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We study a dynamical curvature instability caused by a local chemical modification of a phospholipid membrane. In our experiments, a basic solution is microinjected close to a giant unilamellar vesicle, which induces a local chemical…

Soft Condensed Matter · Physics 2015-03-19 Anne-Florence Bitbol , Jean-Baptiste Fournier , Miglena I. Angelova , Nicolas Puff

We study the deformation of a lipid membrane in response to a local pH modification. Experimentally, a basic solution is microinjected close to a giant unilamellar vesicle. A local deformation appears in the zone of the membrane that is…

We present Monte Carlo simulations of an ultra coarse-grained lipid bilayer with different number of lipids on both leaflets. In the simulations, we employ a new method for measuring the elastic parameters of the membrane, including the…

Soft Condensed Matter · Physics 2025-05-20 Oded Farago

We discuss the spatiotemporal behavior of local density and its relation to dynamical heterogeneity in a highly supercooled liquid by using molecular dynamics simulations of a binary mixture with different particle sizes in two dimensions.…

Soft Condensed Matter · Physics 2015-03-20 Hayato Shiba , Takeshi Kawasaki

The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or…

Soft Condensed Matter · Physics 2009-11-10 Pierre Sens

We theoretically investigate the relaxation dynamics of a nearly-flat binary lipid bilayer membrane by taking into account the membrane tension, hydrodynamics of the surrounding fluid, inter-monolayer friction and mutual diffusion in each…

Soft Condensed Matter · Physics 2016-05-05 Ryuichi Okamoto , Yuichi Kanemori , Shigeyuki Komura , Jean-Baptiste Fournier

Using molecular dynamics, this study investigates the local elastic properties of transverse shear deformation of lipid membranes. The analysis demonstrates that transverse shear deformation induces anisotropy in the local stress profile of…

Soft Condensed Matter · Physics 2025-11-12 Konstantin V. Pinigin

We present a first-principles formalism for studying dynamical heterogeneities in glass forming liquids. Based on the Non-Equilibrium Self-Consistent Generalized Langevin Equation theory, we were able to describe the time-dependent local…

Soft Condensed Matter · Physics 2022-04-06 J. Lira-Escobedo , J. R. Velez-Cordero , Pedro E. Ramírez-González

Adsorption of proteins onto membranes can alter the local membrane curvature. This phenomenon has been observed in biological processes such as endocytosis, tubulation and vesiculation. However, it is not clear how the local surface…

Cell Behavior · Quantitative Biology 2016-04-28 Padmini Rangamani , Kranthi Kiran Mandadapu , George Oster

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

Quantitative Methods · Quantitative Biology 2025-01-24 Anil Cengiz , Sean D Lawley

Nonequilibrium membrane pattern formation is studied using meshless membrane simulation. We consider that molecules bind to either surface of a bilayer membrane and move to the opposite leaflet by flip--flop. When binding does not modify…

Soft Condensed Matter · Physics 2025-01-14 Hiroshi Noguchi

Diffusion-mediated surface phenomena are crucial for human life and industry, with examples ranging from oxygen capture by lung alveolar surface to heterogeneous catalysis, gene regulation, membrane permeation and filtration processes.…

Statistical Mechanics · Physics 2020-08-19 Denis S. Grebenkov

The near membrane layer is defined as a region where the concentration of the substance transported across the membrane drops $k$ times. The time evolution of such a layer is studied experimentally by means of the laser interferometric…

Condensed Matter · Physics 2007-05-23 Kazimierz Dworecki , Tadeusz Kosztolowicz , Slawomir Wasik , Stanislaw Mrowczynski

The slow flow of amorphous solids exhibits striking heterogeneities: swift localised particle rearrangements take place in the midst of a more or less homogeneously deforming medium. Recently, experimental as well as numerical work has…

Soft Condensed Matter · Physics 2014-03-04 Alexandre Nicolas , Joerg Rottler , Jean-Louis Barrat

In development and homeostasis, multi-cellular systems exhibit spatial and temporal heterogeneity in their biochemical and mechanical properties. Nevertheless, it remains unclear how spatiotemporally heterogeneous forces affect the…

Soft Condensed Matter · Physics 2022-02-18 Takaki Yamamoto , Daniel M. Sussman , Tatsuo Shibata , M. Lisa Manning

Lipid structures exhibit complex and highly dynamic lateral structure; and changes in lipid density and fluidity are believed to play an essential role in membrane targeting and function. The dynamic structure of liquids on the molecular…

Soft Condensed Matter · Physics 2016-12-21 Neda Dadashvand , Christina M. Othon

We derive the expression of the stress tensor for one and two-component lipid membranes with density and composition inhomogeneities. We first express the membrane stress tensor as a function of the free-energy density by means of the…

Soft Condensed Matter · Physics 2015-03-17 Anne-Florence Bitbol , Luca Peliti , Jean-Baptiste Fournier

Bilayer lipid membranes (BLMs) are an essential component of many biological systems, forming a functional barrier between the cell and the surrounding environment. When the membrane relaxes from a structural perturbation, the dynamics of…

Soft Condensed Matter · Physics 2015-07-27 R. J. Bingham , S. W. Smye , P. D. Olmsted

We theoretically investigate the thermally-driven curvature and lipid density fluctuations of a quasi-spherical vesicle, accounting for the dissipation due to monolayer viscosity and intermonolayer friction. The theory predicts that…

Soft Condensed Matter · Physics 2026-05-06 Petia M. Vlahovska , Rony Granek

A theory and computational method are provided for the calculation of lipid membranes elastic parameters, which overcomes the difficulties of the existing approaches and can be applied not only to single-component but also to…

Soft Condensed Matter · Physics 2023-07-06 Maksim A. Kalutsky , Timur R. Galimzyanov , Konstantin V. Pinigin
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