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Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

Neurons and Cognition · Quantitative Biology 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

A developmental disorder that severely damages communicative and social functions, the Autism Spectrum Disorder (ASD) also presents aspects related to mental rigidity, repetitive behavior, and difficulty in abstract reasoning. More,…

Neural and Evolutionary Computing · Computer Science 2018-11-20 Daniele Q. M. Madureira , Vera Lucia P. S. Caminha , Rogerio Salvini

Autism spectrum disorder (ASD) is regarded as a brain disease with globally disrupted neuronal networks. Even though fMRI studies have revealed abnormal functional connectivity in ASD, they have not reached a consensus of the disrupted…

Computer Vision and Pattern Recognition · Computer Science 2017-07-26 Hongyoon Choi

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

While the prevalence of Autism Spectrum Disorder (ASD) is increasing, research continues in an effort to identify common etiological and pathophysiological bases. In this regard, modern machine learning and network science pave the way for…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Sarah Itani , Dorina Thanou

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

Applications · Statistics 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju

Background: Previous functional connectivity studies have found both hypo- and hyper-connectivity in brains of individuals having autism spectrum disorder (ASD). Here we studied abnormalities in functional brain subnetworks in…

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

Neurons and Cognition · Quantitative Biology 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

To uncover the underlying mechanisms of mental disorders such as attention deficit hyperactivity disorder (ADHD) for improving both early diagnosis and therapy, it is increasingly recognized that we need a better understanding of how the…

Biological Physics · Physics 2011-12-16 Xiaoxi Ji , Wei Cheng , Jie Zhang , Tian Ge , Li Sun , Yufeng Wang , Jianfeng Feng

Autism Spectrum Disorder (ASD) is a complex neurological condition characterized by varied developmental impairments, especially in communication and social interaction. Accurate and early diagnosis of ASD is crucial for effective…

Machine Learning · Computer Science 2025-03-18 Suchanuch Piriyasatit , Chaohao Yuan , Ercan Engin Kuruoglu

What makes a network complex, in addition to its size, is the interconnected interactions between elements, disruption of which inevitably results in dysfunction. Likewise, the brain networks' complexity arises from interactions beyond pair…

Neurons and Cognition · Quantitative Biology 2022-04-19 Z. Moradimanesh , R. Khosrowabadi , M. Eshaghi Gordji , G. R. Jafari

Autism Spectrum Disorder (ASD) is a prevalent neurological disorder. However, the multi-faceted symptoms and large individual differences among ASD patients are hindering the diagnosis process, which largely relies on subject descriptions…

Neurons and Cognition · Quantitative Biology 2024-11-11 Yuzhe Chen , Dayu Qin , Ercan Engin Kuruoglu

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

Objective. The paper investigates the presence of autism using the functional brain connectivity measures derived from electro-encephalogram (EEG) of children during face perception tasks. Approach. Phase synchronized patterns from…

Currently, the diagnosis of Autism Spectrum Disorder (ASD) is dependent upon a subjective, time-consuming evaluation of behavioral tests by an expert clinician. Non-invasive functional MRI (fMRI) characterizes brain connectivity and may be…

Machine Learning · Computer Science 2020-05-26 Cooper J. Mellema , Alex Treacher , Kevin P. Nguyen , Albert Montillo

Background: Non-linear alterations in brain network connectivity may represent early neural signatures of Alzheimer's disease (AD) pathology in cognitively normal older adults. Understanding these changes and their cognitive relevance may…

Neurons and Cognition · Quantitative Biology 2026-04-22 Junjie Wu , Benjamin B Risk , Taylor A James , Nicholas Seyfried , David W Loring , Felicia C Goldstein , Allan I Levey , James J Lah , Deqiang Qiu

Autism spectrum disorder (ASD) affects the brain connectivity at different levels. Nonetheless, non-invasively distinguishing such effects using magnetic resonance imaging (MRI) remains very challenging to machine learning diagnostic…

Machine Learning · Computer Science 2020-04-29 Ismail Bilgen , Goktug Guvercin , Islem Rekik

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

Neurons and Cognition · Quantitative Biology 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu

While differences in patterns of functional connectivity and neural synchronization have been reported between individuals on the autism spectrum and neurotypical peers at various age stages, these differences appear to be subtle and may…

Neurons and Cognition · Quantitative Biology 2025-07-15 Sungwoo Ahn , Leonid L Rubchinsky , Evie A Malaia

Autism Spectrum Disorder (ASD) is characterized by an altered phenotype in social interaction and communication. Additionally, autism typically manifests differently in females as opposed to males: a phenomenon that has likely led to…

Neurons and Cognition · Quantitative Biology 2024-05-08 Michelle McCleod , Sean Borneman , Evie Malaia
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