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Control of molecular rotations by laser fields is an active area of research focusing on the alignment/orientation of otherwise isotropic molecular samples. Oriented molecules are useful in many applications, such as molecular orbital…

Chemical Physics · Physics 2020-07-03 Long Xu , Ilia Tutunnikov , Erez Gershnabel , Yehiam Prior , Ilya Sh. Averbukh

X-ray dark-field imaging visualises scattering from sample microstructure, and has found application in medical and security contexts. While most X-ray dark-field imaging techniques rely on masks, gratings, or crystals, recent work on the…

The advent of single molecule microscopy has revolutionized biological investigations by providing a powerful tool for the study of intercellular and intracellular trafficking processes of protein molecules which was not available before…

Signal Processing · Electrical Eng. & Systems 2020-11-26 Milad R. Vahid , Bernard Hanzon , Raimund J. Ober

Imaging of the structure of single proteins or other biomolecules with atomic resolution would be enormously beneficial to structural biology. X-ray free-electron lasers generate highly intense and ultrashort x-ray pulses, providing a route…

Atomic Physics · Physics 2014-07-30 Jan Malte Slowik , Sang-Kil Son , Gopal Dixit , Zoltan Jurek , Robin Santra

Radiation damage is considered to be the major problem that still prevents imaging an individual biological molecule for structural analysis. So far, all known mapping techniques using sufficient short wave-length radiation, be it X-rays or…

Biological Physics · Physics 2010-10-28 Matthias Germann , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

The manipulation of the motion of neutral molecules with electric or magnetic fields has seen tremendous progress over the last decade. Recently, these techniques have been extended to the manipulation of large and complex molecules. In…

Chemical Physics · Physics 2011-04-07 Frank Filsinger , Gerard Meijer , Henrik Stapelfeldt , Henry N. Chapman , Jochen Küpper

We demonstrate theoretically and experimentally that the three-dimensional orientation of a single fluorescent nano-emitter can be determined by polarization analysis of the emitted light (while excitation polarization analysis provides…

The advent of the X-ray Free Electron Laser (XFEL) has made it possible to record diffraction snapshots of biological entities injected into the X-ray beam before the onset of radiation damage. Algorithmic means must then be used to…

Biological Physics · Physics 2014-04-30 A. Hosseinizadeh , P. Schwander , A. Dashti , R. Fung , R. M. D'Souza , A. Ourmazd

We present a systematic study of the unbinned, photon-by-photon likelihood technique which can be used as an alternative method to analyse phase-dependent, X-ray spectro-polarimetric observations obtained with IXPE and other photo-electric…

Instrumentation and Methods for Astrophysics · Physics 2023-01-25 Denis González-Caniulef , Ilaria Caiazzo , Jeremy Heyl

We study single-photon ionization of aligned H$_2^+$ in a high-frequency low-intensity laser field. We focus on the case where the laser frequency is not far larger than the ionization potential of the target. The calculated photoelectron…

Atomic Physics · Physics 2022-12-02 F. B. Zhang , J. Y. Che , W. Y. Li , C. Chen , Y. J. Chen

X-ray free-electron lasers (XFELs) have been widely used for applications such as X-ray crystallography and magnetic spin probes because of their unprecedented performance. Recently, time-resolved X-ray magnetic circular dichroism (XMCD)…

Instrumentation and Detectors · Physics 2018-07-04 Bangjie Deng , Jiawei Yan , Qingmin Zhang , Yaodong Sang , Haixiao Deng

A method is proposed for obtaining three simultaneous projections of a target from a single radiation pulse, which also allows the relative orientation of successive targets to be determined. The method has application to femtosecond X-ray…

Soft Condensed Matter · Physics 2009-05-27 K. E. Schmidt , J. C. H. Spence , U. Weierstall , R. Kirian , X. Wang , D. Starodub , H. N. Chapman , M. R. Howells , R. B. Doak

We consider the theory of the non-linear spectroscopy for a single molecule undergoing stochastic dynamics and interacting with a sequence of two laser pulses. General expressions for photon counting statistics are obtained, and an exact…

Optics · Physics 2008-01-13 F. Shikerman , E. Barkai

Here we propose to exploit the low energy bandwidth, small wavelength and penetration power of ultrashort pulses from XFELs for resonant Small Angle Scattering (SAXS) on plasma structures in laser excited plasmas. Small angle scattering…

Plasma Physics · Physics 2016-03-09 Thomas Kluge , M. Bussmann , H. -K. Chung , C. Gutt , L. G. Huang , M. Zacharias , U. Schramm , T. E. Cowan

Our ability to optically interrogate nanoscopic objects is controlled by the difference between their extinction cross sections and the diffraction limited area to which light can be confined in the far field. We show that a partially…

Optics · Physics 2016-11-17 Daniel Cole , Gavin Young , Alexander Weigel , P. Kukura

Dark field X-ray microscopy (DXFM) can visualize microstructural distortions in bulk crystals. Using the femtosecond X-ray pulses generated by X-ray free-electron lasers (XFEL), DFXM can achieve sub-{\mu}m spatial resolution and <100 fs…

We consider deflection of polarizable molecules by inhomogeneous optical fields, and analyze the role of molecular orientation and rotation in the scattering process. It is shown that molecular rotation induces spectacular rainbow-like…

Quantum Physics · Physics 2015-05-19 E. Gershnabel , I. Sh. Averbukh

We study tunneling ionization of HeH+ in strong elliptical laser fields numerically and analytically. The calculated photoelectron momentum distribution (PMD) show two different offset angles corresponding to ionization events occurring in…

Atomic Physics · Physics 2025-11-18 Jiayin Che , Sheng Ye , Shiqi Shen , Weiyan Li , Yanjun Chen

We present an analytical approach to the calculation of the linewidth and lineshift of an atom or molecule in the near field of a structured dielectric surface. For soft surface corrugations with amplitude lambda/50, we find variations of…

Optics · Physics 2009-10-31 Carsten Henkel , Vahid Sandoghdar

X-ray free electron laser (XFEL) can provide X-ray light with about four order of magnitude higher flux than synchrotron radiation. Pulse light from XFEL interacts with the target and the resulting photons are collected by detectors. The…

Instrumentation and Detectors · Physics 2021-10-13 Shuo Zhang , Jing-Kai Xia , Xu-Dong Ju