourdarias , Mehmet Ersoy , Stéphane Gerbi

Computational cardiovascular flow modeling plays a crucial role in understanding blood flow dynamics. While 3D models provide acute details, they are computationally expensive, especially with fluid-structure interaction (FSI) simulations.…

Fluid Dynamics · Physics 2025-01-06 Hunor Csala , Arvind Mohan , Daniel Livescu , Amirhossein Arzani

We present a unified mathematical framework for modeling blood and lymph flow in biological vessels, with a particular focus on lymph transport through lymphangions. Starting from first principles, we rigorously derive a system of partial…

Analysis of PDEs · Mathematics 2026-03-03 Bogna Jaszczak-Dyka , Łukasz Płociniczak

We are interested in a reduced order method for the efficient simulation of blood flow in arteries. The blood dynamics is modeled by means of the incompressible Navier-Stokes equations. Our algorithm is based on an approximated…

Numerical Analysis · Mathematics 2021-04-07 Luca Pegolotti , Martin Pfaller , Alison Marsden , Simone Deparis

Reduced-order models based on physics are a popular choice in cardiovascular modeling due to their efficiency, but they may experience reduced accuracy when working with anatomies that contain numerous junctions or pathological conditions.…

Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…

Fluid Dynamics · Physics 2021-06-15 Giulia Bertaglia , Valerio Caleffi , Alessandro Valiani

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

We develop two mathematical lumped parameter models for blood pressure distribution in the Fontan blood flow circulation: an ODE based spatially homogeneous model and a PDE based spatially inhomogeneous model. We present numerical…

Analysis of PDEs · Mathematics 2018-06-08 J. P. Keener , M. Chugunova , R. M. Taranets , M. G. Doyle

Physics-based models often involve large systems of parametrized partial differential equations, where design parameters control various properties. However, high-fidelity simulations of such systems on large domains or with high grid…

Computational Physics · Physics 2025-05-15 Diba Behnoudfar

Extracting information on fluid motion directly from images is challenging. Fluid flow represents a complex dynamic system governed by the Navier-Stokes equations. General optical flow methods are typically designed for rigid body motion,…

Machine Learning · Computer Science 2022-06-23 Mingrui Zhang , Jianhong Wang , James Tlhomole , Matthew D. Piggott

We present a reduced order model for three dimensional unsteady pressure-driven flows in micro-channels of variable cross-section. This fast and accurate model is valid for long channels, but allows for large variations in the channel's…

Fluid Dynamics · Physics 2021-08-09 Leila Issa , Sajed Medlej , Ali Saleh , Issam Lakkis

This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…

The discretization of reduced one-dimensional hyperbolic models of blood flow using the Lax-Friedrichs method is discussed. Employing the well-established central scheme in this domain significantly simplifies the implementation of specific…

Numerical Analysis · Mathematics 2025-07-22 Anika Beckers , Niklas Kolbe

In this article we present a novel staggered semi-implicit hybrid finite-volume/finite-element (FV/FE) method for the resolution of weakly compressible flows in two and three space dimensions. The pressure-based methodology introduced in…

Numerical Analysis · Mathematics 2020-06-16 A. Bermúdez , S. Busto , M. Dumbser , J. L. Ferrín , L. Saavedra , M. E. Vázquez-Cendón

We propose PROSE-FD, a zero-shot multimodal PDE foundational model for simultaneous prediction of heterogeneous two-dimensional physical systems related to distinct fluid dynamics settings. These systems include shallow water equations and…

Machine Learning · Computer Science 2024-09-17 Yuxuan Liu , Jingmin Sun , Xinjie He , Griffin Pinney , Zecheng Zhang , Hayden Schaeffer

Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have…

The present work proposes a well-balanced finite volume-type numerical method for the solution of non-conservative hyperbolic partial differential equations (PDEs) with source terms. The method is characterized, first, by the use of a…

Numerical Analysis · Mathematics 2026-05-06 Chiara Colombo , Caterina Dalmaso , Lucas O. Müller , Annunziato Siviglia

Predictive high-fidelity finite element simulations of human cardiac mechanics co\-mmon\-ly require a large number of structural degrees of freedom. Additionally, these models are often coupled with lumped-parameter models of hemodynamics.…

Computational Engineering, Finance, and Science · Computer Science 2020-02-18 Martin R. Pfaller , Maria Cruz Varona , Johannes Lang , Cristóbal Bertoglio , Wolfgang A. Wall

We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…

Medical Physics · Physics 2019-07-29 Olivier Adjoua , Stéphanie Pitre-Champagnat , Didier Lucor

It is well known, thanks to Lax-Wendroff theorem, that the local conservation of a numerical scheme for a conservative hyperbolic system is a simple and systematic way to guarantee that, if stable, a scheme will provide a sequence of…

Numerical Analysis · Mathematics 2023-01-16 Remi Abgrall , P Bacigaluppi , S Tokareva
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