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We derive a physiologically structured multiscale model for biofilm development. The model has components on two spatial scales, which induce different time scales into the problem. The macroscopic behavior of the system is modeled using…

Cell Behavior · Quantitative Biology 2023-02-14 Bruce P. Ayati , Isaac Klapper

Scaling long-context ability is essential for Large Language Models (LLMs). To amortize the memory consumption across multiple devices in long-context training, inter-data partitioning (a.k.a. Data Parallelism) and intra-data partitioning…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-01 Hao Ge , Junda Feng , Qi Huang , Fangcheng Fu , Xiaonan Nie , Lei Zuo , Haibin Lin , Bin Cui , Xin Liu

Autonomous language-guided navigation in large-scale outdoor environments remains a key challenge in mobile robotics, due to difficulties in semantic reasoning, dynamic conditions, and long-term stability. We propose CausalNav, the first…

Robotics · Computer Science 2026-01-06 Hongbo Duan , Shangyi Luo , Zhiyuan Deng , Yanbo Chen , Yuanhao Chiang , Yi Liu , Fangming Liu , Xueqian Wang

We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problems in biology with additional, far-reaching implications…

Pathology and anatomy are two essential groups of semantics in medical data. Pathology describes what the diseases are, while anatomy explains where the diseases occur. They describe diseases from different perspectives, providing…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Wenrui Fan , Mohammod N. I. Suvon , Shuo Zhou , Xianyuan Liu , Samer Alabed , Venet Osmani , Andrew J. Swift , Chen Chen , Haiping Lu

We introduce a natural language interface for building stochastic pi calculus models of biological systems. In this language, complex constructs describing biochemical events are built from basic primitives of association, dissociation and…

Programming Languages · Computer Science 2009-11-13 Ozan Kahramanoğullari , Luca Cardelli , Emmanuelle Caron

In today's world of big data, computational analysis has become a key driver of biomedical research. Recent exponential growth in the volume of available omics data has reshaped the landscape of contemporary biology, creating demand for a…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-09 Jaqueline J. Brito , Thiago Mosqueiro , Jeremy Rotman , Victor Xue , Douglas J. Chapski , Juan De la Hoz , Paulo Matias , Lana Martin , Alex Zelikovsky , Matteo Pellegrinni , Serghei Mangul

Visual neuroprostheses (bionic eye) aim to restore a rudimentary form of vision by translating camera input into patterns of electrical stimulation. To improve scene understanding under extreme resolution and bandwidth constraints, prior…

Human-Computer Interaction · Computer Science 2025-07-16 Justin M. Kasowski , Apurv Varshney , Michael Beyeler

Biological cells are the prototypical example of active matter. Cells sense and respond to mechanical, chemical and electrical environmental stimuli with a range of behaviors, including dynamic changes in morphology and mechanical…

Computational Engineering, Finance, and Science · Computer Science 2017-02-28 Endre Somogyi , James A. Glazier

We present a bigraphical framework suited for modeling biological systems both at protein level and at membrane level. We characterize formally bigraphs corresponding to biologically meaningful systems, and bigraphic rewriting rules…

Computational Engineering, Finance, and Science · Computer Science 2009-11-25 Giorgio Bacci , Davide Grohmann , Marino Miculan

The applicability of computational models to the biological world is an active topic of debate. We argue that a useful path forward results from abandoning hard boundaries between categories and adopting an observer-dependent, pragmatic…

Multiagent Systems · Computer Science 2022-12-22 Joshua Bongard , Michael Levin

Signalling pathways are abstractions that help life scientists structure the coordination of cellular activity. Cross-talk between pathways accounts for many of the complex behaviours exhibited by signalling pathways and is often critical…

Computational Engineering, Finance, and Science · Computer Science 2010-02-23 Robin Donaldson , Muffy Calder

We present a semantic feedback framework that enables natural language to guide the evolution of artificial life systems. Integrating a prompt-to-parameter encoder, a CMA-ES optimizer, and CLIP-based evaluation, the system allows user…

Artificial Intelligence · Computer Science 2025-07-08 Shuowen Li , Kexin Wang , Minglu Fang , Danqi Huang , Ali Asadipour , Haipeng Mi , Yitong Sun

The genetic blueprint for the essential functions of life is encoded in DNA, which is translated into proteins -- the engines driving most of our metabolic processes. Recent advancements in genome sequencing have unveiled a vast diversity…

Neural and Evolutionary Computing · Computer Science 2024-06-12 James S. L. Browning , Daniel R. Tauritz , John Beckmann

We propose a Bayesian model of unsupervised semantic role induction in multiple languages, and use it to explore the usefulness of parallel corpora for this task. Our joint Bayesian model consists of individual models for each language plus…

Computation and Language · Computer Science 2016-03-07 Nikhil Garg , James Henderson

A novel language system has given rise to promising alternatives to standard formal and processor network models of computation. An interstring linked with a abstract machine environment, shares sub-expressions, transfers data, and…

Programming Languages · Computer Science 2010-05-31 Alexander Victor Berka

The massively parallel nature of biological information processing plays an important role for its superiority to human-engineered computing devices. In particular, it may hold the key to overcoming the von Neumann bottleneck that limits…

Given a pool of observations selected from a sensor stream, input data can be robustly represented, via a multiscale process, in terms of invariant concepts, and themes. Applying this to episodic natural language data, one may obtain a…

Artificial Intelligence · Computer Science 2020-10-19 Mark Burgess

We define BioScapeL, a stochastic pi-calculus in 3D-space. A novel aspect of BioScapeL is that entities have programmable locations. The programmer can specify a particular location where to place an entity, or a location relative to the…

Programming Languages · Computer Science 2014-04-02 Adriana Compagnoni , Paola Giannini , Catherine Kim , Matthew Milideo , Vishakha Sharma

Translational medicine turns underspecified development goals into evidence synthesis that must combine literature, trials, patents, and quantitative multi-omics analysis while preserving identifiers, uncertainty, and retrievable…